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CAS 3801-06-7

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Fluorometholone acetate

Description:
Fluorometholone acetate is a synthetic corticosteroid primarily used in ophthalmic formulations for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various eye conditions, such as allergic conjunctivitis and post-operative inflammation. The compound features a fluorinated steroid structure, which enhances its potency and reduces systemic side effects compared to non-fluorinated corticosteroids. Fluorometholone acetate is typically administered as an eye drop solution, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of inflammatory mediators and the modulation of immune responses. The substance is generally well-tolerated, but potential side effects may include increased intraocular pressure and cataract formation with prolonged use. As with any corticosteroid, careful monitoring is essential to mitigate risks associated with long-term therapy. Overall, fluorometholone acetate is a valuable therapeutic agent in the management of ocular inflammation.
Formula:C24H31FO5
InChI:InChI=1/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1
InChI key:InChIKey=YRFXGQHBPBMFHW-SBTZIJSASA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@](OC(C)=O)(C(C)=O)CC3)[H])(C[C@H](C)C=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • (6Alpha,11Beta)-9-Fluoro-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
  • (6Alpha,11Beta)-9-Fluoro-11-Hydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
  • (6α,11β)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-methylpregna-1,4-diene-3,20-dione
  • 6α-Methyl-9α-fluoro-17-acetoxy-21-deoxyprednisolone
  • 6α-Methyl-9α-fluoro-21-desoxyprednisolone-17-acetate
  • 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
  • Ai3-52814
  • Eflone
  • Flarex
  • Fluorometholone 17-acetate
  • See more synonyms
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