Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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R1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Fórmula:C54H70N8O7S2Cor e Forma:SolidPeso molecular:1007.31AMG-424
<p>AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 and CD3E. It effectively kills cancer cells that express CD38, stimulates T cell proliferation, and reduces cytokine release. AMG-424 exhibits antitumor activity in mouse cancer models with bone marrow invasion and induces peripheral B cell depletion in cynomolgus monkeys. It is used in studies of multiple myeloma. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.</p>Cor e Forma:Odour LiquidHispaglabridin A
CAS:<p>Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].</p>Fórmula:C25H28O4Cor e Forma:SolidPeso molecular:392.49Anti-PSMA Antibody
<p>Anti-PSMA Antibody is a humanized IgG1 monoclonal antibody targeting PSMA. It serves as the antibody component of the ADC molecule ARX517.</p>Cor e Forma:Odour LiquidImmunology/Inflammation Compound Library
<p>A unique collection of xnum anti-inflammation compounds effective for high throughput screening and high content screening.</p>Cor e Forma:Odour SolidCOX-2-IN-52
<p>COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. It can suppress the release of NO in cells, exhibiting anti-inflammatory properties. COX-2-IN-52 offers high gastrointestinal safety and is suitable for research on oral anti-inflammatory drugs.</p>Fórmula:C16H13IN4O4S2Cor e Forma:SolidPeso molecular:516.333MTvkPABC-P5
<p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>Fórmula:C52H73N11O14Cor e Forma:SolidPeso molecular:1076.2Chemokine Inhibitor Library
<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidHPPD-IN-1
<p>HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing</p>Fórmula:C12H6F3NO4Cor e Forma:SolidPeso molecular:285.18Anti-inflammatory agent 58
<p>Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB</p>Cor e Forma:Odour SolidCbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Cor e Forma:Odour SolidSchisanchinin D
CAS:<p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>Fórmula:C23H30O6Cor e Forma:SolidPeso molecular:402.487Transcription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Cor e Forma:Odour SolidClazakizumab
CAS:<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Cor e Forma:LiquidC12-rrw-NH2
<p>C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.</p>Fórmula:C35H58N10O5Cor e Forma:SolidPeso molecular:698.9STING agonist-13
CAS:<p>STING agonist-13 boosts cancer immunity by activating STING pathway, reducing tumors, and enhancing immune memory.</p>Fórmula:C45H53N15O7Cor e Forma:SolidPeso molecular:916Post-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Cor e Forma:Odour SolidBiotin-labeled ODN 1018 sodium
<p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>Cor e Forma:Odour SolidNrf2/HO-1 activator 3
<p>Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.</p>Fórmula:C27H26N2O6Cor e Forma:SolidPeso molecular:474.51JAB-BX102
<p>JAB-BX102 is a human monoclonal antibody (mAb) that targets NT5E/CD73. It is applicable in research studies involving breast cancer, pancreatic cancer, prostate cancer, and other cancers.</p>Cor e Forma:Odour LiquidhCYP1B1-IN-1
<p>hCYP1B1-IN-1 (compound B18) is an inhibitor of hCYP1B1 with an IC50 value of 3.6 nM and also acts as an antagonist of the Aryl Hydrocarbon Receptor.</p>Fórmula:C18H14ClF3O3Cor e Forma:SolidPeso molecular:370.75Inhibitor Library
<p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Cor e Forma:Odour SolidPascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:147.18 kDaNLRP3 modulators 1
CAS:<p>Compound 107 (WO2017184746A1) is a potent NLRP3 modulator, useful for studying diseases linked to NLRP3 activity.</p>Fórmula:C17H18N6OCor e Forma:SolidPeso molecular:322.372AChE-IN-82
<p>AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.</p>Fórmula:C21H18N4O5S2Cor e Forma:SolidPeso molecular:470.52L-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Fórmula:C38H64N8O13Cor e Forma:SolidPeso molecular:840.973NVP-DKY709
CAS:<p>NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.</p>Fórmula:C25H27N3O3Pureza:99%Cor e Forma:SolidPeso molecular:417.5Antibacterial agent 207
<p>Antibacterialagent 207 (Compound Ru1) exhibits antibacterial activity against Staphylococcus aureus with a MIC of 1 μg/mL and a low resistance frequency. It disrupts bacterial cell membranes and promotes the production of reactive oxygen species (ROS) within the bacteria.</p>Fórmula:C61H56F12N8O3P2RuPeso molecular:1340.28024STING-IN-14
CAS:<p>STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.</p>Fórmula:C46H43F2N11O5Cor e Forma:SolidPeso molecular:867.901Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidNeuroprotective agent 8
<p>Neuroprotective agent 8 (compound AA-9) is an orally active neuroprotective agent that functions through antioxidant stress reduction and anti-inflammatory mechanisms. In a rat model of MCAO ischemic stroke, it activates PGC-1α and inhibits the NLRP3 inflammasome.</p>Cor e Forma:Odour SolidROS inducer 8
<p>ROS inducer 8 (Compound 11g) acts as an inhibitor of glutathione (GSH) and promotes the accumulation of reactive oxygen species (ROS) in Enterococcus faecalis, exhibiting antibacterial properties. It is capable of disrupting biofilms and inhibiting S. aureus and E. faecalis with minimum inhibitory concentrations (MICs) of 8 μg/mL and 2 μg/mL, respectively, demonstrating a post-antibiotic effect. Additionally, ROS inducer 8 shows low hemolytic toxicity on sheep red blood cells with an HC50 greater than 1280 μg/mL.</p>Fórmula:C26H31FN6O6Cor e Forma:SolidPeso molecular:542.56Keap1-Nrf2-IN-25
<p>Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor with an IC50 of 0.55 μM and exhibits a Keap1 binding affinity (Kd of 0.50 μM). This compound activates Nrf2, reducing reactive oxygen species (ROS) and pro-inflammatory cytokines (IL-1β, IL-6). Additionally, Keap1-Nrf2-IN-25 provides protective effects against DSS-induced colitis.</p>Fórmula:C25H28N2O6SCor e Forma:SolidPeso molecular:484.5658-Nitroguanine
CAS:<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Fórmula:C5H4N6O3Cor e Forma:SolidPeso molecular:196.12STING agonist-3 trihydrochloride
<p>STING agonist-3 is a selective, non-nucleotide small-molecule with anti-tumor properties and potential in cancer therapy.</p>Fórmula:C37H45Cl3N12O6Pureza:98%Cor e Forma:SolidPeso molecular:860.19IL-1β-IN-1
CAS:<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Fórmula:C22H34O2Cor e Forma:SolidPeso molecular:330.5BR102910
CAS:<p>BR102910: Selective FAP inhibitor, features 4-thiazolecarboxamide with cyano-difluoro-pyrrolidine and dichlorophenyl elements.</p>Fórmula:C18H14Cl2F2N4O2SPureza:97%Cor e Forma:SolidPeso molecular:459.3Cyclo(L-Pro-L-Val)
CAS:<p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>Fórmula:C10H16N2O2Pureza:98.18%Cor e Forma:SolidPeso molecular:196.25Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Fórmula:C42H47ClO23Cor e Forma:SolidPeso molecular:955.26Isuventatug
CAS:<p>Isuventatug is a monoclonal antibody that targets human MICA (MHC I chain-related molecule A) and MICB (MHC I chain-related molecule B). By binding to MICA and MICB, Isuventatug modulates the interaction between immune cells and tumor cells, exhibiting anti-tumor activity. This compound holds potential for research in cancer immunotherapy.</p>Cor e Forma:LiquidSTING modulator-5
CAS:<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Fórmula:C43H45F4N11O5Cor e Forma:SolidPeso molecular:871.88PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Cor e Forma:Odour SolidROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Fórmula:C24H23F2I2N3PtCor e Forma:SolidPeso molecular:840.354'-hydroxy Flurbiprofen
CAS:<p>4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.</p>Fórmula:C15H13FO3Cor e Forma:SolidPeso molecular:260.264PROTAC cGAS degrader-1
<p>PROTAC cGAS degrader-1 (Compound TH35) is a potent and selective cGAS PROTAC degrader, exhibiting DC50 values of 0.9 μM in THP-1 cells and 4.6 μM in RAW 264.7 cells. It effectively inhibits the activation of cGAS signaling induced by dsDNA. PROTAC cGAS degrader-1 also demonstrates anti-inflammatory properties, making it suitable for research into cGAS-related inflammatory diseases. (Pink: cGAS inhibitor; Black: Linker; Blue: E3 ligase ligand)</p>Fórmula:C36H33Cl2N7O5Cor e Forma:SolidPeso molecular:714.6Exosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidISD Control sodium
ISD (interferon stimulatory DNA) Control sodium is a non-immunostimulatory single-stranded oligonucleotide with a sequence identical to its double-stranded counterpart, ISD.LAG-3 cyclic peptide inhibitor 12
<p>LAG-3cyclic peptide inhibitor 12 (Cyclic peptide 12) is an inhibitor of LAG-3, exhibiting an IC50 of 4.45 μM and a Ki of 2.66 µM.</p>Fórmula:C44H67N13O11S3Cor e Forma:SolidPeso molecular:1050.28Nurulimab
CAS:<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Pureza:95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:LiquidBasiliximab
CAS:<p>Basiliximab: chimeric IgG1 antibody inhibiting interleukin-2 receptor, used for kidney transplant immunosuppression.</p>Pureza:SDS-PAGE:94.1%;SEC-HPLC:95.3%Cor e Forma:LiquidPeso molecular:144.01 kDa(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA
CAS:<p>(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA ((6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-coenzyme A) acts as an NLRX1 modulator. This compound shows potential for research into immune and metabolism-related diseases.</p>Fórmula:C45H70N7O17P3SCor e Forma:SolidPeso molecular:1106.06MEDI-7836
<p>MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the interleukin-13 (interleukin-13 receptor) receptor. It shows potential for research into diseases associated with inflammation.</p>Cor e Forma:Odour LiquidNOD1 antagonist-1
<p>NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively.</p>Fórmula:C24H32N4O2SPeso molecular:440.2246cGAS-IN-3
<p>cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.</p>Fórmula:C21H20Cl2F2N4O2Peso molecular:468.093142,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
CAS:<p>2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs of</p>Fórmula:C20H27Cl3O12Cor e Forma:SolidPeso molecular:565.78Fraxinellone analog 1
<p>Fraxinellone analog 1 (compound 2) is an effective and rapid activator of the Nrf2-mediated antioxidative defense system, providing protection against glutamate-mediated excitotoxicity. It induces the expression of antioxidative genes Gpx4, Sod1, and Nqo1. Additionally, Fraxinellone analog 1 exerts neuroprotective effects and modulates oxidative stress and inflammation, making it suitable for research on neurodegenerative diseases.</p>Cor e Forma:Odour SolidCOX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Cor e Forma:Odour SolidDEPMPO-biotin
CAS:<p>DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.</p>Fórmula:C24H42N5O8PSCor e Forma:SolidPeso molecular:591.66BMS-986251
CAS:<p>BMS-986251: Oral RORγt inverse agonist, EC50 12 nM; inhibits IL-17 (EC50 24 nM); effective in mouse psoriasis models.</p>Fórmula:C30H29F8NO5SCor e Forma:SolidPeso molecular:667.612-(Phosphonooxy)benzoic acid
CAS:<p>2-(Phosphonooxy)benzoic acid (Fosfosal), used as the anti-inflammatory agent, has the anti-bacterial effect.</p>Fórmula:C7H7O6PPureza:99.83%Cor e Forma:SolidPeso molecular:218.1Pam3CSK4-Biotin
CAS:<p>Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.</p>Fórmula:C103H192N14O17S2Pureza:98%Cor e Forma:SolidPeso molecular:1962.85FLY26
<p>FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.</p>Fórmula:C22H23N5O3Cor e Forma:SolidPeso molecular:405.18009Nogapendekin alfa inbakicept
CAS:Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).Cor e Forma:SolidNT-0249
CAS:<p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>Fórmula:C22H28N5NaO4SPureza:98.11%Cor e Forma:SoildPeso molecular:481.54NLRP3-IN-46
<p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>Cor e Forma:Odour SolidiNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Cor e Forma:Odour SolidDiprovocim-X
<p>Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.</p>Fórmula:C66H83N7O10Cor e Forma:SolidPeso molecular:1134.41Ripertamab
CAS:<p>Ripertamab (SCT-400) is a recombinant human-mouse chimeric monoclonal antibody that targets CD20 and is cytotoxic.</p>Pureza:97.8% (SEC-HPLC) - 97.8% (SEC-HPLC)Cor e Forma:LiquidTri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>Fórmula:C78H125N7O36Cor e Forma:SolidPeso molecular:1736.851-Heptadecanoyl-rac-glycerol
CAS:<p>1-Heptadecanoyl-rac-glycerol, a monoacylglycerol with heptadecanoic acid, combats various bacteria and is found in T. africana, I. sonorae, and wheat bran.</p>Fórmula:C20H40O4Cor e Forma:SolidPeso molecular:344.536Histone Modification Compound Library
<p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidKTX-951
CAS:KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as anticancer agent.Fórmula:C46H52F2N8O6Cor e Forma:SolidPeso molecular:850.95CNTO-6785
CNTO-6785 is a humanized monoclonal antibody inhibitor that targets interleukin-17A (IL-17A). It holds potential for research in chronic obstructive pulmonary disease (COPD).Cor e Forma:Odour LiquidMepolizumab
CAS:<p>Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.</p>Pureza:98% - 98%Cor e Forma:LiquidPS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Fórmula:C17H13Cl3N4OPureza:98%Cor e Forma:SolidPeso molecular:395.67BuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Cor e Forma:Odour SolidFITC-labeled ODN 2088 sodium
<p>FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization</p>Cor e Forma:Odour SolidDithianon
CAS:Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.Fórmula:C14H4N2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:296.32Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Fórmula:C18H33Cl2CuN3O3Cor e Forma:Colorless Crystalline Slightly Hygroscopic Solid CoaPeso molecular:473.93Itolizumab
CAS:<p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.82 kDaPterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.424TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H9ClO2S2Cor e Forma:SolidPeso molecular:248.75Guignardone L
CAS:<p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>Fórmula:C17H24O4Cor e Forma:SolidPeso molecular:292.37Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Fórmula:C19H14ClNO4Peso molecular:355.06114Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Cor e Forma:LiquidPeso molecular:150 kDaE7766 diammonium salt
CAS:<p>E7766 diammonium salt, a macrocycle-bridged STING agonist, exhibits a dissociation constant (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor</p>Fórmula:C24H32F2N12O8P2S2Cor e Forma:SolidPeso molecular:780.66P2X7-IN-2 TFA
P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.Fórmula:C24H22F7N3O4Cor e Forma:SolidPeso molecular:549.44Compstatin TFA
<p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>Fórmula:C68H100F3N23O19S2Cor e Forma:SolidPeso molecular:1664.79Xanthine oxidase-IN-12
<p>Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally</p>Pureza:98%Cor e Forma:Odour Solid19-epi-Scholaricine
CAS:<p>19-epi-Scholaricine: indole alkaloid, taken orally, reduces collagen fibrosis, boosts SOD.</p>Fórmula:C20H24N2O4Cor e Forma:SolidPeso molecular:356.42Guretolimod hydrochloride
<p>Guretolimod hydrochloride acts as an agonist for Toll-like receptor 7 (TLR7) [1].</p>Fórmula:C24H35ClF3N5O4Cor e Forma:SolidPeso molecular:550.015(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472NLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Cor e Forma:Odour SolidMAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Cor e Forma:Odour SolidTLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Fórmula:C54H63N9O16Cor e Forma:SolidPeso molecular:1094.13Prostaglandin D synthase
CAS:<p>Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type prostaglandin D synthase (L-PGDS) is found in human coronary atherosclerotic plaques and can be detected in human serum.</p>Cor e Forma:SolidS7
CAS:<p>S7, an IL-6 receptor antagonist, prevents the interaction between IL-6 and IL-6R, thereby inhibiting angiogenesis and tumor growth [1].</p>Fórmula:C37H70N10O10Cor e Forma:SolidPeso molecular:815.01CLIP (86-100)
CAS:Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.Fórmula:C72H128N20O19S3Pureza:98%Cor e Forma:SolidPeso molecular:1674.1PIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:SolidCNTO4088
CNTO4088 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis.Cor e Forma:Odour LiquidBivalirudin TFA
CAS:<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Fórmula:C98H138N24O33·C2HF3O2Cor e Forma:SolidPeso molecular:2294.34Interleukin II (60-70)
Interleukin 2 (IL-2) peptide: NH2-LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH, MW 1373.7, immune cytokine.Fórmula:C68H104N14O14S1Pureza:98%Cor e Forma:SolidPeso molecular:1373.7SDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Fórmula:C19H11ClF6N2O2Cor e Forma:SolidPeso molecular:448.75PROTAC IRAK4 degrader-3
CAS:PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.Fórmula:C57H68FN11O8SCor e Forma:SolidPeso molecular:1086.3Biotinoyl tripeptide-1
CAS:<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Fórmula:C24H38N8O6SPureza:98%Cor e Forma:SolidPeso molecular:566.67Sartorypyrone D
CAS:<p>Sartorypyrone D, from N. fischeri, inhibits NFRD (1.7 μM) and NADH oxidase (3 μM), and fights Gram-positive bacteria.</p>Fórmula:C26H38O4Cor e Forma:SolidPeso molecular:414.586BMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Cor e Forma:Odour LiquidKTX-955
CAS:<p>KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].</p>Fórmula:C46H51F3N8O7Cor e Forma:SolidPeso molecular:884.94Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34) linker reduces inflammation by inhibiting TLR4 in cells, shown effective in mouse endotoxemia and enterocolitis.</p>Fórmula:C84H134N10O39Cor e Forma:SolidPeso molecular:1908.01Rucosopasem manganese
CAS:<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Fórmula:C27H45MnN5O4Cor e Forma:SolidPeso molecular:558.626Bengamide B
CAS:<p>Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.</p>Fórmula:C32H58N2O8Cor e Forma:SolidPeso molecular:598.81Endoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidAMY-101
CAS:<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Fórmula:C83H117N23O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1789.111-Ethoxycarbonyl-β-carboline
CAS:<p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>Fórmula:C28H23N4O4Cor e Forma:SolidPeso molecular:479.516Arginase inhibitor 9
<p>Arginase inhibitor9 (Compound 12a) is a type of arginase enzyme inhibitor with IC50 values of 9 μM for bovine and 55 μM for human arginase I. It also exhibits antioxidant activity by scavenging free radicals. Moreover, Arginase inhibitor9 effectively regulates collagen and procollagen levels, thereby exerting an anti-fibrotic effect.</p>Fórmula:C13H11NO4SCor e Forma:SolidPeso molecular:277.3QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Cor e Forma:Odour Liquid(±)11(12)-EET
CAS:<p>(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidAβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Fórmula:C28H31N3O4Cor e Forma:SolidPeso molecular:473.56DA-E 5090
CAS:<p>DA-E 5090, an active metabolite of E 5090, inhibits IL-1 production in human monocytes.</p>Fórmula:C17H18O4Pureza:98%Cor e Forma:SolidPeso molecular:286.32β-Interleukin II (44-56)
β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.Fórmula:C68H113N19O19Pureza:98%Cor e Forma:SolidPeso molecular:1500.74Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Cor e Forma:Odour SolidEftilagimod alfa
CAS:<p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>Cor e Forma:LiquidMik-β-1
Mik-Beta-1 is a human IgG1-kappa monoclonal antibody targeting IL2RB. For isotype control, refer to Human IgG1 kappa, Isotype Control. Mik-Beta-1 is applicable in research related to the prevention of allograft rejection.Cor e Forma:Odour LiquidGuretolimod
CAS:<p>Guretolimod is a Toll-like receptor 7 (TLR7) agonist.</p>Fórmula:C24H34F3N5O4Cor e Forma:SolidPeso molecular:513.562CP-289
CAS:<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Fórmula:C30H35ClN2O2Pureza:99.97%Cor e Forma:SoildPeso molecular:491.06Ieramilimab
<p>Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity for the study of malignant tumors.</p>Pureza:96.4% (SDS-PAGE); 97.8% (SEC-HPLC) - 96.4% (SDS-PAGE); 97.8% (SEC-HPLC)Cor e Forma:Odour LiquidDectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:LiquidAntiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Cor e Forma:Odour SolidAntibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Fórmula:C42H54BrClN2O4Cor e Forma:SolidPeso molecular:766.246TGF-β/Smad Compound Library
<p>A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidMJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Cor e Forma:Odour SolidR-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54Isoxaben
CAS:<p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>Fórmula:C18H24N2O4Pureza:98.84%Cor e Forma:SolidPeso molecular:332.39Tetrachlorohydroquinone
CAS:<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Fórmula:C6H2Cl4O2Cor e Forma:SolidPeso molecular:247.89MCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Fórmula:C45H52ClN7O13Pureza:98%Cor e Forma:SolidPeso molecular:934.39CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Fórmula:C17H20N4O3SCor e Forma:SolidPeso molecular:360.43Clivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:145.42 kDaC6 L-threo Ceramide (d18:1/6:0)
CAS:<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Fórmula:C24H47NO3Cor e Forma:SolidPeso molecular:397.63NLRP3-IN-76
<p>NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).</p>Cor e Forma:Odour SolidiE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Fórmula:C12H23Cl2N3O7Cor e Forma:SolidPeso molecular:391.09131NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Fórmula:C62H50N4O4SCor e Forma:SolidPeso molecular:947.15PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Cor e Forma:SolidPeso molecular:953.06Allyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Fórmula:C4H8S3Cor e Forma:SolidPeso molecular:152.3Polyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Fórmula:(C10H13N4O8P)xCor e Forma:Solidα-Glucosidase/NLRP3-IN-1
α-Glucosidase/NLRP3-IN-1 (Compound 8) acts as a dual inhibitor targeting both α-glucosidase and NLRP3. It features an IC50 value of 6.6 μM for α-glucosidase and inhibits NLRP3 across multiple cell lines at a concentration of 100 μM. This compound demonstrates neuroprotective and antidiabetic properties, making it suitable for related research.Fórmula:C38H54O4Cor e Forma:SolidPeso molecular:574.83ZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Cor e Forma:Odour LiquidZuberitamab
CAS:<p>Zuberitamab (HS006) is a monoclonal antibody targeting CD20, utilized in cancer research, notably in diffuse large B-cell lymphoma [1].</p>Cor e Forma:LiquidKYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Fórmula:C22H19FN6Pureza:98.35%Cor e Forma:SolidPeso molecular:386.43LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Fórmula:C121H206N38O30Pureza:99.88%Cor e Forma:SolidPeso molecular:2673.17cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Fórmula:C20H24N10O13P2·2NaCor e Forma:SoildPeso molecular:720.39Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Cor e Forma:SolidFM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Cor e Forma:Odour LiquidHPK1-IN-58
HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.Fórmula:C26H30N8OCor e Forma:SolidPeso molecular:470.25426Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Fórmula:C19H29NO3Pureza:98%Cor e Forma:SolidPeso molecular:319.44Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Fórmula:C23H34O9Cor e Forma:SolidPeso molecular:454.516COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Fórmula:C27H26N6OS2Pureza:98%Cor e Forma:SolidPeso molecular:514.66Phytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Fórmula:C18H13ClF3N3O2SCor e Forma:SolidPeso molecular:427.83Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Fórmula:C27H33N3O2Pureza:99.58% - 99.88%Cor e Forma:SoildPeso molecular:431.57PROTAC STING Degrader-1
CAS:<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Fórmula:C34H33N7O10Cor e Forma:SolidPeso molecular:699.67TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Fórmula:C53H63N11O10Cor e Forma:SolidPeso molecular:1014.14NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Fórmula:C16H11FN2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:314.33DDX3-IN-1
CAS:DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.Fórmula:C17H17N5OCor e Forma:SolidPeso molecular:307.35CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Cor e Forma:SolidPeso molecular:305.143-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS:<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Fórmula:C28H24ClN3O6Pureza:99.9%Cor e Forma:SolidPeso molecular:533.96PSB-24000
<p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>Cor e Forma:Odour SolidAnti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Cor e Forma:Odour LiquidTimosaponin E2
CAS:Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].Fórmula:C46H78O20Cor e Forma:SolidPeso molecular:951.1Photosensitizer-4
Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.Cor e Forma:Odour Solid[12]-Dehydrogingerdione
CAS:<p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>Fórmula:C23H34O4Pureza:98%Cor e Forma:SolidPeso molecular:374.51Dovanvetmab
CAS:<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Cor e Forma:LiquidPROTAC STING degrader-4
<p>PROTACSTING degrader-4 is a covalent STINGPROTAC degrader free of nitro groups, exhibiting a DC50 of 3.23 μM. It effectively inhibits STING and its downstream signaling pathways, including p-TBK1 and p-NF-κB (p-P65), as well as immune-inflammatory cytokines. Additionally, PROTACSTING degrader-4 mitigates renal and blood inflammation in mouse models of Cisplatin-induced acute kidney injury (AKI).</p>Fórmula:C39H42Cl2N8O9Cor e Forma:SolidPeso molecular:836.24518Inflexuside A
CAS:<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Fórmula:C26H42O9Cor e Forma:SolidPeso molecular:498.61Aminopicoline
CAS:<p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H8N2Cor e Forma:White To Pale Yellow Solid FlakesPeso molecular:108.14Cyclic-di-GMP disodium
CAS:Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.Fórmula:C20H22N10Na2O14P2Pureza:98.98% - 99.93%Cor e Forma:SolidPeso molecular:734.381-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Fórmula:C13H18O3Cor e Forma:SolidPeso molecular:222.2802Balekafusp alfa
CAS:Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.Cor e Forma:LiquidObinutuzumab
CAS:<p>Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.</p>Pureza:98.00% - 98.9% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.6 kDaPSMA-IN-3
<p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>Fórmula:C43H50FN7O15Cor e Forma:SolidPeso molecular:923.89Romilkimab
CAS:<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Cor e Forma:LiquidQX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Cor e Forma:Odour LiquidSN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Fórmula:C129H230N36O29S·XCF3COOHCor e Forma:SolidPeso molecular:2781.5 (free base)EPI-589
CAS:<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Fórmula:C14H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:265.31Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Cor e Forma:LiquidNC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Pureza:98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:Odour LiquidFITC-labeled ODN 1585 sodium
<p>FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-</p>Cor e Forma:Odour SolidNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Cor e Forma:Odour SolidMifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Fórmula:C59H108N6NaO19PPureza:98%Cor e Forma:SolidPeso molecular:1259.48LY2409881
CAS:<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Fórmula:C24H29ClN6OSCor e Forma:SolidPeso molecular:485.05CFT7455
CAS:<p>CFT7455: orally active anti-cancer drug, targets cereblon E3 ligase (Kd 0.9 nM), degrades IKZF1/Ikaros, IKZF3/Aiolos.</p>Fórmula:C28H27N3O4Pureza:97.93%Cor e Forma:SolidPeso molecular:469.53TLR7 agonist 17
CAS:TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Fórmula:C25H37N7O3Cor e Forma:SolidPeso molecular:483.61NLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Fórmula:C27H28N2O4Cor e Forma:SolidPeso molecular:444.52IKZF-IN-1
<p>IKZF-IN-1 (Compound I) is a molecular glue that degrades the karos zinc finger family proteins (IKZF) IKZF 1/2/3/4 and is used as an immune modulator in cancer and viral infection research.</p>Fórmula:C26H28FN5O4Cor e Forma:SolidPeso molecular:493.53MethADP sodium salt
CAS:<p>MethADP is a specific CD73 inhibitor.</p>Fórmula:C11H17N5NaO9P2Pureza:98%Cor e Forma:SolidPeso molecular:448.223′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Fórmula:C21H22O5Cor e Forma:SolidPeso molecular:354.4CDN-A
CAS:<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Fórmula:C22H29N11O12P2Cor e Forma:SolidPeso molecular:701.48FM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Cor e Forma:Odour LiquidKeap1-Nrf2-IN-3
CAS:<p>Keap1-Nrf2-IN-3 is a KEAP1:NRF2 protein protein interaction inhibitor, and with a K d value of 2.5 nM for KEAP1 protein.</p>Fórmula:C31H34N6O3Cor e Forma:SolidPeso molecular:538.652Cryogenine
CAS:<p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>Fórmula:C26H29NO5Cor e Forma:SolidPeso molecular:435.527-Deoxy-trans-dihydronarciclasine
CAS:<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Fórmula:C14H15NO6Cor e Forma:SolidPeso molecular:293.27
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