Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(34 produtos)
- Cisteína Protease(96 produtos)
- DPP-4(20 produtos)
- Glutaminase(40 produtos)
- HIV Protease(449 produtos)
- PAI-1(25 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(53 produtos)
- Proteassoma(94 produtos)
- Protease serina(50 produtos)
- p97(14 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1044 produtos de "Proteases/Proteassoma"
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Cilastatin
CAS:<p>Cilastatin (MK0791): protects imipenem from renal breakdown; inhibits leukotriene D4 metabolism.</p>Fórmula:C16H26N2O5SPureza:97.76% - 99.71%Cor e Forma:SolidPeso molecular:358.45Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Cor e Forma:White To Off-White SolidPeso molecular:435.28Thiamine disulfide
CAS:<p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>Fórmula:C24H34N8O4S2Pureza:99.81%Cor e Forma:CoaPeso molecular:562.71Darunavir Ethanolate
CAS:<p>Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Fórmula:C29H43N3O8SPureza:99.84% - 99.86%Cor e Forma:SolidPeso molecular:593.74Dabigatran Etexilate Mesylate
CAS:<p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>Fórmula:C34H41N7O5·CH4O3SPureza:99.91%Cor e Forma:SolidPeso molecular:723.84Omarigliptin
CAS:<p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>Fórmula:C17H20F2N4O3SPureza:99.68% - 99.77%Cor e Forma:SolidPeso molecular:398.43Y-29794 Tosylate
CAS:<p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>Fórmula:C30H42N2O4S3Pureza:99.86%Cor e Forma:SolidPeso molecular:590.86JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Fórmula:C16H16N4O2S2Pureza:99.46% - 99.62%Cor e Forma:SolidPeso molecular:360.45(S,S)-TAPI-1
CAS:<p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>Fórmula:C26H37N5O5Cor e Forma:SolidPeso molecular:499.6Darunavir
CAS:<p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Fórmula:C27H37N3O7SPureza:99.67% - 99.76%Cor e Forma:White Amorphous SolidPeso molecular:547.66Coblopasvir dihydrochloride
CAS:<p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>Fórmula:C41H52Cl2N8O8Pureza:99.33%Cor e Forma:SolidPeso molecular:855.81Belnacasan
CAS:<p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>Fórmula:C24H33ClN4O6Pureza:96.53% - 99.5%Cor e Forma:SolidPeso molecular:508.99Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Fórmula:C16H10ClF3N2OPureza:99.86%Cor e Forma:SolidPeso molecular:338.71KKI-5 acetate(97145-43-2 free base)
<p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>Fórmula:C37H59N11O11Pureza:99.44%Cor e Forma:SolidPeso molecular:833.95Tris(4-aminophenyl)methane
CAS:<p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>Fórmula:C19H19N3Pureza:95.73%Cor e Forma:Beige Solid CrystallinePeso molecular:289.37Mericitabine
CAS:<p>Mericitabine (R-7128) is an HCV inhibitor that terminates RNA chains, halting replication.</p>Fórmula:C18H26FN3O6Pureza:97.77% - 98.54%Cor e Forma:SolidPeso molecular:399.41XMD8-87
CAS:<p>XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.</p>Fórmula:C24H27N7O2Pureza:98.05% - 99.89%Cor e Forma:SolidPeso molecular:445.52L-Albizziin
CAS:<p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>Fórmula:C4H9N3O3Pureza:99.98%Cor e Forma:White PowderPeso molecular:147.13Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26NBD-557
CAS:<p>NBD-557 is a potentially HIV-1 inhibitor.</p>Fórmula:C17H24BrN3O2Pureza:99.52%Cor e Forma:SolidPeso molecular:382.3Alvelestat
CAS:<p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>Fórmula:C25H22F3N5O4SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:545.53Avatrombopag
CAS:<p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>Fórmula:C29H34Cl2N6O3S2Pureza:99.01% - 99.63%Cor e Forma:SolidPeso molecular:649.65SU 4942
CAS:<p>SU-4942 is a modulator of tyrosine kinase signaling.</p>Fórmula:C15H10BrNOPureza:99% - 99.32%Cor e Forma:SolidPeso molecular:300.157-Amino-4-methylcoumarin-3-acetic acid
CAS:<p>7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) is more suitable as a substrate for enteropeptidase than GD(4)K-NA.</p>Fórmula:C12H11NO4Pureza:98.38%Cor e Forma:SolidPeso molecular:233.22S 3304
CAS:<p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>Fórmula:C24H20N2O4S2Pureza:98.09%Cor e Forma:SolidPeso molecular:464.56HZ-1157
CAS:<p>HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.</p>Fórmula:C12H16N4OPureza:98.23%Cor e Forma:SolidPeso molecular:232.28BMS-707035
CAS:<p>BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.</p>Fórmula:C17H19FN4O5SPureza:99.78%Cor e Forma:SolidPeso molecular:410.42Tenofovir alafenamide
CAS:<p>Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.</p>Fórmula:C21H29N6O5PPureza:99.68% - 99.81%Cor e Forma:SolidPeso molecular:476.47Velpatasvir
CAS:<p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>Fórmula:C49H54N8O8Pureza:99.17% - 99.83%Cor e Forma:SolidPeso molecular:883Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。</p>Fórmula:C40H43N7O7SPureza:99.72%Cor e Forma:SolidPeso molecular:765.88XMD16-5
CAS:<p>XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.</p>Fórmula:C23H24N6O2Pureza:98.89% - 99.98%Cor e Forma:SolidPeso molecular:416.48Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Fórmula:C22H29FN3O9PPureza:99.77% - 99.82%Cor e Forma:SolidPeso molecular:529.454-Butylresorcinol
CAS:<p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>Fórmula:C10H14O2Pureza:98.64% - ≥95%Cor e Forma:Light Beige Solid PowderPeso molecular:166.22Odanacatib
CAS:<p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>Fórmula:C25H27F4N3O3SPureza:98.53% - 99.53%Cor e Forma:SolidPeso molecular:525.56Daclatasvir dihydrochloride
CAS:<p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>Fórmula:C40H52Cl2N8O6Pureza:99.67%Cor e Forma:SolidPeso molecular:811.8Ximelagatran
CAS:<p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>Fórmula:C24H35N5O5Pureza:95.48% - 99.60%Cor e Forma:SolidPeso molecular:473.57TAPI-1 trifluoroacetate (163847-77-6(free base))
<p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>Fórmula:C28H38F3N5O7Pureza:98.06%Cor e Forma:SolidPeso molecular:613.62Elbasvir
CAS:<p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>Fórmula:C49H55N9O7Pureza:98.95% - 99.85%Cor e Forma:SolidPeso molecular:882.02Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Fórmula:C20H23BCl2N2O9Pureza:98.37% - >99.99%Cor e Forma:SolidPeso molecular:517.12Tegobuvir
CAS:<p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>Fórmula:C25H14F7N5Pureza:99.21%Cor e Forma:SolidPeso molecular:517.4Voxilaprevir
CAS:<p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>Fórmula:C40H52F4N6O9SPureza:99.83% - 99.93%Cor e Forma:SolidPeso molecular:868.93Grazoprevir
CAS:<p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>Fórmula:C38H50N6O9SPureza:99.36% - >99.99%Cor e Forma:SolidPeso molecular:766.9Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Fórmula:C30H37N5O13Pureza:98.20%Cor e Forma:White PowderPeso molecular:675.644-Phenoxybenzylamine
CAS:<p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>Fórmula:C13H13NOPureza:97.26%Cor e Forma:SolidPeso molecular:199.25(R)-MG-132
CAS:<p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>Fórmula:C26H41N3O5Pureza:98.45%Cor e Forma:SolidPeso molecular:475.62Dolutegravir sodium
CAS:<p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>Fórmula:C20H18F2N3NaO5Pureza:98% - 99.46%Cor e Forma:SolidPeso molecular:441.36Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Fórmula:C37H59N9O18Pureza:99.47%Cor e Forma:SolidPeso molecular:917.91CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Cor e Forma:SolidPeso molecular:397.47Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Fórmula:C29H28F4N4O4Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:572.55PTACH
CAS:<p>PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).</p>Fórmula:C20H26N2O2S2Pureza:87.44% - 99.74%Cor e Forma:SolidPeso molecular:390.56
