Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(6 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(106 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(59 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6041 produtos de "Apoptose"
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DX2-201
CAS:DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.Fórmula:C18H28N2O6S2Cor e Forma:SolidPeso molecular:432.55Sanazole
CAS:Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.Fórmula:C7H11N5O4Cor e Forma:SolidPeso molecular:229.19RET-IN-8
CAS:RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.Fórmula:C27H30N6O3Cor e Forma:SolidPeso molecular:486.57AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45MDM2-p53-IN-16
CAS:MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Fórmula:C32H33N3O5Cor e Forma:SolidPeso molecular:539.62EGFR-IN-59
CAS:EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57PARP1-IN-31
CAS:PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).Fórmula:C22H15ClFN3O2Pureza:98.99%Cor e Forma:SolidPeso molecular:407.83YLT205
CAS:YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Fórmula:C16H12BrClN4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:471.78MPT0B214
CAS:MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.Fórmula:C20H20N2O5Cor e Forma:SolidPeso molecular:368.38PD-1/PD-L1-IN-29
CAS:PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.Fórmula:C26H24N2O6Cor e Forma:SolidPeso molecular:460.48MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Fórmula:C21H24N4O3Cor e Forma:SolidPeso molecular:380.44BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Fórmula:C20H21N5OPureza:99.71%Cor e Forma:SolidPeso molecular:347.41RIP1 kinase inhibitor 6
CAS:RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1Fórmula:C19H18F2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:360.35CCT373566
CAS:CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Fórmula:C26H29ClF2N6O3Cor e Forma:SolidPeso molecular:547(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Fórmula:C18H18O4Pureza:98.91% - 99.42%Cor e Forma:SolidPeso molecular:298.33Apoptotic agent-3
CAS:"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Fórmula:C31H21N5OSCor e Forma:SolidPeso molecular:511.6STAT3-IN-11
CAS:STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Fórmula:C11H9Br4N3O2Pureza:98.22%Cor e Forma:SolidPeso molecular:534.82L6H21
CAS:L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Fórmula:C18H18O4Pureza:99.26%Cor e Forma:SolidPeso molecular:298.33SMBA1
CAS:SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32
