Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Triptonide
CAS:<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Fórmula:C20H22O6Pureza:99.11% - 99.64%Cor e Forma:White Crystalline PowderPeso molecular:358.39Leonurine hydrochloride
CAS:<p>Leonurine hydrochloride (SCM-198 hydrochloride) , a major alkaloid compound extracted from Leonurus japonicas Houtt.</p>Fórmula:C14H22ClN3O5Pureza:99.07%Cor e Forma:SolidPeso molecular:347.79Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Fórmula:C27H30O14Pureza:98.11% - 98.58%Cor e Forma:SolidPeso molecular:578.52palovarotene
CAS:<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Fórmula:C27H30N2O2Pureza:97.88% - 98.05%Cor e Forma:SolidPeso molecular:414.54C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Fórmula:C24H19N3O6Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:445.42SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Fórmula:C20H21FN4O2Pureza:99.42% - 99.81%Cor e Forma:SolidPeso molecular:368.4Azithromycin
CAS:<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Fórmula:C38H72N2O12Pureza:99.9% - 99.97%Cor e Forma:White To Off-White Solid CrystallinePeso molecular:748.98Silmitasertib
CAS:<p>Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).</p>Fórmula:C19H12ClN3O2Pureza:98% - 99.90%Cor e Forma:SolidPeso molecular:349.77Scriptaid
CAS:<p>Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.</p>Fórmula:C18H18N2O4Pureza:96.74% - 99.45%Cor e Forma:SolidPeso molecular:326.354E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Fórmula:C28H18N2O6Pureza:99.47%Cor e Forma:SolidPeso molecular:478.45Hemin
CAS:<p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>Fórmula:C34H32ClFeN4O4Pureza:97.169% - 99.59%Cor e Forma:Dark Purple Crystalline PowderPeso molecular:651.94β-Lapachone
CAS:<p>β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.</p>Fórmula:C15H14O3Pureza:99.76% - 99.88%Cor e Forma:SolidPeso molecular:242.27DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Cor e Forma:White SolidPeso molecular:432.46Ginsenoside Rb1
CAS:<p>Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C54H92O23Pureza:99.12% - 99.76%Cor e Forma:SolidPeso molecular:1109.29SB225002
CAS:<p>SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.</p>Fórmula:C13H10BrN3O4Pureza:98.16% - 99.85%Cor e Forma:SolidPeso molecular:352.14FC131 TFA (606968-52-9 free base)
CAS:<p>FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv</p>Fórmula:C38H48F3N11O8Pureza:99.39% - 99.67%Cor e Forma:SolidPeso molecular:843.85ATI-2341 acetate(1337878-62-2 free base)
<p>ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.</p>Fórmula:C106H182N26O27S2Pureza:97.14%Cor e Forma:SolidPeso molecular:2316.87Idelalisib
CAS:<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Fórmula:C22H18FN7OPureza:98% - 99.39%Cor e Forma:SolidPeso molecular:415.42MSX-122
CAS:<p>MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).</p>Fórmula:C16H16N6Pureza:98.31% - 98.94%Cor e Forma:SolidPeso molecular:292.34Acacetin
CAS:<p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>Fórmula:C16H12O5Pureza:96.26% - ≥95%Cor e Forma:Pale-Yellow NeedlesPeso molecular:284.26Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Fórmula:C19H21ClFN3O4SPureza:99.78% - >99.99%Cor e Forma:SolidPeso molecular:441.9Navarixin
CAS:<p>Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil</p>Fórmula:C21H23N3O5Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:397.42PD 169316
CAS:<p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>Fórmula:C20H13FN4O2Pureza:98.65%Cor e Forma:SolidPeso molecular:360.34Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Cor e Forma:SolidPeso molecular:402.66AMD 3465 hexahydrobromide
CAS:<p>AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.</p>Fórmula:C24H44Br6N6Pureza:99.39%Cor e Forma:SolidPeso molecular:896.07SB-265610
CAS:<p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>Fórmula:C14H9BrN6OPureza:99.5%Cor e Forma:SolidPeso molecular:357.16ML339
CAS:<p>ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.</p>Fórmula:C26H32ClN3O5Pureza:99.9%Cor e Forma:SolidPeso molecular:502AMD-070 hydrochloride
CAS:<p>AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.</p>Fórmula:C21H28ClN5Pureza:98.38% - 98.57%Cor e Forma:SolidPeso molecular:385.93CTCE 9908 acetate
<p>CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.</p>Fórmula:C88H151N27O25Pureza:98.47%Cor e Forma:SolidPeso molecular:1987.31MSX-127
CAS:<p>MSX-127 elicites positive response in peptide CXCR4.</p>Fórmula:C16H24N2O4Pureza:98.43%Cor e Forma:SolidPeso molecular:308.37WZ811
CAS:<p>WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).</p>Fórmula:C18H18N4Pureza:99.42% - ≥95%Cor e Forma:SolidPeso molecular:290.36Tenovin-1
CAS:<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Fórmula:C20H23N3O2SPureza:99.33%Cor e Forma:SolidPeso molecular:369.48USL311
CAS:<p>USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.</p>Fórmula:C24H34N6OPureza:98.46% - 99.56%Cor e Forma:SolidPeso molecular:422.57TAK-779
CAS:<p>TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).</p>Fórmula:C33H39ClN2O2Pureza:99.21%Cor e Forma:SolidPeso molecular:531.13Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Fórmula:C44H70O16Pureza:98% - 99.5%Cor e Forma:SolidPeso molecular:855.02JMS-17-2
CAS:<p>JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).</p>Fórmula:C25H26ClN3OPureza:98.7% - 99.44%Cor e Forma:SolidPeso molecular:419.95TC14012 acetate
<p>TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.</p>Fórmula:C92H144N34O21S2Pureza:98.33% - 99.71%Cor e Forma:SolidPeso molecular:2126.47MSX-130
CAS:<p>MSX-130 is CXCR4 Antagonist.</p>Fórmula:C36H26N4Pureza:99.19%Cor e Forma:SolidPeso molecular:514.62GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Cor e Forma:SolidPeso molecular:489.91Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Fórmula:C16H14F3IN2O4Pureza:99.11% - 99.63%Cor e Forma:White PowderPeso molecular:482.19GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Fórmula:C28H22Cl3NO4Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:542.84SRT3109
CAS:<p>SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.</p>Fórmula:C18H23F2N5O4S2Pureza:99.65% - 99.92%Cor e Forma:SolidPeso molecular:475.53Pyriproxyfen
CAS:<p>Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.</p>Fórmula:C20H19NO3Pureza:99.83%Cor e Forma:Solid CompactPeso molecular:321.37Plerixafor
CAS:<p>Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.</p>Fórmula:C28H54N8Pureza:99.17% - >99.99%Cor e Forma:SolidPeso molecular:502.78AZD-5069
CAS:<p>AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).</p>Fórmula:C18H22F2N4O5S2Pureza:98.38% - 98.63%Cor e Forma:SolidPeso molecular:476.52Plerixafor octahydrochloride
CAS:<p>Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.</p>Fórmula:C28H62Cl8N8Pureza:98.01% - 99.79%Cor e Forma:SolidPeso molecular:794.46SX-682
CAS:<p>SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.</p>Fórmula:C19H14BF4N3O4SPureza:98.19% - 99.57%Cor e Forma:SolidPeso molecular:467.2ZSTK474
CAS:<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Fórmula:C19H21F2N7O2Pureza:98.29% - 99.95%Cor e Forma:White PowderPeso molecular:417.41BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Fórmula:C23H26IN7O2SPureza:98% - 99.57%Cor e Forma:SolidPeso molecular:591.47Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Fórmula:C20H20O4Pureza:98% - 99.76%Cor e Forma:SolidPeso molecular:324.37Oxyresveratrol
CAS:<p>1.</p>Fórmula:C14H12O4Pureza:98.09% - 99.69%Cor e Forma:Yellow SolidPeso molecular:244.24HG-10-102-01
CAS:<p>HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).</p>Fórmula:C17H20ClN5O3Pureza:99.59%Cor e Forma:SolidPeso molecular:377.83NVP-AEW541
CAS:<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Fórmula:C27H29N5OPureza:98.7% - 99.86%Cor e Forma:SolidPeso molecular:439.55Lucanthone
CAS:<p>Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).</p>Fórmula:C20H24N2OSPureza:99.92%Cor e Forma:Yellow Crystals From Alcohol SolidPeso molecular:340.48Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Fórmula:C32H29N5O2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:515.6MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Fórmula:C25H34N6O·HClPureza:99.86% - 99.98%Cor e Forma:SolidPeso molecular:471.04Schisandrin
CAS:<p>Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.</p>Fórmula:C24H32O7Pureza:98.97% - 99.32%Cor e Forma:White PowderPeso molecular:432.51Pennogenin 3-O-β-chacotrioside
CAS:<p>Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.</p>Fórmula:C45H72O17Pureza:99.69% - 99.77%Cor e Forma:SolidPeso molecular:885.04RITA
CAS:<p>RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.</p>Fórmula:C14H12O3S2Pureza:98.49% - 99.55%Cor e Forma:SolidPeso molecular:292.374EGI-1
CAS:<p>4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).</p>Fórmula:C18H12Cl2N4O4SPureza:96.8% - 99.12%Cor e Forma:SolidPeso molecular:451.28Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Cor e Forma:Yellow SolidPeso molecular:384.24CZC-25146 hydrochloride
CAS:<p>CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.</p>Fórmula:C22H26ClFN6O4SPureza:98.76%Cor e Forma:SolidPeso molecular:525Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Fórmula:C9H10O5Pureza:98.4% - 99.74%Cor e Forma:SolidPeso molecular:198.17SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Fórmula:C22H27ClN2O3Pureza:99.47% - 99.92%Cor e Forma:SolidPeso molecular:402.91Vitexin
CAS:<p>Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.</p>Fórmula:C21H20O10Pureza:98.13% - 99.64%Cor e Forma:Yellow PowderPeso molecular:432.3810074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Fórmula:C18H12N4O3Pureza:99.51% - 99.67%Cor e Forma:SolidPeso molecular:332.31KN-93
CAS:<p>KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.</p>Fórmula:C26H29ClN2O4SPureza:99.56% - 99.86%Cor e Forma:White SolidPeso molecular:501.04Taxifolin
CAS:<p>Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.</p>Fórmula:C15H12O7Pureza:94.91% - 98.9%Cor e Forma:Yellowish PowderPeso molecular:304.25Vinorelbine ditartrate
CAS:<p>Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.</p>Fórmula:C45H54N4O8·2C4H6O6Pureza:98% - 99.86%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:1079.11UNBS5162
CAS:<p>UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.</p>Fórmula:C17H18N4O3Pureza:98.37% - 99.97%Cor e Forma:SolidPeso molecular:326.35RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Fórmula:C24H16F6N6OPureza:99.56%Cor e Forma:SolidPeso molecular:518.41D-glutamine
CAS:<p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>Fórmula:C5H10N2O3Pureza:99.99%Cor e Forma:White Or Off-White PowderPeso molecular:146.14IU1
CAS:<p>IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。</p>Fórmula:C18H21FN2OPureza:98% - 99.3%Cor e Forma:SolidPeso molecular:300.37BGT226
CAS:<p>BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.</p>Fórmula:C28H25F3N6O2Pureza:95.74% - 99.51%Cor e Forma:SolidPeso molecular:534.53PF-3845
CAS:<p>PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.</p>Fórmula:C24H23F3N4O2Pureza:99.54% - 99.58%Cor e Forma:SolidPeso molecular:456.46Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25ML-SA1
CAS:<p>ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.</p>Fórmula:C22H22N2O3Pureza:99.34% - 99.71%Cor e Forma:SolidPeso molecular:362.42Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Fórmula:C23H28N8OSPureza:99.99%Cor e Forma:SolidPeso molecular:464.59Zoledronic Acid
CAS:<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Fórmula:C5H10N2O7P2Pureza:98% - 99.93%Cor e Forma:White Crystalline PowderPeso molecular:272.09Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Cor e Forma:SolidPeso molecular:322.31QX77
CAS:<p>QX77 is a chaperone-mediated autophagy (CMA) activator.</p>Fórmula:C16H13ClN2O2Pureza:98.21%Cor e Forma:SolidPeso molecular:300.74NH125
CAS:<p>NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.</p>Fórmula:C27H45IN2Pureza:98.60%Cor e Forma:SolidPeso molecular:524.56Sertindole
CAS:<p>Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).</p>Fórmula:C24H26ClFN4OPureza:99.87% - 99.92%Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:440.94Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Fórmula:C31H43N3O8Pureza:99.07% - 99.83%Cor e Forma:Dark Purple SolidPeso molecular:585.69STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Fórmula:C19H10N2O3Pureza:97.14% - 98.8%Cor e Forma:SolidPeso molecular:314.29CX546
CAS:<p>CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.</p>Fórmula:C14H17NO3Pureza:99.75%Cor e Forma:SolidPeso molecular:247.29Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Cor e Forma:SolidPeso molecular:450.51Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Fórmula:C29H32N6O4SPureza:98% - 99.42%Cor e Forma:SolidPeso molecular:560.675-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Fórmula:C5H10ClNO3Pureza:98% - 99.97%Cor e Forma:White To Pale Yellow Crystals OrPeso molecular:167.59Ulipristal acetate
CAS:<p>Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.</p>Fórmula:C30H37NO4Pureza:98.83% - 99.94%Cor e Forma:SolidPeso molecular:475.62Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.91Nidufexor
CAS:<p>Nidufexor is an agonist for the farnesoid X receptor (FXR).</p>Fórmula:C27H22ClN3O4Pureza:98.67%Cor e Forma:SolidPeso molecular:487.93Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Cor e Forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14UNC0638
CAS:<p>UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.</p>Fórmula:C30H47N5O2Pureza:98.88% - 99.53%Cor e Forma:SolidPeso molecular:509.73CA-5f
CAS:<p>CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.</p>Fórmula:C24H24N2O3Pureza:99.69%Cor e Forma:SolidPeso molecular:388.46Ginkgetin
CAS:<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Fórmula:C32H22O10Pureza:98.63% - 99.94%Cor e Forma:SolidPeso molecular:566.51Rilmenidine Phosphate
CAS:<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Fórmula:C10H19N2O5PPureza:99.87% - ≥95%Cor e Forma:SolidPeso molecular:278.24PF-06447475
CAS:<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Fórmula:C17H15N5OPureza:98.61% - 99.62%Cor e Forma:SolidPeso molecular:305.33Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Cor e Forma:SolidPeso molecular:516.65Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Fórmula:C4H11N5Pureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:129.16Indomethacin farnesil
CAS:<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Fórmula:C34H40ClNO4Pureza:97.29%Cor e Forma:SolidPeso molecular:562.14SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Cor e Forma:Pale YellowPeso molecular:331.34CaMKII-IN-1
CAS:<p>CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).</p>Fórmula:C29H30ClN5O2SPureza:99.69%Cor e Forma:SolidPeso molecular:548.1Dihydromyricetin
CAS:<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Fórmula:C15H12O8Pureza:96.68% - 98.229%Cor e Forma:SolidPeso molecular:320.25MHY1485
CAS:<p>MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.</p>Fórmula:C17H21N7O4Pureza:97.74% - >99.99%Cor e Forma:SolidPeso molecular:387.39(-)-Epicatechin gallate
CAS:<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Fórmula:C22H18O10Pureza:99.16% - 99.93%Cor e Forma:SolidPeso molecular:442.371-Monomyristin
CAS:<p>1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial</p>Fórmula:C17H34O4Pureza:99.58%Cor e Forma:SolidPeso molecular:302.45Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Fórmula:C33H40O15Pureza:97.82% - 98.3%Cor e Forma:SolidPeso molecular:676.66Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Fórmula:C14H11N3O3SPureza:98% - 99.91%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:301.32CFTR(inh)-172
CAS:<p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>Fórmula:C18H10F3NO3S2Pureza:98% - 99.72%Cor e Forma:SolidPeso molecular:409.4ULK-101
CAS:<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Fórmula:C22H16F4N4OSPureza:97.55% - 99.94%Cor e Forma:SolidPeso molecular:460.45Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Cor e Forma:SolidPeso molecular:500.78Syringin
CAS:<p>Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.</p>Fórmula:C17H24O9Pureza:98.89% - 99.56%Cor e Forma:SolidPeso molecular:372.37PATULIN
CAS:<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Fórmula:C7H6O4Pureza:99.91% - 99.98%Cor e Forma:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallinePeso molecular:154.12Purmorphamine
CAS:<p>Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.</p>Fórmula:C31H32N6O2Pureza:97.19% - 99.48%Cor e Forma:Light Tan SolidPeso molecular:520.62Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:500.83Genipin
CAS:<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Fórmula:C11H14O5Pureza:99.09% - 99.21%Cor e Forma:SolidPeso molecular:226.23VER-155008
CAS:<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Fórmula:C25H23Cl2N7O4Pureza:97.03% - 99.55%Cor e Forma:SolidPeso molecular:556.4Pitavastatin calcium
CAS:<p>Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.</p>Fórmula:C50H46CaF2N2O8Pureza:98.89% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:880.98Tarenflurbil
CAS:<p>Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.</p>Fórmula:C15H13FO2Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:244.26Efavirenz
CAS:<p>Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.</p>Fórmula:C14H9ClF3NO2Pureza:99.2% - 99.84%Cor e Forma:White To Slightly Pink Crystalline PowderPeso molecular:315.67D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Fórmula:C23H18N4O3Pureza:99.7% - 99.96%Cor e Forma:SolidPeso molecular:398.41Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Fórmula:C30H23N5OPureza:97.64% - 99.85%Cor e Forma:SolidPeso molecular:469.54Skatole
CAS:<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Fórmula:C9H9NPureza:99.74%Cor e Forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17MW-150
CAS:<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Fórmula:C24H23N5Pureza:97.35% - 99.27%Cor e Forma:SolidPeso molecular:381.47Lumefantrine
CAS:<p>Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.</p>Fórmula:C30H32Cl3NOPureza:98.36%Cor e Forma:Yellow SolidPeso molecular:528.94Shogaol
CAS:<p>6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.</p>Fórmula:C17H24O3Pureza:98.26% - 99.93%Cor e Forma:SolidPeso molecular:276.37Dapivirine
CAS:<p>Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H19N5Pureza:98% - 99.77%Cor e Forma:SolidPeso molecular:329.4PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Cor e Forma:SolidPeso molecular:348.36Tezacaftor
CAS:<p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>Fórmula:C26H27F3N2O6Pureza:98.84% - >99.99%Cor e Forma:SolidPeso molecular:520.5NS1643
CAS:<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Fórmula:C15H10F6N2O3Pureza:98.37% - 99.31%Cor e Forma:SolidPeso molecular:380.24Irinotecan
CAS:<p>Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.</p>Fórmula:C33H38N4O6Pureza:98% - 99.92%Cor e Forma:SolidPeso molecular:586.68LY2109761
CAS:<p>LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.</p>Fórmula:C26H27N5O2Pureza:97% - 99.83%Cor e Forma:SolidPeso molecular:441.52trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Fórmula:C29H33NO4Pureza:99.51%Cor e Forma:SolidPeso molecular:459.58Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Fórmula:C13H16N2O2Pureza:98% - 99.89%Cor e Forma:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Fórmula:C19H18O9Pureza:99.64% - 99.85%Cor e Forma:SolidPeso molecular:390.34Peiminine
CAS:<p>1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.</p>Fórmula:C27H43NO3Pureza:99.52% - ≥95%Cor e Forma:White PowderPeso molecular:429.64Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Fórmula:C53H84NO14PPureza:90.00% - 98.55%Cor e Forma:Off-White SolidPeso molecular:990.21Oroxylin A
CAS:<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Fórmula:C16H12O5Pureza:98.72% - 99.55%Cor e Forma:SolidPeso molecular:284.26SBI-0640756
CAS:<p>SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.</p>Fórmula:C23H14ClFN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:404.82Enzalutamide
CAS:<p>Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).</p>Fórmula:C21H16F4N4O2SPureza:99% - 99.93%Cor e Forma:SolidPeso molecular:464.44Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Fórmula:C21H24O6Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:372.41PRIMA-1
CAS:<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Fórmula:C9H15NO3Pureza:99.22%Cor e Forma:SolidPeso molecular:185.22Fexaramine
CAS:<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Fórmula:C32H36N2O3Pureza:98.87% - 99.61%Cor e Forma:SolidPeso molecular:496.64GSK2656157
CAS:<p>GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.</p>Fórmula:C23H21FN6OPureza:98.59% - >99.99%Cor e Forma:SolidPeso molecular:416.45PD-166866
CAS:<p>PD-166866 is a selective FGFR tyrosine kinase inhibitor.</p>Fórmula:C20H24N6O3Pureza:98.29%Cor e Forma:SolidPeso molecular:396.44ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Fórmula:C12H22ClN3OSPureza:99.3%Cor e Forma:SolidPeso molecular:291.84Pictilisib
CAS:<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Fórmula:C23H27N7O3S2Pureza:98.69% - 99.97%Cor e Forma:SolidPeso molecular:513.64Sedanolide
CAS:<p>Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.</p>Fórmula:C12H18O2Pureza:≥95% - ≥98%Cor e Forma:SolidPeso molecular:194.27(-)-Epigallocatechin
CAS:<p>(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their</p>Fórmula:C15H14O7Pureza:98.83% - >99.99%Cor e Forma:White PowderPeso molecular:306.27SF1670
CAS:<p>SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.</p>Fórmula:C19H17NO3Pureza:98.25% - 98.54%Cor e Forma:SolidPeso molecular:307.34Thiamet G
CAS:<p>Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!</p>Fórmula:C9H16N2O4SPureza:99.06% - 99.98%Cor e Forma:SolidPeso molecular:248.3Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Fórmula:C22H34O7Pureza:98.83% - 99.96%Cor e Forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecular:410.56-Thioguanine
CAS:<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Fórmula:C5H5N5SPureza:98.34% - >99.99%Cor e Forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19Calcineurin substrate acetate
<p>Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.</p>Fórmula:C94H154N28O31Pureza:97.59%Cor e Forma:SolidPeso molecular:2172.4Cinobufagin
CAS:<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Fórmula:C26H34O6Pureza:97.77% - 99.97%Cor e Forma:SolidPeso molecular:442.54BIX-01294
CAS:<p>BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).</p>Fórmula:C28H38N6O2Pureza:98.58% - 99.64%Cor e Forma:SolidPeso molecular:490.64PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Fórmula:C24H25ClN6OPureza:99.13%Cor e Forma:SolidPeso molecular:448.95Schisandrin B
CAS:<p>Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.</p>Fórmula:C23H28O6Pureza:99.02% - >99.99%Cor e Forma:SolidPeso molecular:400.46(R)-(-)-Gossypol acetic acid
CAS:<p>(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.</p>Fórmula:C30H30O8·C2H4O2Pureza:98.88% - 99.5%Cor e Forma:SolidPeso molecular:578.61Dantrolene sodium hemiheptahydrate
CAS:<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Fórmula:C14H9N4NaO5·5H2OPureza:99.72%Cor e Forma:Orange PowderPeso molecular:399.29Tripterin
CAS:<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Fórmula:C29H38O4Pureza:98.56% - 99.8%Cor e Forma:Red Crystalline PowderPeso molecular:450.61Mito-LND
CAS:<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Fórmula:C43H45BrCl2N3OPPureza:97.25% - 98.34%Cor e Forma:SolidPeso molecular:801.62mTOR inhibitor-1
CAS:<p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>Fórmula:C16H15BrN2O3Pureza:99.43%Cor e Forma:SolidPeso molecular:363.21AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:381.43Osu03012
CAS:<p>Osu03012 (AR-12): oral celecoxib-derived PDK1 inhibitor with anticancer potential.</p>Fórmula:C26H19F3N4OPureza:97.95% - 99.22%Cor e Forma:SolidPeso molecular:460.45Afzelin
CAS:<p>Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-</p>Fórmula:C21H20O10Pureza:98.92% - 99.38%Cor e Forma:SolidPeso molecular:432.38Icaritin
CAS:<p>Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.</p>Fórmula:C21H20O6Pureza:97.69% - 99.76%Cor e Forma:SolidPeso molecular:368.38Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61LY3009120
CAS:<p>LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.</p>Fórmula:C23H29FN6OPureza:96.96% - ≥95%Cor e Forma:SolidPeso molecular:424.51Divalproex Sodium
CAS:<p>Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by</p>Fórmula:C8H16O2·C8H15O2·NaPureza:99.87%Cor e Forma:A White Powder With A Characteristic OdorPeso molecular:310.41Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.66Fludrocortisone acetate
CAS:<p>Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and</p>Fórmula:C23H31FO6Pureza:96.92% - 98.03%Cor e Forma:Crystalline SolidPeso molecular:422.49Tamibarotene
CAS:<p>Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic</p>Fórmula:C22H25NO3Pureza:98.55% - 99.73%Cor e Forma:Crystalline SolidPeso molecular:351.44Vinblastine sulfate
CAS:<p>Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).</p>Fórmula:C46H58N4O9·H2SO4Pureza:97.81% - 99.68%Cor e Forma:White PowderPeso molecular:909.06WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Fórmula:C24H29N7O5Pureza:97.86% - 99.61%Cor e Forma:SolidPeso molecular:495.53Tacrolimus
CAS:<p>Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein</p>Fórmula:C44H69NO12Pureza:98% - 99.94%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:804.02(E)-Daporinad
CAS:<p>(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT） .Cost-effective and quality-assured.</p>Fórmula:C24H29N3O2Pureza:98.44% - >99.99%Cor e Forma:SolidPeso molecular:391.51Licochalcone A
CAS:<p>Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.</p>Fórmula:C21H22O4Pureza:98.17% - 99.60%Cor e Forma:White Crystalline PowderPeso molecular:338.4Corosolic acid
CAS:<p>Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.</p>Fórmula:C30H48O4Pureza:99.46% - 99.88%Cor e Forma:Fine-Brown Yellow PowderPeso molecular:472.7N-Benzylpalmitamide
CAS:<p>N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the</p>Fórmula:C23H39NOPureza:97.08% - 99.77%Cor e Forma:SolidPeso molecular:345.56Parthenolide
CAS:<p>Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.</p>Fórmula:C15H20O3Pureza:98.19% - 99.46%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:248.328-Chloroadenosine
CAS:<p>8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.</p>Fórmula:C10H12ClN5O4Pureza:98.75% - 99.84%Cor e Forma:SolidPeso molecular:301.69Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Fórmula:C21H25ClN6O2Pureza:97.59% - 99.6%Cor e Forma:SolidPeso molecular:428.92Dorsomorphin dihydrochloride
CAS:<p>Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on</p>Fórmula:C24H25N5O·2HClPureza:97.74% - 99.89%Cor e Forma:SolidPeso molecular:472.413PO
CAS:<p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>Fórmula:C13H10N2OPureza:99.56% - 99.67%Cor e Forma:SolidPeso molecular:210.23Glycycoumarin
CAS:<p>Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.</p>Fórmula:C21H20O6Pureza:97.64% - 99.78%Cor e Forma:SolidPeso molecular:368.38PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Cor e Forma:SolidPeso molecular:369.22Vemurafenib
CAS:<p>Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.</p>Fórmula:C23H18ClF2N3O3SPureza:98% - 99.65%Cor e Forma:SolidPeso molecular:489.92Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Cor e Forma:Off-White To Light Yellow PowdPeso molecular:958.22Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H31N3O5Pureza:98% - 99.25%Cor e Forma:SolidPeso molecular:465.54Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Cor e Forma:SolidPeso molecular:246.35Dinoprost tromethamine salt
CAS:<p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>Fórmula:C24H45NO8Pureza:99.73%Cor e Forma:Natural Form Crystals SolidPeso molecular:475.62Idarubicin
CAS:<p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>Fórmula:C26H27NO9Cor e Forma:SolidPeso molecular:497.49
