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CAS 50-04-4

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Cortisone, 21-acetate

Description:
Cortisone, 21-acetate, also known as cortisone acetate, is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from cortisone, a naturally occurring steroid hormone produced by the adrenal cortex. The chemical structure of cortisone acetate includes a ketone group and an acetate ester, which enhances its solubility and bioavailability. This compound is typically administered in the form of injections or topical formulations to treat various conditions, including arthritis, allergies, and skin disorders. Cortisone acetate works by mimicking the effects of cortisol, a hormone that regulates metabolism and immune response, thereby reducing inflammation and suppressing the immune system. Its pharmacological effects can lead to side effects such as weight gain, mood changes, and increased susceptibility to infections when used long-term. As with other corticosteroids, careful monitoring is essential during treatment to mitigate potential adverse effects. Overall, cortisone acetate is a valuable therapeutic agent in managing inflammatory and autoimmune conditions.
Formula:C23H30O6
InChI:InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
InChI key:InChIKey=ITRJWOMZKQRYTA-RFZYENFJSA-N
SMILES:C[C@@]12[C@]([C@]3([C@](C(=O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]
Synonyms:
  • (8Alpha,9Beta,14Beta)-17-Hydroxy-3,11,20-Trioxopregn-4-En-21-Yl Acetate
  • (8Xi,9Xi,14Xi)-17-Hydroxy-3,11,20-Trioxopregn-4-En-21-Yl Acetate
  • 17,21-Dihydroxypregn-4-Ene-3,11,20-Trione
  • 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21 acetate
  • 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate
  • 21-Acetate De Cortisone
  • 21-Acetato De Cortisona
  • 21-Acetoxy-17-hydroxypregn-4-ene-3,11,20-trione
  • 21-Acetoxy-17α-hydroxy-3,11,20-triketopregnene-4
  • 21-Acetoxy-17α-hydroxypregn-4-ene-3,11,20-trione
  • See more synonyms
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