GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.946 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5360 produtos de "GPCR/Proteína-G"
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Somatostatin acetate
<p>Somatostatin acetate is an endogenously secreted inhibitor of cell proliferation with potential antitumor activity for the study of cancer and neurological disorders.</p>Pureza:99.11%Cor e Forma:Odour SolidEnrasentan
CAS:<p>Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.</p>Fórmula:C29H30O8Pureza:97.9% - 98.39%Cor e Forma:SolidPeso molecular:506.54BP 897 hydrochloride
CAS:<p>BP 897: potent D3 agonist (Ki: 0.92 nM), weak D2 antagonist (Ki: 61 nM), low affinity for D1/D4.</p>Fórmula:C26H32ClN3O2Pureza:99.42%Cor e Forma:SolidPeso molecular:454Pizotifen Malate
CAS:<p>Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.</p>Fórmula:C19H21NS·C4H6O5Pureza:>99.99%Cor e Forma:SolidPeso molecular:429.53AB928
CAS:<p>AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1].</p>Fórmula:C23H22N8OPureza:98.09% - >99.99%Cor e Forma:SolidPeso molecular:426.47Mirabegron
CAS:<p>Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.</p>Fórmula:C21H24N4O2SPureza:99.64%Cor e Forma:Light Yellow To Yellow SolidPeso molecular:396.51Carteolol hydrochloride
CAS:<p>Carteolol hydrochloride is a nonselective beta-blocker used to treat hypertension, arrhythmias, angina, and glaucoma.</p>Fórmula:C16H24N2O3·HClPureza:99.84% - 99.91%Cor e Forma:SolidPeso molecular:328.83Mefexamide hydrochloride
CAS:<p>Mefexamide hydrochloride is a central stimulant.</p>Fórmula:C15H25ClN2O3Pureza:99.95%Cor e Forma:SolidPeso molecular:316.83Astemizole
CAS:<p>Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.</p>Fórmula:C28H31FN4OPureza:98.24% - 99.67%Cor e Forma:White Crystals SolidPeso molecular:458.57Bufotenidine hydrochloride(487-91-2 Free base)
CAS:<p>Bufotenidine hydrochloride(487-91-2 Free base) is a natural product for research related to life sciences.</p>Fórmula:C13H19ClN2OPureza:99.88%Cor e Forma:SolidPeso molecular:254.76Naftidrofuryl oxalate
CAS:<p>Naftidrofuryl oxalate treats peripheral/cerebral vascular issues, boosts cell oxidation, is spasmolytic, and may block 5HT-2 serotonin receptors.</p>Fórmula:C26H35NO7Pureza:97.12% - 98.38%Cor e Forma:SolidPeso molecular:473.56Sertraline hydrochloride
CAS:<p>Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.</p>Fórmula:C17H18Cl3NPureza:99.12% - 99.89%Cor e Forma:Solid PowderPeso molecular:342.691GTS-21 dihydrochloride
CAS:<p>GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.</p>Fórmula:C19H20N2O2·2HClPureza:98.54% - >99.99%Cor e Forma:SolidPeso molecular:381.3Tropisetron hydrochloride
CAS:<p>Tropisetron hydrochloride (Tropisetron HCl) is a selective, competitive serotonin 5-HT3 receptor antagonist, with antinauseant and antiemetic activities.</p>Fórmula:C17H21ClN2O2Pureza:99.72% - 99.83%Cor e Forma:SolidPeso molecular:320.82Labetalol
CAS:<p>Labetalol: mixed alpha/beta blocker for hypertension, oral or IV; affected by CYP2C19 genetics.</p>Fórmula:C19H24N2O3Pureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:328.41Roluperidone
CAS:<p>Roluperidone (CYR-101) is a novel cyclic amide derivative.</p>Fórmula:C22H23FN2O2Pureza:96.46% - 97.77%Cor e Forma:SolidPeso molecular:366.43Spiperone
CAS:<p>Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.</p>Fórmula:C23H26FN3O2Pureza:99.34% - 99.91%Cor e Forma:SolidPeso molecular:395.47Efloxate
CAS:<p>Efloxate (Angorlisin), a vasodilator, is utilized in the treatment of chronic coronary insufficiency.</p>Fórmula:C19H16O5Pureza:99.66%Cor e Forma:SolidPeso molecular:324.33Tabernanthalog fumarate
CAS:<p>Tabernanthalog fumarate is a 5-HT2A agonist that promotes neuronal growth and reduces alcohol consumption in mice, producing antidepressant-like effects.</p>Fórmula:C18H22N2O5Pureza:99.83%Cor e Forma:SoildPeso molecular:346.38(R)-Terazosin
CAS:<p>R-Terazosin is the active R-enantiomer and potent α1-adrenoceptor antagonist (Ki: α1a 6.51 nM, α1b 1.01 nM, α1d 1.97 nM).</p>Fórmula:C19H25N5O4Pureza:98.87% - 98.96%Cor e Forma:SolidPeso molecular:387.43Ritodrine hydrochloride
CAS:<p>Ritodrine hydrochloride (NSC 291565), a phenethylamine derivative, reduces uterine contractions by increasing cAMP and decreasing calcium in myometrial cells.</p>Fórmula:C17H21NO3·HClPureza:99% - 99.52%Cor e Forma:SolidPeso molecular:323.82CB1 antagonist 2
CAS:<p>CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.</p>Fórmula:C17H12Cl3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:380.66Molindone hydrochloride
CAS:<p>Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.</p>Fórmula:C16H24N2O2·HClPureza:99% - 99.99%Cor e Forma:SolidPeso molecular:312.84JMV 2959 hydrochloride (925238-89-7 free base)
CAS:<p>JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.</p>Fórmula:C30H33ClN6O2Pureza:98.09%Cor e Forma:SolidPeso molecular:545.08Alarelin Acetate
CAS:<p>Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.</p>Fórmula:C56H78N16O12Pureza:99.81% - >99.99%Cor e Forma:White PowderPeso molecular:1167.34ML604086
CAS:<p>ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.</p>Fórmula:C27H32N4O4SPureza:99.91%Cor e Forma:SolidPeso molecular:508.632-(1-Piperazinyl)pyrimidine
CAS:<p>2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug.</p>Fórmula:C8H12N4Pureza:98.46%Cor e Forma:Liquid - Crystal - LumpPeso molecular:164.21Dexchlorpheniramine Maleate
CAS:<p>Dexchlorpheniramine Maleate, an antihistamine with anticholinergic effects, treats allergies like hay fever. It's the active isomer of chlorpheniramine.</p>Fórmula:C20H23ClN2O4Pureza:99.58%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:390.86Ogerin
CAS:<p>Ogerin: GPR68 modulator, blocks mice fear recall, A2A inverse agonist/antagonist (Ki 220 nM), weak 5-HT2B antagonist (Ki 736 nM).</p>Fórmula:C17H17N5OPureza:99.5% - 99.75%Cor e Forma:SolidPeso molecular:307.35Degarelix acetate(214766-78-6 free base)
CAS:<p>Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .</p>Fórmula:C84H107ClN18O18Pureza:98.66%Cor e Forma:SolidPeso molecular:1692.34Balovaptan
CAS:<p>Balovaptan (RG7314), a potent brain-penetrant hV1a receptor antagonist, Ki: 1 nM for hV1a, aids autism research.</p>Fórmula:C22H24ClN5OPureza:99.88%Cor e Forma:SolidPeso molecular:409.91Dipivefrin hydrochloride
CAS:<p>Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.</p>Fórmula:C19H27NO5·HClPureza:99.22% - 99.92%Cor e Forma:Less Gas With A Sweet Odor Colorless Gas With A Sweet OdorPeso molecular:387.9ONC206
CAS:<p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>Fórmula:C23H22F2N4OPureza:99.38% - 99.81%Cor e Forma:SolidPeso molecular:408.44Quercetin-3'-o-phosphate TEA
<p>Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA) is an adenosine A receptor antagonist that can be used to prevent and treat metabolic disorders.</p>Fórmula:C21H26NO10PPureza:95.63%Cor e Forma:SoildPeso molecular:483.41Fluphenazine dihydrochloride
CAS:<p>Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR. Fluphenazine can be used to probe effects and metabolic process.</p>Fórmula:C22H28Cl2F3N3OSPureza:99.23%Cor e Forma:Off-White SolidPeso molecular:510.44MRGPRX1 agonist 1
CAS:<p>MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM).</p>Fórmula:C23H21N3O4SPureza:99.95%Cor e Forma:SolidPeso molecular:435.5DSP-4 hydrochloride
CAS:<p>DSP-4 hydrochloride is a neurotoxin that degrades noradrenergic neurons in rats and crosses the blood-brain barrier.</p>Fórmula:C11H16BrCl2NPureza:99.9%Cor e Forma:SolidPeso molecular:313.06REV 5901A
CAS:<p>REV 5901A (REV 5901 HCl) is a leukotriene receptor antagonist and 5-LOX inhibitor with antimicrobial activity that attenuates the growth of colon cancer in mice</p>Fórmula:C22H26ClNO2Pureza:98.04%Cor e Forma:SoildPeso molecular:371.90Salbutamol
CAS:<p>Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。</p>Fórmula:C13H21NO3Pureza:91.59% - 99.9%Cor e Forma:White To Off-White Crystalline Solid SolidPeso molecular:239.31CYM50308
CAS:<p>CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).</p>Fórmula:C20H21F2N3O2SPureza:99.43% - 99.77%Cor e Forma:SolidPeso molecular:405.46PIT
CAS:<p>PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1.</p>Fórmula:C20H16N2O5SPureza:98.63%Cor e Forma:SolidPeso molecular:396.42Quetiapine hemifumarate
CAS:Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.Fórmula:C46H54N6O8S2Pureza:99.32% - >99.99%Cor e Forma:White Crystalline SolidPeso molecular:883.09Ciliobrevin D
CAS:<p>Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor.</p>Fórmula:C17H8Cl3N3O2Pureza:98.09%Cor e Forma:SolidPeso molecular:392.62Glycerol phenylbutyrate
CAS:<p>Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).</p>Fórmula:C33H38O6Pureza:98.54% - 99.74%Cor e Forma:SolidPeso molecular:530.65Benserazide hydrochloride
CAS:<p>Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.</p>Fórmula:C10H15N3O5·HClPureza:98.63% - 99.74%Cor e Forma:White Crystalline SolidPeso molecular:293.7Brefonalol HCl
<p>Brefonalol HCl, ADRA blocker for neurological/cardiovascular issues, treats angina, arrhythmias, hypertension.</p>Fórmula:C22H29ClN2O2Pureza:99.45%Cor e Forma:SolidPeso molecular:388.93Metoclopramide hydrochloride
CAS:<p>Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.</p>Fórmula:C14H22ClN3O2·HClPureza:99.99%Cor e Forma:White To Off-White PowderPeso molecular:336.26Tetrahydrozoline
CAS:<p>Tetrahydrozoline (Tetryzoline) is an alpha-adrenergic agonist that causes vasoconstriction and is widely used in the study of nasal and conjunctival congestion.</p>Fórmula:C13H16N2Pureza:97.85% - 99.77%Cor e Forma:SolidPeso molecular:200.28Paliperidone
CAS:<p>Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic.</p>Fórmula:C23H27FN4O3Pureza:95% - 99.08%Cor e Forma:Off White To Light Orange Coloured SolidPeso molecular:426.48CE3F4
CAS:<p>CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).</p>Fórmula:C11H10Br2FNOPureza:97.15% - 98.06%Cor e Forma:SolidPeso molecular:351.01
