CymitQuimica logo
GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

Exibir 18 mais subcategorias

Foram encontrados 5352 produtos de "GPCR/Proteína-G"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • (+)-OSU 6162
    Targetmol
    + Info

    (+)-OSU 6162

    CAS:
    <p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>
    Fórmula:C15H23NO2S
    Pureza:98.19%
    Cor e Forma:Soild
    Peso molecular:281.41

    Ref: TM-T60027

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    TCMCB07 TFA

    <p>TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in</p>
    Fórmula:C63H87N15O11·xC2HF3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1230.46 (free base)

    Ref: TM-T80541

  • Obestatin(rat)
    Targetmol
    + Info

    Obestatin(rat)

    CAS:
    <p>Endogenous peptide that suppresses food intake and body weight-gain</p>
    Fórmula:C114H174N34O31
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2516.81

    Ref: TM-TP2279

  • AC-263093
    Targetmol
    + Info

    AC-263093

    CAS:
    <p>AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.</p>
    Fórmula:C8H8Br2N4
    Pureza:99.78%
    Cor e Forma:Soild
    Peso molecular:319.98

    Ref: TM-T83651

  • LP 12 hydrochloride
    Targetmol
    + Info

    LP 12 hydrochloride

    CAS:
    <p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>
    Fórmula:C32H40ClN3O
    Cor e Forma:Solid
    Peso molecular:518.14

    Ref: TM-T37073

  • Avorelin
    Targetmol
    + Info

    Avorelin

    CAS:
    <p>Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.</p>
    Fórmula:C65H85N17O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1296.48

    Ref: TM-T26692

  • GB-6
    Targetmol
    + Info

    GB-6

    CAS:
    <p>GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due to</p>
    Fórmula:C32H45N11O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:711.77

    Ref: TM-T80266

  • Apadenoson TFA
    Targetmol
    + Info

    Apadenoson TFA

    <p>Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.</p>
    Fórmula:C25H31F3N6O8
    Pureza:98.08%
    Cor e Forma:Soild
    Peso molecular:600.55

    Ref: TM-T26641L

  • Fenoldopam
    Targetmol
    + Info

    Fenoldopam

    CAS:
    <p>Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).</p>
    Fórmula:C16H16ClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:305.76

    Ref: TM-T22779

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    NI-0701

    <p>NI-0701 is a humanized antibody targeting CCL5/RANTES.</p>
    Pureza:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:145.5kDa

    Ref: TM-T77486

  • 1,8-Cineole
    Targetmol
    + Info

    1,8-Cineole

    CAS:
    <p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>
    Fórmula:C10H18O
    Pureza:97.44% - 97.44%
    Cor e Forma:Solid
    Peso molecular:154.25

    Ref: TM-T1714

  • Fasitibant chloride
    Targetmol
    + Info

    Fasitibant chloride

    CAS:
    <p>Fasitibant chloride, a potent B2R blocker, alleviates pain and swelling in arthritis.</p>
    Fórmula:C36H49Cl3N6O6S
    Cor e Forma:Solid
    Peso molecular:800.23

    Ref: TM-T38544

  • Lobeline sulfate
    Targetmol
    + Info

    Lobeline sulfate

    CAS:
    <p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>
    Fórmula:C22H29NO6S
    Pureza:98%
    Cor e Forma:White Powder
    Peso molecular:435.54

    Ref: TM-T22357

  • [Nle11]-Substance P
    Targetmol
    + Info

    [Nle11]-Substance P

    CAS:
    <p>'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'</p>
    Fórmula:C64H100N18O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1329.59

    Ref: TM-TP1831

  • A6770
    Targetmol
    + Info

    A6770

    CAS:
    <p>A6770 inhibits S1P lyase, causing [3H]dhS1P build-up in IT-79MTNC3 cells (EC50 &lt;0.01 μM); less effective with vitamin B6 (EC50 &lt;100 μM).</p>
    Fórmula:C6H8N2O2
    Cor e Forma:Solid
    Peso molecular:140.142

    Ref: TM-T36833

  • Latanoprost lactone diol
    Targetmol
    + Info

    Latanoprost lactone diol

    CAS:
    <p>Latanoprost lactone diol, a key intermediate for synthesizing Latanoprost (a prostaglandin F2α analogue), lowers IOP by activating FP receptors.</p>
    Fórmula:C18H24O4
    Pureza:98%
    Cor e Forma:White Or Almost White Crystalline Powder
    Peso molecular:304.38

    Ref: TM-T11821

  • [Des-Arg9]-Bradykinin
    Targetmol
    + Info

    [Des-Arg9]-Bradykinin

    CAS:
    <p>[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.</p>
    Fórmula:C44H61N11O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:904.02

    Ref: TM-T7645

  • Prostaglandin F1α
    Targetmol
    + Info

    Prostaglandin F1α

    CAS:
    <p>Prostaglandin F1α (PGF1α) is a lipid mediator and an endogenous metabolite of prostacyclin, regulate smooth muscle contraction.</p>
    Fórmula:C20H36O5
    Cor e Forma:Solid
    Peso molecular:356.5

    Ref: TM-T37919

  • APJ receptor agonist 10
    Targetmol
    + Info

    APJ receptor agonist 10

    CAS:
    <p>APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.</p>
    Fórmula:C26H36N7O6S
    Cor e Forma:Solid
    Peso molecular:574.67

    Ref: TM-T203502

  • GLP-2(1-33)(human)
    Targetmol
    + Info

    GLP-2(1-33)(human)

    CAS:
    GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.
    Fórmula:C165H254N44O55S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3766.19

    Ref: TM-TP1157

  • Urocortin, rat
    Targetmol
    + Info

    Urocortin, rat

    CAS:
    <p>Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.</p>
    Fórmula:C206H338N62O64
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4707.26

    Ref: TM-TP1020

  • Pasireotide pamoate
    Targetmol
    + Info

    Pasireotide pamoate

    CAS:
    <p>Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.</p>
    Fórmula:C81H82N10O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1435.58

    Ref: TM-T12369

  • Pancreatic Polypeptide, human
    Targetmol
    + Info

    Pancreatic Polypeptide, human

    CAS:
    <p>Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.</p>
    Fórmula:C185H287N53O54S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4181.71

    Ref: TM-TP1137

  • NPC 567
    Targetmol
    + Info

    NPC 567

    CAS:
    <p>NPC 567 is an antagonist of the bradykinin receptor.</p>
    Fórmula:C60H87N19O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1282.48

    Ref: TM-T21060

  • G-Protein antagonist peptide
    Targetmol
    + Info

    G-Protein antagonist peptide

    CAS:
    <p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>
    Fórmula:C57H64N12O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1093.27

    Ref: TM-TP1902

  • JNJ-10181457 (hydrochloride)
    Targetmol
    + Info

    JNJ-10181457 (hydrochloride)

    CAS:
    <p>JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrations</p>
    Fórmula:C20H30Cl2N2O
    Cor e Forma:Solid
    Peso molecular:385.37

    Ref: TM-T37220

  • (±)5(6)-EET
    Targetmol
    + Info

    (±)5(6)-EET

    CAS:
    <p>5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.</p>
    Fórmula:C20H32O3
    Cor e Forma:Solid
    Peso molecular:320.473

    Ref: TM-T36070

  • MRS-1706
    Targetmol
    + Info

    MRS-1706

    CAS:
    <p>MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.</p>
    Fórmula:C27H29N5O5
    Pureza:99.00%
    Cor e Forma:Solid
    Peso molecular:503.55

    Ref: TM-T16136

  • GLP-1R Antagonist 1
    Targetmol
    + Info

    GLP-1R Antagonist 1

    CAS:
    <p>GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).</p>
    Fórmula:C16H11ClF6N4O2
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:440.73

    Ref: TM-T15387

  • Alprostadil ethyl ester
    Targetmol
    + Info

    Alprostadil ethyl ester

    CAS:
    <p>Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.</p>
    Fórmula:C22H38O5
    Cor e Forma:Solid
    Peso molecular:382.53

    Ref: TM-T29908

  • Cholecystokinin Octapeptide, desulfated
    Targetmol
    + Info

    Cholecystokinin Octapeptide, desulfated

    CAS:
    <p>Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) is an octapeptide composed of 8 amino acids from cholecystokinin-8.</p>
    Fórmula:C49H62N10O13S2
    Pureza:97.12%
    Cor e Forma:Solid
    Peso molecular:1063.21

    Ref: TM-TP2204

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Uroguanylin (human) TFA

    <p>Uroguanylin (human) (TFA) is the natural ligand for the guanylate cyclase C (GCC) receptor expressed in metastatic colorectal cancer tumors. In animal models of human colon cancer, Uroguanylin (human) (TFA) demonstrates antitumor activity.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TP3207

  • Apigenin 6,8-di-C-α-L-arabinopyranoside
    Targetmol
    + Info

    Apigenin 6,8-di-C-α-L-arabinopyranoside

    CAS:
    <p>Apigenin 6,8-di-C-alpha-L-arabinopyranoside is a useful organic compound for research related to life sciences.</p>
    Fórmula:C25H26O13
    Cor e Forma:Solid
    Peso molecular:534.47

    Ref: TM-T124311

  • BAM(8-22)
    Targetmol
    + Info

    BAM(8-22)

    CAS:
    <p>Potent MRGPRX1 agonist peptide; first found in bovine adrenal glands. Non-opioid, lacking met-enkephalin motif. EC50: 8-150 nM.</p>
    Fórmula:C91H127N25O23S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1971.22

    Ref: TM-TP1914

  • Leukotriene B4 Ethanolamide
    Targetmol
    + Info

    Leukotriene B4 Ethanolamide

    CAS:
    <p>LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.</p>
    Fórmula:C22H37NO4
    Cor e Forma:Solid
    Peso molecular:379.541

    Ref: TM-T37619

  • Apelin-36(human)
    Targetmol
    + Info

    Apelin-36(human)

    CAS:
    Endogenous APJ agonist, EC50=20nM, regulates cardiovascular function, fluid balance, and feeding; blocks certain HIV strains.
    Fórmula:C184H297N69O43S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4195.87

    Ref: TM-TP2093

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    CCG258208 hydrochloride

    <p>GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) &amp; GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.</p>
    Cor e Forma:Solid

    Ref: TM-T35875

  • (Ala13)-Apelin-13 acetate
    Targetmol
    + Info

    (Ala13)-Apelin-13 acetate

    <p>(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.</p>
    Fórmula:C65H111N23O18S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1534.79

    Ref: TM-T35374L

  • Pancreatic Polypeptide, bovine
    Targetmol
    + Info

    Pancreatic Polypeptide, bovine

    CAS:
    <p>Agonist at Y4 neuropeptide Y receptors.</p>
    Fórmula:C186H287N53O56S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4225.78

    Ref: TM-TP1731

  • Ecraprost
    Targetmol
    + Info

    Ecraprost

    CAS:
    <p>Ecraprost is used as a prodrug of prostaglandin E1.</p>
    Fórmula:C28H48O6
    Cor e Forma:Solid
    Peso molecular:480.68

    Ref: TM-T25362

  • Dipentylone hydrochloride
    Targetmol
    + Info

    Dipentylone hydrochloride

    CAS:
    <p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>
    Fórmula:C14H20ClNO3
    Pureza:99.94%
    Cor e Forma:Solid
    Peso molecular:285.77

    Ref: TM-T205977

  • IRL-3630
    Targetmol
    + Info

    IRL-3630

    CAS:
    <p>IRL 3460 is an enantiomer.</p>
    Fórmula:C31H40N4O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:596.74

    Ref: TM-T25541

  • Misoprostol acid
    Targetmol
    + Info

    Misoprostol acid

    CAS:
    <p>Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.</p>
    Fórmula:C21H36O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:368.51

    Ref: TM-T12047

  • Lisuride maleate
    Targetmol
    + Info

    Lisuride maleate

    CAS:
    <p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>
    Fórmula:C24H30N4O5
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:454.52

    Ref: TM-T8775

  • D-Epinephrine
    Targetmol
    + Info

    D-Epinephrine

    CAS:
    <p>D-Epinephrine: a hormone and drug, boosts heart rate, muscle blood flow, pupil size, and sugar levels in stress responses.</p>
    Fórmula:C9H13NO3
    Cor e Forma:Solid
    Peso molecular:183.2

    Ref: TM-T31383

  • Antisauvagine-30
    Targetmol
    + Info

    Antisauvagine-30

    CAS:
    <p>CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells &amp; stress-related responses in mice.</p>
    Fórmula:C161H274N48O46S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3650.29

    Ref: TM-TP2091

  • SB 201146
    Targetmol
    + Info

    SB 201146

    CAS:
    <p>SB 201146 is a leukotriene B4 antagonist with high affinity.</p>
    Fórmula:C30H35LiN2O5S
    Cor e Forma:Solid
    Peso molecular:542.61

    Ref: TM-T28667

  • (+)-Cloprostenol sodium
    Targetmol
    + Info

    (+)-Cloprostenol sodium

    CAS:
    <p>Cloprostenol sodium is a water-soluble PGF2α analog and FP receptor agonist, promoting luteolysis in rats and hamsters.</p>
    Fórmula:C22H28ClNaO6
    Cor e Forma:Solid
    Peso molecular:446.9

    Ref: TM-T29245

  • Parstatin(mouse)
    Targetmol
    + Info

    Parstatin(mouse)

    CAS:
    <p>Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.</p>
    Fórmula:C189H326N58O57S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4419.19

    Ref: TM-TP1966

  • Gemeprost
    Targetmol
    + Info

    Gemeprost

    CAS:
    <p>Gemeprost treats obstetric bleeding and induces abortion up to 24 weeks when used with mifepristone.</p>
    Fórmula:C23H38O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:394.54

    Ref: TM-T20855