CAS: 179324-69-7 - Bortezomib

Formula: C₁₉H₂₅BN₄O₄

InChI: InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1

InChI key: InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N

SMILES: O=C(NC(C(=O)NC(B(O)O)CC(C)C)CC=1C=CC=CC1)C2=NC=CN=C2

Synonyms:

• B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
• Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
• Boronic acid, [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-
• Boronic acid, [3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, [S-(R*,S*)]-
• Bortezomib for research
• Bortizomib
• Brotezamide
• Dpba
• Ldp 341
• Mg 341
• Mln 341
• N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide
• N-[(1S)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-D-phenylalaninamide
• NSC 681239
• PS 341 (pharmaceutical)
• Ps 314
• Ps 341
• Radiciol
• Velcade
• [(1R)-3-Methyl-1-[[(2S)-1-Oxo-3-Phenyl-2-[(Pyrazinylcarbonyl)Amino]Propyl]Amino]Butyl]-Boronic Acid

Bortezomib

CAS: 179324-69-7

• Formula: C₁₉H₂₅BN₄O₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 384.24

Bortezomib, 98%

CAS: 179324-69-7

A potent, highly selective and reversible inhibitor of the 20S proteasome, Bortezomib is used as …

• Formula: C₁₉H₂₅BN₄O₄
• Purity: 98%
• Color and Shape: White to off-white, Powder or crystals or crystalline powder
• Molecular weight: 384.24

Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-

CAS: 179324-69-7

• Formula: C₁₉H₂₅BN₄O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 384.2372

Bortezomib

CAS: 179324-69-7

• Formula: C₁₉H₂₅BN₄O₄
• Purity: 98% (nmr) (Typical Value in Batch COA)
• Color and Shape: white solid
• Molecular weight: 384.24g/mol

Bortezomib

CAS: 179324-69-7

• Formula: C₁₉H₂₅BN₄O₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder or solid
• Molecular weight: 384.24

Bortezomib Trimer ((1R,2S)-Bortezomib Trimer)

CAS: 179324-69-7390800-88-1

• Formula: C₅₇H₆₉B₃N₁₂O₉
• Color and Shape: White To Off-White Solid
• Molecular weight: 1098.68

Bortezomib

CAS: 179324-69-7

Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.

• Formula: C₁₉H₂₅BN₄O₄
• Purity: 100% - 99.97%
• Color and Shape: Yellow Solid
• Molecular weight: 384.24

(1R,2S)-Bortezomib

CAS: 179324-69-7

• Formula: C₁₉H₂₅BN₄O₄
• Molecular weight: 384.24

Bortezomib

CAS: 179324-69-7

Stability Hygroscopic and Moisture Sensitive Applications Bortezomib is the first proteasome inhibitor to be approved …

• Formula: C₁₉H₂₅BN₄O₄
• Color and Shape: White To Off-White
• Molecular weight: 384.24

Bortezomib-D8 (Major)

CAS: 179324-69-7

Applications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA …

• Formula: C₁₉H₁₇D₈BN₄O₄
• Color and Shape: Off-White
• Molecular weight: 392.29

Bortezomib - Bio-X ™

CAS: 179324-69-7

Bortezomib is a selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of …

• Formula: C₁₉H₂₅BN₄O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 384.24 g/mol

Bortezomib

CAS: 179324-69-7

Selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of protein breakdown affects …

• Formula: C₁₉H₂₅BN₄O₄
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 384.24 g/mol