GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(940 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.943 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(196 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(69 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(164 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5338 produtos de "GPCR/Proteína-G"
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Amiselimod hydrochloride
CAS:<p>Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.</p>Fórmula:C19H31ClF3NO3Pureza:99.55%Cor e Forma:SolidPeso molecular:413.9Acetophenazine dimaleate
CAS:<p>Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.</p>Fórmula:C31H37N3O10SPureza:99.39% - 99.48%Cor e Forma:SolidPeso molecular:643.71Cetirizine dihydrochloride
CAS:Cetirizine dihydrochloride is a potent non-drowsy antihistamine for allergies and asthma.Fórmula:C21H27Cl3N2O3Pureza:99.4% - 99.97%Cor e Forma:SolidPeso molecular:461.81CP-809101 hydrochloride
CAS:<p>CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).</p>Fórmula:C15H18Cl2N4OPureza:99.5%Cor e Forma:SolidPeso molecular:341.24Alfuzosin hydrochloride
CAS:<p>Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).</p>Fórmula:C19H27N5O4·HClPureza:99.78%Cor e Forma:White To Off-White SolidPeso molecular:425.91Urapidil hydrochloride
CAS:<p>Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.</p>Fórmula:C20H29N5O3·HClPureza:99.58%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:423.94KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Fórmula:C26H40N4O8Pureza:98.46%Cor e Forma:SolidPeso molecular:536.62Promazine hydrochloride
CAS:<p>Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.</p>Fórmula:C17H21ClN2SPureza:99.90%Cor e Forma:SolidPeso molecular:320.88Urocortin (rat) acetate
<p>Urocortin (rat) acetate: CRF receptor agonist; Ki=13nM (hCRF1), 1.5nM (rCRF2α), 0.97nM (mCRF2β); neuropeptide.</p>Pureza:97.76%Cor e Forma:SoildChlorprothixene hydrochloride
CAS:<p>Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.</p>Fórmula:C18H18ClNS·HClPureza:99.76%Cor e Forma:White PowderPeso molecular:352.32CYM 50769
CAS:<p>CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).</p>Fórmula:C24H17ClN2O3Pureza:98% - 99.08%Cor e Forma:SolidPeso molecular:416.86hGPR91 antagonist 1
CAS:<p>hGPR91 antagonist 1 is a potent and selective hGPR91 antagonist (IC50: 7 μM).</p>Fórmula:C31H23F4N3OPureza:98.89%Cor e Forma:SolidPeso molecular:529.53PF429242 dihydrochloride
CAS:<p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>Fórmula:C25H37Cl2N3O2Pureza:99.68%Cor e Forma:SolidPeso molecular:482.49Prucalopride
CAS:<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.</p>Fórmula:C18H26ClN3O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:367.87Fluvoxamine maleate
CAS:<p>Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety</p>Fórmula:C19H25F3N2O6Pureza:99.92% - 99.94%Cor e Forma:White Crystalline PowderPeso molecular:434.41Cyproheptadine hydrochloride sesquihydrate
CAS:<p>Cyproheptadine hydrochloride sesquihydrate (Peritol), an antihistamine, is an antagonist of serotonin and histamine2.</p>Fórmula:C21H24ClNOPureza:99.77% - >99.99%Cor e Forma:White To Slightly Yellowish Crystalline SolidPeso molecular:341.88Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Fórmula:C16H21N3O2Pureza:99.69% - 99.91%Cor e Forma:White Or Kind Of White PowderPeso molecular:287.36Ziprasidone hydrochloride
CAS:<p>Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic</p>Fórmula:C21H22CL2N4OSPureza:97.97% - 99.82%Cor e Forma:SolidPeso molecular:449.4Olinciguat
CAS:<p>Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.</p>Fórmula:C21H16F5N7O3Pureza:99.33% - 99.71%Cor e Forma:SolidPeso molecular:509.39YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Fórmula:C33H37N5O5SPureza:99.67%Cor e Forma:SolidPeso molecular:615.74Dopexamine hydrochloride
CAS:<p>Dopexamine hydrochloride (FPL60278AR) is a β2-adrenoceptor agonist that modulates inflammation and protects organs without affecting hemodynamics.</p>Fórmula:C22H34Cl2N2O2Pureza:98.55%Cor e Forma:SolidPeso molecular:429.42Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Cor e Forma:SolidPeso molecular:395.43Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Fórmula:C26H35NO7Pureza:98.53% - 99.43%Cor e Forma:CoaPeso molecular:473.57Ondansetron hydrochloride dihydrate
CAS:<p>Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.</p>Fórmula:C18H19N3O·HCl·2H2OPureza:99.92%Cor e Forma:White Crystal PowderPeso molecular:365.86Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Fórmula:C19H21NSPureza:99.93%Cor e Forma:SolidPeso molecular:295.44ML-180
CAS:<p>ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .</p>Fórmula:C20H25ClN4O2Pureza:99.74%Cor e Forma:SolidPeso molecular:388.89Nylidrin hydrochloride
CAS:<p>Nylidrin HCl inhibits IgG1-induced histamine release in guinea pigs and IgE-induced release in rat mast cells & human basophils.</p>Fórmula:C19H26ClNO2Pureza:99.35%Cor e Forma:SolidPeso molecular:335.87JNJ-18038683
CAS:<p>JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.</p>Fórmula:C26H28ClN3O7Pureza:97.29%Cor e Forma:SolidPeso molecular:529.97Talastine
CAS:<p>Talastine is an antihistamine compound that can induce an allergic rash.</p>Fórmula:C19H21N3OPureza:98.50% - 99.44%Cor e Forma:SolidPeso molecular:307.39Lafutidine
CAS:<p>Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.</p>Fórmula:C22H29N3O4SPureza:98.55%Cor e Forma:Yellowish White Crystalline PowderPeso molecular:431.55Clonidine hydrochloride
CAS:<p>Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.</p>Fórmula:C9H10Cl3N3Pureza:99.16% - 99.86%Cor e Forma:SolidPeso molecular:266.55Rimonabant
CAS:<p>Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.</p>Fórmula:C22H21Cl3N4OPureza:98% - 99.91%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:463.79Silodosin
CAS:<p>Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.</p>Fórmula:C25H32F3N3O4Pureza:99.282% - 99.76%Cor e Forma:Colorless To Pink SolidPeso molecular:495.53Metaproterenol hemisulfate
CAS:<p>Metaproterenol hemisulfate (Orciprenaline sulfate) is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.</p>Fórmula:C11H17NO3·5H2O4SPureza:98.53% - 99.74%Cor e Forma:SolidPeso molecular:260.3Fluparoxan hydrochloride
CAS:<p>Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Fórmula:C10H11ClFNO2Pureza:99.98%Cor e Forma:SoildPeso molecular:231.65Levosulpiride
CAS:<p>Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.</p>Fórmula:C15H23N3O4SPureza:98.20% - 99.88%Cor e Forma:White Crystalline PowderPeso molecular:341.43Venlafaxine hydrochloride
CAS:<p>Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.</p>Fórmula:C17H28ClNO2Pureza:97.32% - 99.86%Cor e Forma:White Crystalline PowderPeso molecular:313.86Noradrenaline bitartrate
CAS:<p>Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors.</p>Fórmula:C12H19NO10Pureza:99.53% - >99.99%Cor e Forma:SolidPeso molecular:337.28Aripiprazole
CAS:<p>Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.</p>Fórmula:C23H27Cl2N3O2Pureza:99.43% - 99.62%Cor e Forma:Colourless Flake Crystalline SolidPeso molecular:448.39(3aR,9aR)-Fluparoxan
CAS:<p>(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Fórmula:C10H10FNO2Pureza:97.82%Cor e Forma:SoildPeso molecular:195.19AH 6809
CAS:<p>AH 6809 blocks EP1, EP2, EP3, DP receptors (Ki: 1217-1597 nM human, 350 nM mouse EP2).</p>Fórmula:C17H14O5Pureza:97.59%Cor e Forma:SolidPeso molecular:298.29Phenothiazine
CAS:<p>Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.</p>Fórmula:C12H9NSPureza:99.95%Cor e Forma:Yellow Solid PelletsPeso molecular:199.27(R)-Elagolix
CAS:<p>(R)-Elagolix (NBI-56418) is an orally active, highly selective, short-term potent antagonist of the non-peptide gonadotropin-releasing hormone receptor.</p>Fórmula:C32H30F5N3O5Pureza:99.08%Cor e Forma:SolidPeso molecular:631.59Indacaterol maleate
CAS:<p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>Fórmula:C28H32N2O7Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:508.56Moxisylyte hydrochloride
CAS:<p>Moxisylyte hydrochloride (Thymoxamine hydrochloride) is an alpha-adrenergic blocking agent that is used in Raynaud's disease.</p>Fórmula:C16H26ClNO3Pureza:99.93% - ≥95%Cor e Forma:SolidPeso molecular:315.842-Bromo-6-methoxynaphthalene
CAS:<p>2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.</p>Fórmula:C11H9BrOPureza:98.51%Cor e Forma:White To Off-White PowderPeso molecular:237.09Roxatidine Acetate hydrochloride
CAS:<p>Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. Roxatidine inhibits gastric acid secretion.</p>Fórmula:C19H29ClN2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:384.9Methyldopa
CAS:<p>Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or</p>Fórmula:C10H13NO4Pureza:98.95% - 99.86%Cor e Forma:Less Or Almost Colorless Crystals Or White To Yellowish-White FinePeso molecular:211.21Filorexant
CAS:<p>Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).</p>Fórmula:C24H25FN4O2Pureza:98.88%Cor e Forma:SolidPeso molecular:420.48Granisetron hydrochloride
CAS:<p>Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy</p>Fórmula:C18H25ClN4OPureza:99.88% - 99.93%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:348.87
