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CAS 25122-57-0

:

Clobetasone butyrate

Description:
Clobetasone butyrate is a synthetic corticosteroid used primarily for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and dermatitis. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Clobetasone butyrate exhibits a moderate potency compared to other corticosteroids, making it suitable for use in sensitive areas of the skin. Its mechanism of action involves the inhibition of inflammatory mediators and the modulation of immune responses. The compound is generally well-tolerated, though potential side effects may include skin irritation or atrophy with prolonged use. As with other corticosteroids, it is important to use clobetasone butyrate as directed to minimize risks associated with long-term use, such as adrenal suppression. Overall, clobetasone butyrate serves as an effective option in the management of inflammatory skin disorders.
Formula:C22H26ClFO4
InChI:InChI=1/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
InChI key:InChIKey=FBRAWBYQGRLCEK-AVVSTMBFSA-N
SMILES:O(C(CCC)=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)(C(=O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • (16Beta)-21-Chloro-9-Fluoro-16-Methyl-3,11,20-Trioxopregna-1,4-Dien-17-Yl Butanoate
  • (16β)-21-Chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione
  • 21-Chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione butyrate
  • 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
  • 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione butyrate
  • Butyric acid, ester with 21-chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione
  • CCl 5537
  • Cci 5537
  • Clobetasone 17-butyrate
  • Clobetasone butyrate [USAN:JAN]
  • See more synonyms
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