Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(142 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(138 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(14 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(56 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5903 produtos de "Apoptose"
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Ethoxysanguinarine
CAS:Ethoxysanguinarine inhibits HuAChE and HuBuChE with IC50s of 0.83 and 4.20 μM, respectively.Fórmula:C22H19NO5Pureza:99.24% - 99.48%Cor e Forma:SolidPeso molecular:377.39Avadomide
CAS:<p>Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.</p>Fórmula:C14H14N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:286.29Sincalide
CAS:Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.Fórmula:C49H62N10O16S3Pureza:98.32%Cor e Forma:SolidPeso molecular:1143.27Hematoporphyrin dihydrochloride
CAS:<p>Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins.</p>Fórmula:C34H40Cl2N4O6Pureza:90.11%Cor e Forma:SolidPeso molecular:671.61PluriSIn 1
CAS:PluriSIn 1 (NSC 14613) blocks SCD1, key in oleic acid creation, showing lipid metabolism's role in hPSCs.Fórmula:C12H11N3OPureza:99.19% - 99.63%Cor e Forma:SolidPeso molecular:213.24BTSA1
CAS:BTSA1: High-affinity BAX activator inducing conformational changes for apoptosis.Fórmula:C21H14N6OS2Pureza:99.60% - 99.71%Cor e Forma:SolidPeso molecular:430.51Cambinol
CAS:Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.Fórmula:C21H16N2O2SPureza:98.02% - 99.83%Cor e Forma:SolidPeso molecular:360.43SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Fórmula:C24H28Cl2N2O4Pureza:99.00% - ≥95%Cor e Forma:SolidPeso molecular:479.4GSK2801
CAS:<p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>Fórmula:C20H21NO4SPureza:97.78% - 99.45%Cor e Forma:SolidPeso molecular:371.45Naphthazarin
CAS:<p>Naphthazarin triggers apoptosis, has anti-tumor effects via oxidative stress, mitochondrial AIF, microtubule depolymerization, and p53/p21 activation.</p>Fórmula:C10H6O4Pureza:98.12% - 99.87%Cor e Forma:Dark Purple To Brown-Black PowderPeso molecular:190.15DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Cor e Forma:White SolidPeso molecular:432.46Sophoraflavanone G
CAS:<p>Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related</p>Fórmula:C25H28O6Pureza:97.09% - 99.77%Cor e Forma:SolidPeso molecular:424.49BMS-833923
CAS:<p>BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).</p>Fórmula:C30H27N5OPureza:99.47% - 99.76%Cor e Forma:SolidPeso molecular:473.57Eriocalyxin B
CAS:Eriocalyxin B triggers apoptosis in pancreatic cancer via caspase, p53, and STAT3 inhibition.Fórmula:C20H24O5Pureza:99.84%Cor e Forma:SolidPeso molecular:344.4Aristolactam I
CAS:<p>Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.</p>Fórmula:C17H11NO4Pureza:98.98% - 99.63%Cor e Forma:SolidPeso molecular:293.27Nimustine Hydrochloride
CAS:<p>Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.</p>Fórmula:C9H14Cl2N6O2Pureza:98.80%Cor e Forma:SolidPeso molecular:309.15Nirogacestat
CAS:Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).Fórmula:C27H41F2N5OPureza:97.98% - 99.63%Cor e Forma:SolidPeso molecular:489.64Madecassoside
CAS:Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFórmula:C48H78O20Pureza:99.46% - 99.85%Cor e Forma:White PowderPeso molecular:975.12NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Fórmula:C27H34N4O5Pureza:99.59%Cor e Forma:SolidPeso molecular:494.58Quinacrine acetate
CAS:Quinacrine acetate is a histamine N-methyltransferase inhibitor.Fórmula:C25H34ClN3O3Cor e Forma:SolidPeso molecular:460.01Prexasertib
CAS:Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Fórmula:C18H19N7O2Pureza:97.3% - 98.23%Cor e Forma:SolidPeso molecular:365.39Metformin glycinate
CAS:Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Fórmula:C6H16N6O2Cor e Forma:SolidPeso molecular:204.23AKN-028 trifluoroacetate
CAS:AKN-028 trifluoroacetate causes cell cycle arrest and lowers Myc genes and tyrosine kinase activity in AML.Fórmula:C19H15F3N6O2Cor e Forma:SolidPeso molecular:416.36Tivantinib
CAS:Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.Fórmula:C23H19N3O2Pureza:98% - 99.41%Cor e Forma:SolidPeso molecular:369.42Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Fórmula:C47H55ClF3N5O6S3Pureza:95.82% - >99.99%Cor e Forma:Pale Yellow SolidPeso molecular:974.61Propylparaben
CAS:Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agentFórmula:C10H12O3Pureza:99.84%Cor e Forma:White Solid CrystallinePeso molecular:180.20Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Fórmula:C19H21ClN4OPureza:99.26%Cor e Forma:SolidPeso molecular:356.85AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Fórmula:C21H21N3O2SPureza:97.24% - 99.83%Cor e Forma:SolidPeso molecular:379.48CCCP
CAS:CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.Fórmula:C9H5ClN4Pureza:97.15% - 99.64%Cor e Forma:Yellow To Orange PowderPeso molecular:204.62Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Cor e Forma:SolidPeso molecular:320.26Tubeimoside I
CAS:<p>Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).</p>Fórmula:C63H98O29Pureza:98.89% - 99.94%Cor e Forma:SolidPeso molecular:1319.4320(R)-Ginsenoside Rh2
CAS:20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.Fórmula:C36H62O8Pureza:99.58%Cor e Forma:SolidPeso molecular:622.87NSC59984
CAS:<p>NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.</p>Fórmula:C12H15N3O4Pureza:99.33% - 99.59%Cor e Forma:SolidPeso molecular:265.27PRLX-93936
CAS:PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.Fórmula:C21H24N4O2Cor e Forma:SolidPeso molecular:364.44Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Cor e Forma:Orange To Red SolidPeso molecular:442.47Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.91LY-411575
CAS:<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Fórmula:C26H23F2N3O4Pureza:97.03% - 99.38%Cor e Forma:SolidPeso molecular:479.485'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Fórmula:C11H15N5O3SPureza:99.32% - 99.34%Cor e Forma:SolidPeso molecular:297.33LDN-57444
CAS:LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .Fórmula:C17H11Cl3N2O3Pureza:97.8% - 99.87%Cor e Forma:SolidPeso molecular:397.64Capmatinib 2HCl.H2O
CAS:Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Fórmula:C23H21Cl2FN6O2Pureza:99.77%Cor e Forma:SolidPeso molecular:503.36Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Cor e Forma:White To Off-White SolidPeso molecular:554.72PS-1145
CAS:<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Fórmula:C17H11ClN4OPureza:98.81% - >99.99%Cor e Forma:SolidPeso molecular:322.75INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Fórmula:C20H21N3O5SPureza:99.5%Cor e Forma:SolidPeso molecular:415.46GW779439X
CAS:GW779439X is an inhibitor of CDK.Fórmula:C22H21F3N8Pureza:97.87%Cor e Forma:SolidPeso molecular:454.45VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Fórmula:C19H17ClN2O5Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:388.8MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Fórmula:C22H28O3Pureza:98.69% - 99.86%Cor e Forma:SolidPeso molecular:340.46FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Fórmula:C25H31N3O5S2Pureza:99.72% - 99.78%Cor e Forma:SolidPeso molecular:517.66Volasertib
CAS:<p>Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.</p>Fórmula:C34H50N8O3Pureza:98% - 99.72%Cor e Forma:SolidPeso molecular:618.81
