CAS 3093-35-4: Halcinonide
Description:Halcinonide is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is classified as a topical corticosteroid and is often employed in the treatment of various skin conditions, including eczema and psoriasis. Halcinonide functions by inhibiting the release of inflammatory mediators and reducing the proliferation of immune cells in the affected area, thereby alleviating symptoms such as redness, swelling, and itching. The compound is typically formulated in ointment or cream form for direct application to the skin. Its potency is considered moderate compared to other corticosteroids, making it suitable for treating localized skin disorders. As with other corticosteroids, prolonged use can lead to potential side effects, including skin thinning and systemic absorption, particularly if used over large areas or under occlusive dressings. Therefore, it is essential to use Halcinonide under medical supervision and adhere to prescribed dosages to minimize risks while effectively managing skin conditions.
Formula:C24H32ClFO5
InChI:InChI=1S/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI key:InChIKey=MUQNGPZZQDCDFT-JNQJZLCISA-N
SMILES:O=C1C=C2CCC3C4CC5OC(OC5(C(=O)CCl)C4(C)CC(O)C3(F)C2(C)CC1)(C)C
- Synonyms:
- (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (4bR,6bS,9aR,10aS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (6bS,9aR)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- 21-Chloro-9-Alpha-Fluoro-11-Beta-Hydroxy-16-Alpha,17-Alpha-Isopropylidenedioxypregn-4-Ene-3,20-Dione
- 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
- Adcortin
- Alcinonide
- Halciderm
- Halcimat
- See more synonyms
- Halog
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11β,16α,17-trihydroxy-, cyclic 16,17-acetal with acetone
- Sq 18566
- Halcinonide