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CAS 2152-44-5

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Betamethasone valerate

Description:
Betamethasone valerate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in dermatological preparations. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and psoriasis. The substance is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents like ethanol and acetone. Its chemical structure includes a steroid backbone with a valerate ester, which enhances its potency and duration of action compared to other corticosteroids. Betamethasone valerate is typically formulated in creams, ointments, and lotions for topical application, allowing for localized treatment with minimal systemic absorption. The compound is known for its relatively low side effect profile when used appropriately, although prolonged use can lead to skin atrophy and other local adverse effects. As with all corticosteroids, it is important to use betamethasone valerate under medical supervision to ensure safe and effective treatment.
Formula:C27H37FO6
InChI:InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1
InChI key:InChIKey=SNHRLVCMMWUAJD-SUYDQAKGSA-N
SMILES:C[C@@]12[C@@](OC(CCCC)=O)(C(CO)=O)[C@@H](C)C[C@]1([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • (11-beta,16-beta)-l)oxy)
  • (11Beta,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
  • (11β,16β)-9-Fluoro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
  • (8Xi,14Xi,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
  • 1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate
  • 17,21-Trihydroxy-16-Beta-Methylpregna-1,4-Diene-3,20-Dione-9-Fluoro-11-Bet
  • 17-Valerate
  • 9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
  • 9-Fluoro-11beta,17,21-trihydroxy-16bet
  • 9α-Fluoro-11β,21-dihydroxy-16β-methyl-17α-valeryloxypregna-1,4-diene-3,20-dione
  • See more synonyms
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Found 18 products.