CAS 3801-06-7

Fluorometholone acetate

Description:

Fluorometholone acetate is a synthetic corticosteroid primarily used in ophthalmic formulations for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various eye conditions, such as allergic conjunctivitis and post-operative inflammation. The compound features a fluorinated steroid structure, which enhances its potency and reduces systemic side effects compared to non-fluorinated corticosteroids. Fluorometholone acetate is typically administered as an eye drop solution, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of inflammatory mediators and the modulation of immune responses. The substance is generally well-tolerated, but potential side effects may include increased intraocular pressure and cataract formation with prolonged use. As with any corticosteroid, careful monitoring is essential to mitigate risks associated with long-term therapy. Overall, fluorometholone acetate is a valuable therapeutic agent in the management of ocular inflammation.

Formula: C₂₄H₃₁FO₅

InChI: InChI=1/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1

InChI key: InChIKey=YRFXGQHBPBMFHW-SBTZIJSASA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@](OC(C)=O)(C(C)=O)CC3)[H])(C[C@H](C)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (6Alpha,11Beta)-9-Fluoro-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
• (6Alpha,11Beta)-9-Fluoro-11-Hydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (6α,11β)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-methylpregna-1,4-diene-3,20-dione
• 6α-Methyl-9α-fluoro-17-acetoxy-21-deoxyprednisolone
• 6α-Methyl-9α-fluoro-21-desoxyprednisolone-17-acetate
• 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
• Ai3-52814
• Eflone
• Flarex
• Fluorometholone 17-acetate
• Nsc 47438
• Oxylone acetate
• Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6alpha,11beta)-
• Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6α,11β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-6α-methyl-, 17-acetate
• Tobrasone
• U 17,323
• Unii-9I50C3I3Ok
• FLUROMETHOLONE ACETATE
• fluorometholone acetate
• Nolpitantium
• 17-(Acetyloxy)-9-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione
• Eflone USP/EP/BP
• FLUOROMETHOLONE ACETATE (200 MG)
• 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
• FLUOROMETHALONE ACETATE
• 9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate

Fluorometholone Acetate

CAS: 3801-06-7

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₄H₃₁FO₅

Color and Shape: White Powder

Molecular weight: 418.5

Ref: 45-1278109

Eflone

CAS: 3801-06-7

Formula: C₂₄H₃₁FO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 418.4983

Ref: IN-DA00BXNQ

Fluorometholone Acetate

CAS: 3801-06-7

Fluorometholone Acetate

Purity: ≥98%

Molecular weight: 418.5g/mol

Ref: 54-BUP11720

Fluorometholone acetate

Controlled Product

CAS: 3801-06-7

Formula: C₂₄H₃₁FO₅

Color and Shape: Neat

Molecular weight: 418.50

Ref: 04-C13793600

Fluorometholone Acetate

CAS: 3801-06-7

Color and Shape: Neat

Ref: 86-MM0870.01

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Controlled Product

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Color and Shape: Colourless

Ref: 04-A50000094ME

Fluorometholone Acetate

CAS: 3801-06-7

Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

Formula: C₂₄H₃₁FO₅

Purity: 99.76%

Color and Shape: Solid

Molecular weight: 418.50

Ref: TM-T6503

Fluorometholone Acetate

Controlled Product

CAS: 3801-06-7

Applications Fluorometholone Acetate is a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthalmol., 100, 640 (1982), Tokunaga, H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),

Formula: C₂₄H₃₁FO₅

Color and Shape: Off White To Light Yellow

Molecular weight: 418.5

Ref: TR-F593150

Fluorometholone acetate

Controlled Product

CAS: 3801-06-7

Fluorometholone acetate is a fluorinated corticosteroid that is used in ophthalmology to treat eye disorders. It has been shown to reduce intraocular pressure in patients with glaucoma and other eye diseases. Fluorometholone acetate inhibits the activity of the glucocorticoid receptor, which prevents it from binding to DNA and altering gene expression. This leads to a decrease in inflammatory responses by decreasing the production of cytokines and chemokines that are involved in inflammation. Fluorometholone acetate also binds to other receptors, such as the mineralocorticoid receptor, which may lead to its use as a potential biomarker for infectious diseases.

Formula: C₂₄H₃₁FO₅

Purity: Min. 95%

Molecular weight: 418.5 g/mol

Ref: 3D-FF23441