GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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2-Pyridylethylamine dihydrochloride
CAS:<p>2-Pyridylethylamine dihydrochloride is a Histamine H1 receptor agonist.</p>Fórmula:C7H12Cl2N2Pureza:99.42%Cor e Forma:SolidPeso molecular:195.09Lurasidone hydrochloride
CAS:Lurasidone HCl: Atypical antipsychotic, treats schizophrenia & bipolar, affects dopamine, serotonin & adrenergic receptors.Fórmula:C28H36N4O2S·HClPureza:99.51%Cor e Forma:SolidPeso molecular:529.14Ditolylguanidine
CAS:<p>Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).</p>Fórmula:C15H17N3Pureza:98.42%Cor e Forma:White To Pinkish Solid PowderPeso molecular:239.32Cariprazine hydrochloride
CAS:<p>Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)</p>Fórmula:C21H33Cl3N4OPureza:99.78% - >99.99%Cor e Forma:SolidPeso molecular:463.87Alizapride hydrochloride
CAS:<p>Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.</p>Fórmula:C16H21N5O2·HClPureza:99.35% - 99.48%Cor e Forma:CoaPeso molecular:351.83Hemopressin (rat) acetate(568588-77-2 free base)
<p>Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.</p>Fórmula:C5H81N13O14Pureza:99.37%Cor e Forma:SolidPeso molecular:1148.31Ondansetron hydrochloride
CAS:<p>Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation</p>Fórmula:C18H19N3O·HClPureza:99.78%Cor e Forma:White PowderPeso molecular:329.82Empagliflozin
CAS:<p>Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.</p>Fórmula:C23H27ClO7Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:450.91Ki16425
CAS:Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.Fórmula:C23H23ClN2O5SPureza:97.6% - 97.78%Cor e Forma:SolidPeso molecular:474.96Bradykinin (acetate)
CAS:<p>Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system.</p>Fórmula:C52H77N15O13Pureza:>99.99%Cor e Forma:SolidPeso molecular:1120.26LGnRH-III, lamprey acetate(147859-97-0 free base)
<p>LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion</p>Fórmula:C61H78N18O16Pureza:99.66%Cor e Forma:SolidPeso molecular:1319.38Dobutamine tartrate
CAS:<p>Dobutamine tartrate is a cardiotonic.</p>Fórmula:C22H29NO9Cor e Forma:SolidPeso molecular:451.472Alizapride
CAS:<p>Alizapride is an antagonist of dopamine receptor. Alizapride can be used in human digestive disorders which is a potent antiemetic [1] [3].</p>Fórmula:C16H21N5O2Cor e Forma:SolidPeso molecular:315.37RO1138452
CAS:<p>RO1138452 (CAY10441) blocks prostacyclin receptor; orally active, high affinity (Ki: 1.5 nM), analgesic in rats (2-20 mg/kg).</p>Fórmula:C19H23N3OPureza:97.01% - 99.34%Cor e Forma:SolidPeso molecular:309.41M40 acetate(143896-17-7 free base)
<p>M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29)</p>Fórmula:C96H149N23O26Pureza:99.88%Cor e Forma:SolidPeso molecular:2041.38BAY 41-8543
CAS:<p>BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).</p>Fórmula:C21H21FN8OPureza:99.86%Cor e Forma:SolidPeso molecular:420.44Lys-[Des-Arg9]Bradykinin,TFA
<p>Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2</p>Fórmula:C54H75F6N13O15Pureza:97.35%Cor e Forma:SolidPeso molecular:1260.24LUN42518 HCl 47142-51-8(free base)
<p>LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.</p>Fórmula:C17H20ClN3OPureza:99.96%Cor e Forma:SolidPeso molecular:317.81Dexmedetomidine
CAS:<p>Dexmedetomidine: a central alpha-2 adrenergic agonist for general anesthesia.</p>Fórmula:C13H16N2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:200.28BD1063 dhydrochloride
CAS:BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).Fórmula:C13H20Cl4N2Pureza:99.52% - ≥95%Cor e Forma:SolidPeso molecular:346.12Avexitide
CAS:<p>Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.</p>Fórmula:C149H234N40O47SPureza:98% - 99.65%Cor e Forma:SolidPeso molecular:3369.76NNC-0640
CAS:<p>NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.</p>Fórmula:C29H31N7O4SPureza:97.04%Cor e Forma:SolidPeso molecular:573.67Derenofylline
CAS:<p>Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)</p>Fórmula:C18H20N4OPureza:98.09%Cor e Forma:SolidPeso molecular:308.38Parmodulin 2
CAS:<p>ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).</p>Fórmula:C17H17BrN2O2Pureza:97.35% - 99.95%Cor e Forma:SolidPeso molecular:361.23Loxapine hydrochloride
CAS:<p>Loxapine hydrochloride, an oral anti-psychotic, inhibits dopamine and blocks 5-HT receptors.</p>Fórmula:C18H19Cl2N3OCor e Forma:SolidPeso molecular:364.27nifenalol.HCl
CAS:<p>Nifenalol.HCl(INPEA) is a antagonist of β-adrenergic receptor.</p>Fórmula:C11H17ClN2O3Pureza:99.96%Cor e Forma:SolidPeso molecular:260.72Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Fórmula:C20H24N2OSCor e Forma:SolidPeso molecular:340.48L-DOPA methyl ester (hydrochloride)
CAS:<p>L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.</p>Fórmula:C10H14ClNO4Pureza:98.69% - 99.81%Cor e Forma:White SolidPeso molecular:247.675FAUC-365
CAS:FAUC-365 is a D3 dopamine receptor agonist.Fórmula:C23H25Cl2N3OSPureza:99.62%Cor e Forma:SolidPeso molecular:462.44Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Fórmula:C24H22N4O5SPureza:98.89% - 99.15%Cor e Forma:SolidPeso molecular:478.52Ajmalicine hydrochloride
CAS:<p>Ajmalicine hydrochloride is a potent α1-adrenoceptor blocker, non-competitive nicotine receptor inhibitor, anti-hypertensive, and sedative. IC50: 72.3 μM.</p>Fórmula:C21H25ClN2O3Cor e Forma:SolidPeso molecular:388.89Fluparoxan HCl
CAS:<p>Fluparoxan is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent α2/α1 selectivity (2630 fold).</p>Fórmula:C10H11ClFNO2Cor e Forma:SolidPeso molecular:231.65Vilanterol trifenatate
CAS:<p>Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)</p>Fórmula:C44H49Cl2NO7Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:774.77A-381393
CAS:<p>A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).</p>Fórmula:C20H24N4Pureza:99.00%Cor e Forma:SolidPeso molecular:320.43Batefenterol
CAS:<p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>Fórmula:C40H42ClN5O7Pureza:97.94% - 98.4%Cor e Forma:SolidPeso molecular:740.24Eltoprazine dihydrochloride
CAS:<p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>Fórmula:C12H18Cl2N2O2Pureza:99.64%Cor e Forma:SolidPeso molecular:293.19ACTH (1-17) acetate
<p>ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).</p>Fórmula:C97H149N29O25SPureza:98.53%Cor e Forma:SolidPeso molecular:2153.47ARC-239
CAS:<p>ARC-239 is an agonist of α2-adrenergic receptor.</p>Fórmula:C24H29N3O3Cor e Forma:SolidPeso molecular:407.51Urotensin I acetate (83930-33-0 Free base)
Urotensin I acetate, CRF1/CRF2 agonist: pEC50s - hCRF1 11.46, hCRF2 9.36, rCRF2α 9.85; KIs - hCRF1 0.4 nM, rCRF2α 1.8 nM, mCRF2β 5.7 nM.Pureza:95.44% - 99.73%Cor e Forma:SolidPeso molecular:N/AGLP-1(7-36), amide
CAS:GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.Fórmula:C149H226N40O45Pureza:99.85%Cor e Forma:White PowderPeso molecular:3297.63Cetirizine Impurity B dihydrochloride
CAS:<p>Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.</p>Fórmula:C19H23Cl3N2O2Pureza:99.24%Cor e Forma:SolidPeso molecular:417.76S 38093 HCl
CAS:<p>S 38093 is a novel brain-penetrant antagonist/inverse agonist of H3 receptors.</p>Fórmula:C17H25ClN2O2Pureza:97.91%Cor e Forma:SolidPeso molecular:324.85THIQ
CAS:<p>THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).</p>Fórmula:C33H41ClN6O2Pureza:98.93%Cor e Forma:SolidPeso molecular:589.17Vilazodone Hydrochloride
CAS:<p>Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the</p>Fórmula:C26H27N5O2·HClPureza:99.56% - >99.99%Cor e Forma:SolidPeso molecular:477.99Pancreatic Polypeptide, rat acetate
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.Pureza:97.53%Cor e Forma:SolidPeso molecular:N/AZM241385
CAS:<p>ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.</p>Fórmula:C16H15N7O2Pureza:97.02% - 99.69%Cor e Forma:SolidPeso molecular:337.34Tozadenant
CAS:<p>Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)</p>Fórmula:C19H26N4O4SPureza:98%Cor e Forma:SolidPeso molecular:406.5SR 57227 hydrochloride
CAS:<p>SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.</p>Fórmula:C10H14ClN3·HClPureza:99.89%Cor e Forma:SolidPeso molecular:248.15Xanthine amine congener hydrochloride
CAS:<p>Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.</p>Fórmula:C21H29ClN6O4Cor e Forma:SolidPeso molecular:464.95CP 376395
CAS:<p>CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.</p>Fórmula:C21H30N2OPureza:99.86% - 99.94%Cor e Forma:SolidPeso molecular:326.48
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