CAS 3093-35-4
:Halcinonide
Description:
Halcinonide is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is classified as a topical corticosteroid and is often employed in the treatment of various skin conditions, including eczema and psoriasis. Halcinonide functions by inhibiting the release of inflammatory mediators and reducing the proliferation of immune cells in the affected area, thereby alleviating symptoms such as redness, swelling, and itching. The compound is typically formulated in ointment or cream form for direct application to the skin. Its potency is considered moderate compared to other corticosteroids, making it suitable for treating localized skin disorders. As with other corticosteroids, prolonged use can lead to potential side effects, including skin thinning and systemic absorption, particularly if used over large areas or under occlusive dressings. Therefore, it is essential to use Halcinonide under medical supervision and adhere to prescribed dosages to minimize risks while effectively managing skin conditions.
Formula:C24H32ClFO5
InChI:InChI=1/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15?,16?,17?,19-,21?,22?,23?,24-/m1/s1
InChI key:InChIKey=MUQNGPZZQDCDFT-JNQJZLCISA-N
SMILES:C(CCl)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)CC5)[H])[H]
Synonyms:- (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (4bR,6bS,9aR,10aS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (6bS,9aR)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- 21-Chloro-9-Alpha-Fluoro-11-Beta-Hydroxy-16-Alpha,17-Alpha-Isopropylidenedioxypregn-4-Ene-3,20-Dione
- 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
- Adcortin
- Alcinonide
- Halciderm
- Halcimat
- Halog
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11β,16α,17-trihydroxy-, cyclic 16,17-acetal with acetone
- Sq 18566
- Halcinonide
- 2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
- halcort
- 20-dione,21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy-pregn-4-ene-cyc
- Halcinonide CP2000
- 21-Chloro-9α-fluoro-11β-hydroxy-16α,17α-(isopropylidenebisoxy)pregn-4-ene-3,20-dione
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-
- Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy, cyclic-16,17-acetal with acetone
- lic16,17-acetalwithacetone
- See more synonyms
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Found 12 products.
Halcinonide
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C24H32ClFO5Color and Shape:White Off-White Crystalline PowderMolecular weight:454.19223(1S,2S,4R,8S,9S,11S,12R,13S)-8-(2-chloroacetyl)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-17-en-16-one
CAS:Formula:C24H32ClFO5Purity:98%Color and Shape:SolidMolecular weight:454.9593Halcinonide
CAS:Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.Formula:C24H32ClFO5Purity:99.32% - 99.93%Color and Shape:SolidMolecular weight:454.96GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Color and Shape:MixtureHalcinonide
CAS:Formula:C24H32ClFO5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:454.96Halcinonide
CAS:Controlled Product<p>Applications Anti-inflammatory (topical).<br>References Kirshbaum, J., et al.: Anal. Profiles Drug Subs., 8, 251 (1979),<br></p>Formula:C24H32ClFO5Color and Shape:NeatMolecular weight:454.96Halcinonide
CAS:<p>Halcinonide is a potent topical corticosteroid, which is a synthetically derived compound from hydrocortisone. It operates by penetrating the cell membranes and binding to cytoplasmic receptors, leading to a subsequent translocation to the nucleus where it modulates genetic expression. This action results in diminished synthesis of pro-inflammatory cytokines, thereby exerting strong anti-inflammatory, antipruritic, and vasoconstrictive effects.</p>Formula:C24H32ClFO5Purity:Min. 95%Color and Shape:PowderMolecular weight:454.96 g/molHalcinonide Hydroxide
CAS:Controlled ProductFormula:C24H32ClFO6Color and Shape:NeatMolecular weight:470.959










