Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(36 produtos)
- Cisteína Protease(110 produtos)
- DPP-4(24 produtos)
- Glutaminase(44 produtos)
- HIV Protease(498 produtos)
- PAI-1(26 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(54 produtos)
- Proteassoma(90 produtos)
- Protease serina(51 produtos)
- p97(15 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1011 produtos de "Proteases/Proteassoma"
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AGPS-IN-2i
CAS:AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Fórmula:C18H17F2N3O2Pureza:98.92%Cor e Forma:SolidPeso molecular:345.34Ref: TM-T69685
1mg74,00€5mg188,00€10mg311,00€25mg525,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)154,00€PG-116800
CAS:PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.Fórmula:C24H27N3O7SPureza:98.03% - 99.66%Cor e Forma:SolidPeso molecular:501.55CPA inhibitor
CAS:CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.Fórmula:C18H19NO4Pureza:99.94%Cor e Forma:SolidPeso molecular:313.35Ref: TM-T10876
1mg57,00€5mg125,00€10mg163,00€25mg278,00€50mg405,00€100mgA consultar1mL*10mM (DMSO)138,00€JNJ-10311795
CAS:JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.Fórmula:C40H35N2O6PPureza:97.43%Cor e Forma:SolidPeso molecular:670.69BAY-43-9695
CAS:BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.Fórmula:C22H25N3O4SPureza:99.50% - 99.98%Cor e Forma:SolidPeso molecular:427.52(2RS)-FPMPA
CAS:(2RS)-FPMPA（FPMPA） has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).Fórmula:C9H13FN5O4PPureza:99.9% - >99.99%Cor e Forma:SolidPeso molecular:305.2CP-544439
CAS:CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.Fórmula:C18H19FN2O6SPureza:95.02% - 98.66%Cor e Forma:SolidPeso molecular:410.42TG-2-IN-1
CAS:TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].Fórmula:C8H13ClN2OSPureza:98.43%Cor e Forma:SolidPeso molecular:220.72Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Fórmula:C22H27N5O5Pureza:98.01% - 98.37%Cor e Forma:SolidPeso molecular:441.48BMS-929075
CAS:BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokineticFórmula:C31H24F2N4O3Pureza:99.81% - 99.94%Cor e Forma:SolidPeso molecular:538.54Ref: TM-T26863
1mg172,00€5mg432,00€10mg618,00€25mg973,00€50mg1.333,00€100mg1.791,00€500mg3.529,00€1mL*10mM (DMSO)538,00€TY-51469
CAS:TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).Fórmula:C20H15FN2O6S4Pureza:99.65%Cor e Forma:SolidPeso molecular:526.6MMP-2/MMP-9 Inhibitor I
CAS:MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.
Fórmula:C21H19NO4SPureza:99.74%Cor e Forma:SolidPeso molecular:381.44VRK-IN-1
CAS:VRK-IN-1 is a potent and selective inhibitor of cowpox-associated kinase 1 (VRK1), which can be used in the study of neurological disorders.Fórmula:C18H11F4NO2Pureza:99.18% - 99.25%Cor e Forma:SolidPeso molecular:349.28Ref: TM-T35863
1mg103,00€5mg236,00€10mg379,00€25mg750,00€50mg1.130,00€100mg1.510,00€200mg2.062,00€1mL*10mM (DMSO)259,00€2'-C-Methyladenosine
CAS:2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.Fórmula:C11H15N5O4Pureza:99.85%Cor e Forma:SolidPeso molecular:281.27UK-396082
CAS:UK-396082 is a TAFI inhibitor that inhibits Carboxypeptidase B and can be used in the study of thrombosis, atherosclerosis, cancer and fibrotic conditions.Fórmula:C12H21N3O2Pureza:99.89%Cor e Forma:SolidPeso molecular:239.31Setrobuvir
CAS:Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension withFórmula:C25H25FN4O6S2Pureza:99.95% - 99.97%Cor e Forma:SolidPeso molecular:560.62Ref: TM-T28762
1mg229,00€5mg570,00€10mg812,00€25mg1.216,00€50mg1.663,00€100mg2.242,00€500mg4.494,00€1mL*10mM (DMSO)737,00€TS-021
CAS:TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.Fórmula:C17H24FN3O5SPureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:401.45MK-8325
CAS:MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailabilityFórmula:C43H54Cl2F2N8O6SiPureza:99.61%Cor e Forma:SolidPeso molecular:915.93HIV-1 integrase inhibitor 8
CAS:HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].
Fórmula:C21H24O2Pureza:98.91%Cor e Forma:SolidPeso molecular:308.41Gemigliptin
CAS:Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)Fórmula:C18H19F8N5O2Pureza:99.72%Cor e Forma:SolidPeso molecular:489.36Ref: TM-T7369
2mg38,00€5mg57,00€10mg93,00€25mg148,00€50mg245,00€100mg385,00€500mg873,00€1mL*10mM (DMSO)84,00€
