CAS 426-13-1: Fluorometholone
Description:Fluorometholone is a synthetic corticosteroid primarily used in ophthalmic formulations for its anti-inflammatory properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various eye conditions, such as allergic conjunctivitis and post-operative inflammation. The chemical structure of fluorometholone includes a fluorine atom, which enhances its potency and reduces systemic side effects compared to other corticosteroids. It is typically administered as an eye drop solution, allowing for localized treatment with minimal systemic absorption. Fluorometholone exhibits a relatively low solubility in water, which can influence its formulation and delivery methods. The substance is known for its effectiveness in managing ocular inflammation while maintaining a favorable safety profile, making it a valuable option in ophthalmology. As with all corticosteroids, its use should be monitored to avoid potential side effects, including increased intraocular pressure and potential for cataract formation with prolonged use.
Formula:C22H29FO4
InChI:InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChI key:InChIKey=FAOZLTXFLGPHNG-KNAQIMQKSA-N
SMILES:O=C1C=CC2(C(=C1)C(C)CC3C4CCC(O)(C(=O)C)C4(C)CC(O)C32F)C
- Synonyms:
- (6α,11β)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
- 21-Desoxy-9α-fluoro-6-methylprednisolone
- 6α-Methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione
- 6α-Methyl-9α-fluoro-21-desoxyprednisolone
- 9α-Fluoro-11β,17α-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione
- Cortilet
- Delmeson
- Efflumidex
- FML
- FML Forte
- See more synonyms
- FML Liquifilm
- Fluaton
- Fluaton PVA
- Flumetholon
- Flumetholone
- Fluor-Op
- Fluormetholon
- Fluorometholon
- Fluorometholone
- Fluorometolona
- Fml Sop
- Loticort
- Nsc-33001
- Oxylone
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-6α-methyl-
- U 8614
- Ursnon
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6α,11β)-
