GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.946 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5360 produtos de "GPCR/Proteína-G"
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[Leu15]-Gastrin I, human
CAS:<p>[Leu15]-Gastrin I, human is a variant of Gastrin I, modulating the binding of cholecystokinin to mucosal membranes.</p>Fórmula:C98H126N20O31Pureza:98.02% - 98.84%Cor e Forma:SolidPeso molecular:2080.16Olopatadine hydrochloride
CAS:<p>Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.</p>Fórmula:C21H23NO3·HClPureza:99.62% - 99.64%Cor e Forma:White SolidPeso molecular:373.87(S)-(-)-Atenolol
CAS:<p>(S)-(-)-Atenolol has beta-adrenergic blocking effects.</p>Fórmula:C14H22N2O3Pureza:99.31% - 99.81%Cor e Forma:SolidPeso molecular:266.34Rebamipide
CAS:<p>Rebamipide (OPC12759) is a drug enhancing gastric defense by stimulating COX2, prostaglandins, and mucus, while reducing TNF alpha and free radicals.</p>Fórmula:C19H15ClN2O4Pureza:99.48% - 99.61%Cor e Forma:White PowderPeso molecular:370.792',5'-Dideoxyadenosine
CAS:<p>2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).</p>Fórmula:C10H13N5O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:235.24Nepafenac
CAS:<p>Nepafenac (AHR 9434) is an NSAID that acts as a cyclooxygenase inhibitor.</p>Fórmula:C15H14N2O2Pureza:98.94% - 99.43%Cor e Forma:SolidPeso molecular:254.28ALLO-2
CAS:<p>ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.</p>Fórmula:C18H12F3N5OPureza:99.19%Cor e Forma:SolidPeso molecular:371.32AVN 322 free base
CAS:<p>AVN 322 free base is an orally available, selective and potent 5-HT6R antagonist for the study of neuropathic system disorders such as Alzheimer's disease (AD) and schizophrenia.</p>Fórmula:C17H19N5O2SPureza:99.24%Cor e Forma:SolidPeso molecular:357.43L-741626
CAS:<p>L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3</p>Fórmula:C20H21ClN2OPureza:98.57%Cor e Forma:SolidPeso molecular:340.85Dazmegrel HCl
<p>Dazmegrel HCl is a platelet thromboxane inhibitor used in the study of myocardial infarction and arrhythmias.</p>Fórmula:C16H18ClN3O2Pureza:98.30%Cor e Forma:SolidPeso molecular:319.79Carboprost tromethamine
CAS:<p>Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding</p>Fórmula:C25H47NO8Pureza:>99.99%Cor e Forma:SolidPeso molecular:489.64Loratadine
CAS:<p>Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria.</p>Fórmula:C22H23ClN2O2Pureza:99.71% - 99.98%Cor e Forma:White PowderPeso molecular:382.88Methoxamine hydrochloride
CAS:<p>Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.</p>Fórmula:C11H18ClNO3Pureza:99.84% - >99.99%Cor e Forma:Colorless Or White Plate-Like Crystals Or White Crystalline Powder SolidPeso molecular:247.719CB1 antagonist 2
CAS:<p>CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.</p>Fórmula:C17H12Cl3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:380.66Frovatriptan succinate hydrate
CAS:<p>Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.</p>Fórmula:C18H25N3O6Pureza:99.66%Cor e Forma:SolidPeso molecular:379.41INCB-9471
CAS:<p>INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.</p>Fórmula:C30H40F3N5O2Pureza:98.80%Cor e Forma:SolidPeso molecular:559.666Asenapine Maleate
CAS:<p>Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually.</p>Fórmula:C21H20ClNO5Pureza:99.28%Cor e Forma:SolidPeso molecular:401.84Ramelteon
CAS:<p>Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.</p>Fórmula:C16H21NO2Pureza:97.21% - 99.92%Cor e Forma:Crystalline SolidPeso molecular:259.34Nicergoline
CAS:<p>Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.</p>Fórmula:C24H26BrN3O3Pureza:98% - 99.80%Cor e Forma:SolidPeso molecular:484.39Tetrahydrozoline
CAS:<p>Tetrahydrozoline (Tetryzoline) is an alpha-adrenergic agonist that causes vasoconstriction and is widely used in the study of nasal and conjunctival congestion.</p>Fórmula:C13H16N2Pureza:97.85% - 99.77%Cor e Forma:SolidPeso molecular:200.28N6-Ethyladenosine
CAS:<p>N6-Ethyladenosine is an adenosine derivative, acts as an agonist of Adenosine receptor(hA1AR and hA3AR with Kis of 4.9 and 4.7 nM , respectively).</p>Fórmula:C12H17N5O4Pureza:99.96%Cor e Forma:SolidPeso molecular:295.29Tolnapersine TFA
<p>Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.</p>Fórmula:C23H27F3N2O3Pureza:99.14%Cor e Forma:SoildPeso molecular:436.47Benztropine mesylate
CAS:<p>Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON</p>Fórmula:C21H25NO·CH4SO3Pureza:98.41% - 99.96%Cor e Forma:White Crystalline Powder; Odourless Or Almost OdourlessPeso molecular:403.53SR59230A
CAS:<p>SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).</p>Fórmula:C23H29NO6Pureza:98.84%Cor e Forma:SolidPeso molecular:415.48Naftifine hydrochloride
CAS:<p>Naftifine HCl: synthetic antifungal; inhibits squalene epoxidase, disrupting fungal cell sterol synthesis.</p>Fórmula:C21H22ClNPureza:98.75% - 99.84%Cor e Forma:SolidPeso molecular:323.86BMY 25368 HCl
CAS:<p>BMY 25368 HCl is a competitive histamine H2 receptor antagonist that antagonizes gastric secretion stimulated by pentagastrin, ethacrynic choline, and food.</p>Fórmula:C19H26ClN3O3Pureza:98.73% - 99.81%Cor e Forma:SoildPeso molecular:379.88Timonacic
CAS:<p>Timonacic (Thioproline) has been used in trials studying the treatment of HIV Infections.</p>Fórmula:C4H7NO2SPureza:99.99%Cor e Forma:SolidPeso molecular:133.17Doxofylline
CAS:<p>Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7.</p>Fórmula:C11H14N4O4Pureza:99.958% - >99.99%Cor e Forma:SolidPeso molecular:266.25Lamotrigine
CAS:<p>Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.</p>Fórmula:C9H7Cl2N5Pureza:99.76% - 99.95%Cor e Forma:White To Pale Cream-Colored Powder Crystals From Isopropanol SolidPeso molecular:256.09Sarizotan 2HCl
CAS:<p>Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.</p>Fórmula:C22H23Cl2FN2OPureza:98.83%Cor e Forma:SoildPeso molecular:421.34CYM50308
CAS:<p>CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).</p>Fórmula:C20H21F2N3O2SPureza:99.43% - 99.77%Cor e Forma:SolidPeso molecular:405.46Vapreotide acetate
CAS:<p>Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).</p>Fórmula:C59H74N12O11S2Pureza:99.89%Cor e Forma:SolidPeso molecular:1191.42Prostaglandin E1
CAS:<p>Alprostadil (PGE1) is a natural vasodilator that also inhibits platelets and induces bronchodilation, used in erectile dysfunction treatment.</p>Fórmula:C20H34O5Pureza:99.78% - >99.99%Cor e Forma:SolidPeso molecular:354.48Paroxetine hydrochloride
CAS:<p>Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.</p>Fórmula:C19H21ClFNO3Pureza:98% - 99.99%Cor e Forma:White Crystalline PowderPeso molecular:365.826CCR2-RA-[R]
CAS:<p>CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).</p>Fórmula:C18H19ClFNO3Pureza:99.7%Cor e Forma:SolidPeso molecular:351.8Glycerol phenylbutyrate
CAS:<p>Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).</p>Fórmula:C33H38O6Pureza:98.54% - 99.74%Cor e Forma:SolidPeso molecular:530.65SEP-363856 hydrochloride
CAS:<p>SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.</p>Fórmula:C9H14ClNOSPureza:99.86% - 99.99%Cor e Forma:SolidPeso molecular:219.73ONC206
CAS:<p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>Fórmula:C23H22F2N4OPureza:99.38% - 99.81%Cor e Forma:SolidPeso molecular:408.44Bromperidol
CAS:<p>Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.</p>Fórmula:C21H23BrFNO2Pureza:99.89%Cor e Forma:Tan SolidPeso molecular:420.32GR 103691
CAS:<p>GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM).</p>Fórmula:C30H35N3O3Pureza:98.94% - 99.29%Cor e Forma:SolidPeso molecular:485.62ML-109
CAS:<p>ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)</p>Fórmula:C31H29N3O5Pureza:98.63%Cor e Forma:SolidPeso molecular:523.58Mirtazapine
CAS:<p>Mirtazapine is a unique tetracyclic antidepressant, may cause temporary liver enzyme elevation, and is linked to rare liver injury.</p>Fórmula:C17H19N3Pureza:99.98%Cor e Forma:SolidPeso molecular:265.35EMPA
CAS:<p>EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM</p>Fórmula:C23H26N4O4SPureza:99.11%Cor e Forma:SolidPeso molecular:454.54Tegaserod maleate
CAS:<p>Tegaserod (SDZ-HTF-919), a 5-HT4 agonist for irritable bowel syndrome, was withdrawn by FDA on March 30, 2007, due to heart risk concerns.</p>Fórmula:C20H27N5O5Pureza:98% - 99.06%Cor e Forma:White PowderPeso molecular:417.46Chlorpheniramine maleate
CAS:<p>Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.</p>Fórmula:C20H23ClN2O4Pureza:99.64% - 99.98%Cor e Forma:Odorless White Crystalline Solid Or White Powder With A Bitter TastePeso molecular:390.87Somatostatin acetate
<p>Somatostatin acetate is an endogenously secreted inhibitor of cell proliferation with potential antitumor activity for the study of cancer and neurological disorders.</p>Pureza:99.11%Cor e Forma:Odour SolidLesopitron HCl
CAS:<p>Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.</p>Fórmula:C15H22Cl2N6Pureza:97.05% - 99.89%Cor e Forma:SoildPeso molecular:357.28Ozagrel
CAS:<p>Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of</p>Fórmula:C13H12N2O2Pureza:97.90% - 99.38%Cor e Forma:White PowderPeso molecular:228.25Ifenprodil Tartrate
CAS:<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Fórmula:C21H27NO2C4H6O6Pureza:99.02% - 99.55%Cor e Forma:SolidPeso molecular:400.49Fenclozine Maleate
CAS:<p>Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain.</p>Fórmula:C45H47ClN2O12Pureza:98.47%Cor e Forma:SoildPeso molecular:843.314
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