GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(939 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.945 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(358 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5352 produtos de "GPCR/Proteína-G"
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Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:<p>CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.</p>Fórmula:C163H267N51O50S2Pureza:98%Cor e Forma:SolidPeso molecular:3805.3117-phenyl trinor Prostaglandin E2 ethyl amide
CAS:<p>17-phenyl trinor PGE2 ethyl amide, an EP1/EP3 agonist (Ki: 14-54 nM), enhances lipid solubility and tissue uptake, is a potent antifertility agent.</p>Fórmula:C25H35NO4Cor e Forma:SolidPeso molecular:413.55HAEGTFTSDVS
CAS:<p>HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.</p>Fórmula:C48H71N13O20Pureza:98%Cor e Forma:SolidPeso molecular:1150.18Leukotriene B5
CAS:<p>LTB5, an eicosapentaenoic acid metabolite via 5-LO, has varied bioactivities and enhances bullfrog lung strip contraction.</p>Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.456IRL-1620
CAS:<p>IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).</p>Fórmula:C86H117N17O27Pureza:98%Cor e Forma:SolidPeso molecular:1820.97417-phenoxy trinor Prostaglandin F2α ethyl amide
CAS:<p>Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.</p>Fórmula:C25H37NO5Cor e Forma:SolidPeso molecular:431.573Ethylpropyltryptamine
CAS:<p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.35S(-)-Bisoprolol fumarate
CAS:<p>S(-)-Bisoprolol fumarate is a selective β1-blocker for hypertension and heart research.</p>Fórmula:C18H31NO4·xC4H4O4Cor e Forma:SolidPeso molecular:441.521M1145
CAS:<p>Potent GAL2 agonist with EC50 = 38 nM; Ki: 6.55 nM (GAL2), 497 nM (GAL3), 587 nM (GAL1); enhances galanin signaling.</p>Fórmula:C128H205N37O32Pureza:98%Cor e Forma:SolidPeso molecular:2774.261-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
CAS:<p>1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.</p>Fórmula:C15H11FN2O2Cor e Forma:SolidPeso molecular:270.265-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Pureza:99.77%Cor e Forma:Odour SolidMini Gastrin I, human
CAS:<p>Mini Gastrin I, human, is a truncated form of the human gastrin peptide, encompassing amino acids 5-17 of the original sequence.</p>Fórmula:C74H99N15O26SPureza:98%Cor e Forma:SolidPeso molecular:1646.73LGnRH-III, lamprey
CAS:<p>GnRH III triggers luteinizing and follicle-stimulating hormone release, part of the conserved GnRH family.</p>Fórmula:C59H74N18O14Pureza:98%Cor e Forma:SolidPeso molecular:1259.33Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Fórmula:C154H244N47F3O46S4Pureza:98%Cor e Forma:SolidPeso molecular:3675.12Gemeprost
CAS:<p>Gemeprost treats obstetric bleeding and induces abortion up to 24 weeks when used with mifepristone.</p>Fórmula:C23H38O5Pureza:98%Cor e Forma:SolidPeso molecular:394.54Neuropeptide Y (human)
CAS:<p>Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.</p>Fórmula:C189H285N55O57SPureza:98%Cor e Forma:SolidPeso molecular:4271.68Neurokinin B
CAS:<p>NKB, a tachykinin peptide, impacts human functions like gonadotropin-releasing hormone secretion.</p>Fórmula:C55H79N13O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1210.42[Des-Arg9]-Bradykinin
CAS:<p>[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.</p>Fórmula:C44H61N11O10Pureza:98%Cor e Forma:SolidPeso molecular:904.02[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Fórmula:C74H112N22O18SPureza:98%Cor e Forma:SolidPeso molecular:1629.88Substance P, Free Acid
CAS:<p>Substance P, Free Acid is a synthetic analog of native Substance P, however, it lacks the biological activity exhibited by Substance P.</p>Fórmula:C63H97N17O14SPureza:98%Cor e Forma:SolidPeso molecular:1348.61GR 94800
CAS:<p>Potent and selective tachykinin NK2 receptor antagonist</p>Fórmula:C49H61N9O8Pureza:98%Cor e Forma:SolidPeso molecular:904.082Tienoxolol FA
<p>Tienoxolol FA, a beta-blocker for treating heart disease, hypertension, and ischemia.</p>Fórmula:C22H30N2O7SPureza:97.05% - 98.85%Cor e Forma:SoildPeso molecular:466.55ARL 15849XX
CAS:<p>ARL 15849XX, a CCK-8 analog, is a novel anti-obesity agent.</p>Fórmula:C47H60N8O13SPureza:98%Cor e Forma:SolidPeso molecular:977.09G-Protein antagonist peptide
CAS:<p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>Fórmula:C57H64N12O9SPureza:98%Cor e Forma:SolidPeso molecular:1093.27GRK-IN-1
CAS:<p>4-Amino-5-(bromomethyl)-2-methylpyrimidine used in vitamin B1 analogs and esters synthesis.</p>Fórmula:C6H10Br3N3Cor e Forma:SolidPeso molecular:363.87919(S)-HETE
CAS:<p>19-HETE, a CYP450 arachidonic acid metabolite from kidneys, consists of 70% (S) and 30% (R) isomers and dilates renal vessels.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.473Guanylin(human)
CAS:<p>Peptide that activates gut guanylyl cyclase, secreted by GI mucosa, regulates water and electrolytes in gut and kidneys.</p>Fórmula:C58H87N15O21S4Pureza:98%Cor e Forma:SolidPeso molecular:1458.65A3AR modulator 1
<p>MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.</p>Fórmula:C23H25IN4Cor e Forma:SolidPeso molecular:484.38[Des-Arg10]-HOE I40 TFA
<p>[Des-Arg10]-HOE I40 TFA is a potent antagonist of the bradykinin B1 receptor.</p>Fórmula:C53H77N15O12S·xC2HF3O2Cor e Forma:Solidγ1-MSH
CAS:<p>Endogenous melanocortin MC3 receptor agonist (pKi = 7.46) that displays ~ 40-fold selectivity over MC4.</p>Fórmula:C72H97N21O14SPureza:98%Cor e Forma:SolidPeso molecular:1512.765-hydroxy Propranolol
CAS:<p>5-hydroxy Propranolol, a propranolol metabolite, is formed in the liver via P450 2D6.</p>Fórmula:C16H21NO3Cor e Forma:SolidPeso molecular:275.348Navafenterol saccharinate
CAS:<p>AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).</p>Fórmula:C45H47N7O9S3Cor e Forma:SolidPeso molecular:926.09Cloprostenol isopropyl ester
CAS:<p>(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.</p>Fórmula:C25H35ClO6Cor e Forma:SolidPeso molecular:466.99O-2172
CAS:<p>O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).</p>Fórmula:C14H16Cl2O2Cor e Forma:SolidPeso molecular:287.18Cortistatin-8 acetate
<p>Cortistatin-8 acetate: synthetic corticosteroid analog, GHS-R antagonist; doesn't affect acyl GH release or hesperidin response.</p>Fórmula:C49H72N12O11S2Pureza:99.01%Cor e Forma:SoildPeso molecular:1069.3Pancreatic Polypeptide, bovine
CAS:<p>Agonist at Y4 neuropeptide Y receptors.</p>Fórmula:C186H287N53O56S2Pureza:98%Cor e Forma:SolidPeso molecular:4225.78TAK-615
CAS:<p>TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.</p>Fórmula:C25H22FNO4Pureza:99.73%Cor e Forma:SolidPeso molecular:419.44ABT-702
CAS:<p>ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.</p>Fórmula:C22H19BrN6OPureza:99.57%Cor e Forma:SoildPeso molecular:463.33Alcaftadine carboxylic acid
CAS:<p>Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis.</p>Fórmula:C19H21N3O2Cor e Forma:SolidPeso molecular:323.39GR 64349
CAS:<p>Potent NK2 agonist, EC50=3.7 nM in rat colon; >1000x selectivity over NK1, >300x over NK3; effective in vivo.</p>Fórmula:C42H68N10O11SPureza:98%Cor e Forma:SolidPeso molecular:921.12Urocortin, rat
CAS:<p>Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.</p>Fórmula:C206H338N62O64Pureza:98%Cor e Forma:SolidPeso molecular:4707.26GRK2-IN-1 hydrochloride (2055990-90-2 free base)
<p>GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).</p>Fórmula:C24H26ClFN4O4Pureza:98%Cor e Forma:SolidPeso molecular:488.94Alprostadil ethyl ester
CAS:<p>Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.</p>Fórmula:C22H38O5Cor e Forma:SolidPeso molecular:382.53Hemokinin 1, human
CAS:<p>Endogenous P-like compound, NK1 receptor agonist; IC50: NK1-1.8 nM, NK3-370 nM, NK2-480 nM; boosts B-cell growth, antiapoptotic, lowers blood pressure in vivo.</p>Fórmula:C54H84N14O14SPureza:98%Cor e Forma:SolidPeso molecular:1185.4INCB3344 R-isomer
<p>INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.</p>Fórmula:C29H34F3N3O6Pureza:98%Cor e Forma:SolidPeso molecular:577.59Dipentylone hydrochloride
CAS:<p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>Fórmula:C14H20ClNO3Pureza:99.94%Cor e Forma:SolidPeso molecular:285.77Jmv 167
CAS:<p>Jmv 167 is an antagonist of the Cholecystokinin receptor.</p>Fórmula:C51H68N8O14SPureza:98%Cor e Forma:SolidPeso molecular:1049.21PG106
CAS:<p>Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.</p>Fórmula:C51H69N13O9Pureza:98%Cor e Forma:SolidPeso molecular:1008.19APJ receptor agonist 10
CAS:<p>APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.</p>Fórmula:C26H36N7O6SCor e Forma:SolidPeso molecular:574.67
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