CAS 4419-39-0: Beclomethasone
Description:Beclomethasone is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is commonly administered in the form of inhalers, nasal sprays, or topical formulations to treat conditions such as asthma, allergic rhinitis, and various skin disorders. The substance functions by inhibiting the release of inflammatory mediators, thereby reducing swelling and irritation in affected tissues. Beclomethasone has a relatively low systemic bioavailability when inhaled, which minimizes potential side effects compared to systemic corticosteroids. Its chemical structure features a steroid backbone with specific functional groups that contribute to its potency and selectivity for glucocorticoid receptors. The compound is generally well-tolerated, although long-term use may lead to side effects such as adrenal suppression or local irritation. As with any medication, it is essential to use beclomethasone under medical supervision to ensure appropriate dosing and to monitor for any adverse effects.
Formula:C22H29ClO5
InChI:InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key:InChIKey=NBMKJKDGKREAPL-DVTGEIKXSA-N
SMILES:O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)CO)C4(C)CC(O)C32Cl)C
- Synonyms:
- (11β,16β)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8S,10S,11S,13S,16S)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- 4419-39-0
- 9-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
- 9-Chloro-11β,17,21-trihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione
- 9-Chloro-16β-methylprednisolone
- 9α-Chloro-16β-methylprednisolone
- Beclometason
- Beclometasona
- Beclometasone
- See more synonyms
- Beclometasone 17,21-Dipropionate
- Becolvent
- Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-
- Pregna-1,4-diene-3,20-dione, 9-chloro-11β,17,21-trihydroxy-16β-methyl-
