CAS 130-01-8: senecionine

Description:Senecionine is a pyrrolizidine alkaloid, a class of compounds known for their complex bicyclic structures and potential toxicity. It is primarily derived from plants in the Asteraceae family, particularly those in the genus Senecio. Senecionine is characterized by its molecular formula, which typically includes nitrogen and various carbon and hydrogen atoms, contributing to its unique structural properties. This compound is known for its hepatotoxic effects, which can lead to liver damage upon ingestion, making it a subject of concern in herbal medicine and toxicology. Senecionine can also exhibit mutagenic properties, raising further health concerns. Its presence in certain plants can lead to accidental poisoning in livestock and humans, particularly when consumed in large quantities or over extended periods. As a result, understanding its chemical behavior, potential interactions, and effects on biological systems is crucial for assessing risks associated with exposure to this alkaloid.

Formula:C₁₈H₂₅NO₅

InChI:InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4-/t11-,14-,15-,18-/m1/s1

InChI key:InChIKey=HKODIGSRFALUTA-JTLQZVBZSA-N

SMILES:O=C1OC2CCN3CC=C(COC(=O)C(O)(C)C(C)CC1=CC)C32

Synonyms:
(15Z)-12-hydroxysenecionan-11,16-dione
(3Z,5R,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
12-Hydroxysenecionan-11,16-Dione
Aureine
NSC 89935
Senecionan-11,16-dione, 12-hydroxy-
Senecionin
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, [5R-(3Z,5R*,6R*,14aR*,14bR*)]-

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Senecionine REF: 11-1828CAS: 130-01-8	(HPLC) ≥95%	209.00 €	Mon 07 Apr 25
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)- REF: IN-DA000TUWCAS: 130-01-8	97.5%	470.00 €~636.00 €	Mon 14 Apr 25
Senecionine REF: 7W-GY5116CAS: 130-01-8	- - -	To inquire	Tue 15 Apr 25
Senecionine REF: 54-BUP04516CAS: 130-01-8	98.81%	594.00 €~1,201.00 €	Tue 15 Apr 25
Senecionine 100 µg/mL in Methanol:Water REF: 04-A16934000MW-100CAS: 130-01-8	- - -	To inquire	Tue 15 Apr 25
Senecionine REF: BP-BP1283CAS: 130-01-8	95%~99%	118.00 €~897.00 €	Tue 15 Apr 25
Pyrrolizidine alkaloids Mixture 661 100 µg/mL in Methanol REF: 04-A50000661MECAS: 101687-28-9 10285-06-0 10285-07-1 127-30-0 130-01-8 13268-67-2 15503-86-3 2318-18-5 303-33-3 303-34-4 38710-26-8 41093-89-4 480-54-6 480-81-9 520-68-3 570-19-4 6209-65-0 65582-53-8 72755-25-0 95462-14-9 95462-15-0	- - -	To inquire	Tue 15 Apr 25
Senecionine REF: 4Z-S-110001CAS: 130-01-8	- - -	To inquire	Mon 21 Apr 25
Senecionine-d3 REF: 4Z-S-110003CAS: 130-01-8	- - -	To inquire	Mon 21 Apr 25
Senecionine REF: TM-TQ0192CAS: 130-01-8	97.8% - 98.82%	66.00 €~818.00 €	Mon 21 Apr 25
Senecionine REF: 5G-89789CAS: 130-01-8	≥ 98.0 % (HPLC)	301.00 €~20,431.00 €	Mon 21 Apr 25
Senecionine-D3 REF: TR-S258652CAS: 130-01-8	- - -	584.00 €~4,000.00 €	Tue 22 Apr 25
Senecionine REF: TR-S258650CAS: 130-01-8	- - -	261.00 €~1,707.00 €	Fri 23 May 25
Senecionine REF: 3D-FS161593CAS: 130-01-8	Min. 95%	194.00 €~1,355.00 €	Tue 27 May 25