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CAS 127-79-7

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Sulfamerazine

Description:
Sulfamerazine is a sulfonamide antibiotic that belongs to the class of sulfa drugs, which are synthetic antimicrobial agents. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, a vital nutrient for bacteria. The chemical structure of sulfamerazine includes a sulfonamide group, which is essential for its antibacterial activity. It is typically administered in the form of its sodium salt and is known for its moderate solubility in water. Sulfamerazine is primarily used in veterinary medicine, particularly for treating infections in livestock and pets. Its pharmacological properties include a relatively long half-life, allowing for less frequent dosing. However, like other sulfonamides, it may cause side effects such as allergic reactions or gastrointestinal disturbances in some individuals. Due to the emergence of antibiotic resistance, the use of sulfamerazine and similar antibiotics is often approached with caution, emphasizing the need for responsible use in both human and veterinary medicine.
Formula:C11H12N4O2S
InChI:InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
InChI key:InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N
SMILES:S(NC=1N=C(C)C=CN1)(=O)(=O)C2=CC=C(N)C=C2
Synonyms:
  • 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine
  • 2-Sulfa-4-methylpyrimidine
  • 2-Sulfanilamido-4-methylpyrimidine
  • 2-Sulfanylamido-4-methylpyrimidine
  • 2-Sulphanilamido-4-methylpyrimidine
  • 2632Rp
  • 2643Rp
  • 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide
  • 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
  • A 310
  • See more synonyms
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