CAS 2135-17-3
:Flumetasone
Description:
Flumetasone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological applications. It is characterized by its potent glucocorticoid activity, which helps in reducing inflammation and alleviating symptoms associated with various skin conditions, such as eczema and psoriasis. Flumetasone is typically formulated in topical preparations, allowing for localized treatment with minimal systemic absorption. Its chemical structure features a fluorinated steroid backbone, which enhances its anti-inflammatory efficacy compared to non-fluorinated corticosteroids. The substance is known for its relatively low systemic side effects when applied topically, making it a preferred choice in dermatology. Additionally, flumetasone exhibits a favorable pharmacokinetic profile, with a rapid onset of action and a duration of effect that supports its therapeutic use. As with all corticosteroids, caution is advised regarding prolonged use, as it may lead to skin atrophy or other local adverse effects. Overall, flumetasone serves as an effective option in managing inflammatory skin disorders.
Formula:C22H28F2O5
InChI:InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key:InChIKey=WXURHACBFYSXBI-GQKYHHCASA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:- (6Alpha,11Beta,16Alpha)-6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- (6Alpha,8Xi,11Beta,14Xi,16Alpha)-6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- (6α,11β,16α)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- 6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- 6-Alpha,9-Alpha-Difluoro-11-Beta,17-Alpha,21-Trihydroxy-16-Alpha-Methylpregna-1,4-Diene-3,20-Dione
- 6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
- 6α,9α-Difluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
- 6α,9α-Difluoro-16α-methylprednisolone
- 6α-Fluorodexamethasone
- 6α-Fluorodexamethazone
- Anaprime
- Aniprime
- Aniprome
- Cortexillar
- Flucort
- Flucorticin
- Flumetasone
- Flumethason
- Flutamethasone
- Fluvet
- Methagon
- NSC 5402
- NSC 54702
- Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)-
- Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl-
- Rs 2177
- U 10974
- See more synonyms
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Found 12 products.
Flumetasone
CAS:Formula:C22H28F2O5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:410.46Flumethasone
CAS:<p>Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.</p>Formula:C22H28F2O5Purity:99.38% - 99.96%Color and Shape:White Crystalline PowderMolecular weight:410.45Flumethasone
CAS:Formula:C22H28F2O5Purity:≤ 0.5%Color and Shape:White or to almost white powderMolecular weight:410.45GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Color and Shape:Mixture6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (Flumetasone)
CAS:Controlled ProductFormula:C22H28F2O5Color and Shape:NeatMolecular weight:410.45Flumethasone
CAS:Controlled Product<p>Applications A glucocorticoid. An anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Formula:C22H28F2O5Color and Shape:White To Off-WhiteMolecular weight:410.45Flumethasone-d3
CAS:Controlled Product<p>Applications Labelled Flumethasone (F455000). A glucocorticoid. An anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Formula:C22H25D3F2O5Color and Shape:NeatMolecular weight:413.47Flumethasone
CAS:Controlled Product<p>Fluorinated corticosteroid; anti-inflammatory; antipruritic; vasoconstrictor</p>Formula:C22H28F2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:410.45 g/mol
