GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

Exibir 18 mais subcategorias

Foram encontrados 5378 produtos de "GPCR/Proteína-G"

Pureza (%)

100

produtos por página.

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KSK94 FA
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.
Fórmula:C₂₆H₂₈N₄O₃
Pureza:97.51%
Cor e Forma:Soild
Peso molecular:444.53
Ref: TM-T79500L
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Relaxin H3 (human)
CAS:
- 1158181-62-4
Relaxin H3 (human) is a relaxin peptide that exhibits antifibrotic effects through activation of RXFP1 [1].
Cor e Forma:Solid
Ref: TM-T81300
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CB2R agonist 2
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].
Pureza:98%
Cor e Forma:Odour Solid
Ref: TM-T82770
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Uroguanylin (human)
CAS:
- 154525-25-4
Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effects
Fórmula:C₆₄H₁₀₂N₁₈O₂₆S₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:1667.86
Ref: TM-T80067
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N,N′-Diferuloylputrescine
CAS:
- 42369-86-8
N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation.
Fórmula:C₂₄H₂₈N₂O₆
Pureza:98%
Cor e Forma:Solid
Peso molecular:440.49
Ref: TM-T79996
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CAY10580
CAS:
- 64054-40-6
CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).
Fórmula:C₁₉H₃₅NO₄
Cor e Forma:Solid
Peso molecular:341.49
Ref: TM-T40738
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PACAP-38 (31-38), human, mouse, rat acetate
PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.
Fórmula:C₄₉H₈₇N₁₇O₁₃
Pureza:99.92%
Cor e Forma:Solid
Peso molecular:1122.32
Ref: TM-TP1618L
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SLB1122168 formic
SLB1122168 is a potent inhibitor of Spns2-mediated sphingosine-1-phosphate (S1P) release, exhibiting an IC50 value of 94 nM [1].
Fórmula:C₂₃H₃₇N₃O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:403.56
Ref: TM-T78160
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12-epi Leukotriene B4
CAS:
- 83709-73-3
LTB4 is made enzymatically (12(R)-specific) and non-enzymatically (6-trans-12-epi mix). 12-epi LTB4 has low receptor activity.
Fórmula:C₂₀H₃₂O₄
Cor e Forma:Solid
Peso molecular:336.472
Ref: TM-T37970
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Dapoxetine
CAS:
- 119356-77-3
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
Fórmula:C₂₁H₂₃NO
Pureza:99.73%
Cor e Forma:White To Off-White Crystalline Powder
Peso molecular:305.42
Ref: TM-T0039
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Dolcanatide
CAS:
- 1092457-65-2
Dolcanatide: oral GC-C agonist with laxative, pain-relief, and anti-inflammatory properties for IBD research.
Fórmula:C₆₅H₁₀₄N₁₈O₂₆S₄
Cor e Forma:Solid
Peso molecular:1681.89
Ref: TM-T76274
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Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].
Fórmula:C₁₉₃H₃₃₁F₃N₆₄O₅₅S₃
Cor e Forma:Solid
Peso molecular:4581.28
Ref: TM-T75873
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[Ala1,3,11,15]-Endothelin
CAS:
- 121204-87-3
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
Fórmula:C₁₀₉H₁₆₃N₂₅O₃₂S
Pureza:98%
Cor e Forma:Solid
Peso molecular:2368
Ref: TM-TP2099
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CB2R probe 1
CAS:
- 2634714-79-5
CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of
Fórmula:C₃₆H₄₂N₄O₄
Cor e Forma:Solid
Peso molecular:594.74
Ref: TM-T74604
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17-phenyl trinor Prostaglandin F2α cyclopropyl amide
CAS:
- 1138395-12-6
17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide.
Fórmula:C₂₆H₃₇NO₄
Cor e Forma:Solid
Peso molecular:427.585
Ref: TM-T37940
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Sufotidine
CAS:
- 80343-63-1
Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.
Fórmula:C₂₀H₃₁N₅O₃S
Pureza:99.03% - 99.92%
Cor e Forma:Solid
Peso molecular:421.56
Ref: TM-T68146
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L-797,591 hydrochloride
L-797,591 HCl activates SSTR1, boosts p-ERK5 with AG1478, and enhances p38 phosphorylation, reversible by AG1478.
Fórmula:C₃₈H₅₀ClN₅O₂
Pureza:98.65% - >99.99%
Cor e Forma:Soild
Peso molecular:644.30
Ref: TM-T27787L
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CCR8 antagonist 1
CAS:
- 723304-76-5
CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.
Fórmula:C₂₆H₂₉N₃O₅S
Pureza:99.51%
Cor e Forma:Solid
Peso molecular:495.59
Ref: TM-T9983
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YFLLRNP
CAS:
- 149440-16-4
YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.
Fórmula:C₄₅H₆₇N₁₁O₁₀
Cor e Forma:Solid
Peso molecular:922.08
Ref: TM-T80235
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Alosetron-d3
CAS:
- 1190043-13-0
Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.
Fórmula:C₁₇H₁₈N₄O
Pureza:98%
Cor e Forma:Solid
Peso molecular:297.37
Ref: TM-T19191