CAS 33564-31-7: Diflorasone diacetate
Description:Diflorasone diacetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological applications. It is characterized by its potent glucocorticoid activity, which helps in reducing inflammation and alleviating symptoms associated with various skin conditions. The compound is typically formulated as a topical ointment or cream, allowing for localized treatment of conditions such as eczema, psoriasis, and dermatitis. Diflorasone diacetate exhibits a high affinity for glucocorticoid receptors, leading to its effectiveness in modulating immune responses and inhibiting the release of pro-inflammatory mediators. Its chemical structure includes two acetate groups, which enhance its lipophilicity, facilitating better skin penetration and absorption. While it is effective in managing inflammation, caution is advised regarding prolonged use, as it may lead to skin atrophy or other local side effects. Overall, diflorasone diacetate is a valuable therapeutic agent in dermatology, offering significant benefits in the management of inflammatory skin disorders.
Formula:C26H32F2O7
InChI:InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1
InChI key:InChIKey=BOBLHFUVNSFZPJ-JOYXJVLSSA-N
SMILES:O=C1C=CC2(C(=C1)C(F)CC3C4CC(C)C(OC(=O)C)(C(=O)COC(=O)C)C4(C)CC(O)C32F)C
- Synonyms:
- (6Alpha,11Beta,16Beta)-6,9-Difluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Diacetate
- (6α,11β,16β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
- 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-diacetate
- 6alpha-Fluorobetamethasone-17,21 diacetate
- Apexicon
- Apexicon e
- Brn 2318163
- Dermaflor
- Diacort
- Diflorasone 17,21-diacetate
- See more synonyms
- Diflorasone di(acetate)
- Difulal
- Florone
- Florone E
- Maxiflor
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6alpha,11beta,16beta)-
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16β)-
- Psorcon
- Psorcon E
- Soriflor
- U 34865
- Unii-7W2J09Scwx
