CAS 33564-31-7
:Diflorasone diacetate
Description:
Diflorasone diacetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological applications. It is characterized by its potent glucocorticoid activity, which helps in reducing inflammation and alleviating symptoms associated with various skin conditions. The compound is typically formulated as a topical ointment or cream, allowing for localized treatment of conditions such as eczema, psoriasis, and dermatitis. Diflorasone diacetate exhibits a high affinity for glucocorticoid receptors, leading to its effectiveness in modulating immune responses and inhibiting the release of pro-inflammatory mediators. Its chemical structure includes two acetate groups, which enhance its lipophilicity, facilitating better skin penetration and absorption. While it is effective in managing inflammation, caution is advised regarding prolonged use, as it may lead to skin atrophy or other local side effects. Overall, diflorasone diacetate is a valuable therapeutic agent in dermatology, offering significant benefits in the management of inflammatory skin disorders.
Formula:C26H32F2O7
InChI:InChI=1/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(32)6-7-23(19,4)25(18,28)22(34-14(2)30)11-24(17,5)26(13,21(33)12-29)35-15(3)31/h6-7,9,13,17-18,20,22,29H,8,10-12H2,1-5H3/t13-,17-,18-,20-,22-,23-,24-,25-,26-/m0/s1
InChI key:InChIKey=BOBLHFUVNSFZPJ-JOYXJVLSSA-N
SMILES:C(COC(C)=O)(=O)[C@]1(OC(C)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
Synonyms:- (6Alpha,11Beta,16Beta)-6,9-Difluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Diacetate
- (6α,11β,16β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
- 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-diacetate
- 6alpha-Fluorobetamethasone-17,21 diacetate
- Apexicon
- Apexicon e
- Brn 2318163
- Dermaflor
- Diacort
- Diflorasone 17,21-diacetate
- Diflorasone di(acetate)
- Difulal
- Florone
- Florone E
- Maxiflor
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6alpha,11beta,16beta)-
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16β)-
- Psorcon
- Psorcon E
- Soriflor
- U 34865
- Unii-7W2J09Scwx
- Diflorasone diacetate
- 6a,9-difluoro-11b,17,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17,21-diacetate
- DIFLORASONEDIACETATE,USP
- 6α,9-difluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-diacetate
- 6 ALPHA,9-DIFLUORO-11 BETA,17,21-TRIHYDROXY-16 BETA-METHYLPREGNA-1,4-DIENE-3,20-DIONE-17,21-DIACETE
- U 24865
- 17,21-Diacetyloxy-6α,9-difluoro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione
- pregna-1,4-diene-3,20-dione,17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-me
- (6-alpha,11-beta,16-beta)-thyl
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
Diflorasone Diacetate
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C26H32F2O7Color and Shape:PowderMolecular weight:494.21161GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Controlled Product- 105102-22-5
- 1177-87-3
- 124-94-7
- 13609-67-1
- 14484-47-0
- 1524-88-5
- 2135-17-3
- 2152-44-5
- 25122-46-7
- 25122-57-0
- 3093-35-4
- 33564-31-7
- 356-12-7
- 378-44-9
- 3801-06-7
- 3870-07-3
- 426-13-1
- 4419-39-0
- 50-02-2
- 50-03-3
- 50-04-4
- 50-23-7
- 50-24-8
- 51022-69-6
- 51333-22-3
- 514-36-3
- 53-06-5
- 5534-09-8
- 5593-20-4
- 57524-89-7
- 66734-13-2
- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Color and Shape:MixtureDiflorasone Diacetate
CAS:Diflorasone Diacetate, a topical glucocorticoid, has immunosuppressive and anti-inflammatory properties.Formula:C26H32F2O7Color and Shape:CrystalsMolecular weight:494.53Diflorasone Diacetate
CAS:Controlled ProductFormula:C26H32F2O7Color and Shape:NeatMolecular weight:494.52Diflorasone Diacetate
CAS:Controlled ProductFormula:C26H32F2O7Color and Shape:NeatMolecular weight:494.52Diflorasone Diacetate
CAS:Controlled ProductApplications An anti-inflammatory and anti-itching corticosteroid usually present in topical creams.
References Dikunets, M., et al.: J. Anal. Chem., 64, 832 (2009), Maccaroni, E., et al.: Steroids, 74, 102 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Formula:C26H32F2O7Color and Shape:NeatMolecular weight:494.52Diflorasone diacetate
CAS:Controlled ProductDiflorasone diacetate is a synthetic corticosteroid used to treat inflammatory skin diseases. It is chemically stable and has been shown in vitro to inhibit the growth of cancer cells. Diflorasone diacetate has also been shown to have an anti-inflammatory effect that may be due to its ability to inhibit the production of prostaglandins, which are hormones that cause inflammation. Diflorasone diacetate has also been shown to reduce the development of erythema (redness) in mice with skin inflammation. Clinical trials have demonstrated that diflorasone diacetate is effective for treating inflammatory skin disorders such as atopic dermatitis and psoriasis.
Formula:C26H32F2O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:494.52 g/mol
