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CAS 1524-88-5

:

Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-

Description:
Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-, commonly known as a synthetic steroid, exhibits several notable characteristics. This compound is a derivative of progesterone, featuring modifications that enhance its biological activity and stability. The presence of a fluorine atom at the 6-position and hydroxyl groups at the 11 and 21 positions contribute to its pharmacological properties, potentially influencing its interaction with steroid receptors. The (1-methylethylidene)bis(oxy) moiety at the 16 and 17 positions suggests increased lipophilicity, which may affect its absorption and distribution in biological systems. This compound is often studied for its potential therapeutic applications, particularly in hormone replacement therapies and anti-inflammatory treatments. Its structural complexity and specific stereochemistry play a crucial role in determining its biological activity and efficacy. As with many steroids, understanding its pharmacokinetics and dynamics is essential for evaluating its safety and effectiveness in clinical settings.
Formula:C24H33FO6
InChI:InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
InChI key:InChIKey=POPFMWWJOGLOIF-XWCQMRHXSA-N
SMILES:C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C([C@@H](F)C4)=CC(=O)CC5)[H])[H])[H]
Synonyms:
  • (6α,11β,16α)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
  • 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
  • 33379
  • 6α-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregn-4-ene-3,20-dione
  • 6α-Fluoro-16α-hydroxyhydrocortisone 16,17-acetonide
  • Alondra F
  • Cordran
  • Drenison
  • Drocort
  • Fluadrenolone
  • See more synonyms
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Found 10 products.