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CAS 50-03-3

:

Hydrocortisone acetate

Description:
Hydrocortisone acetate, with the CAS number 50-03-3, is a synthetic corticosteroid that is commonly used for its anti-inflammatory and immunosuppressive properties. It is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents such as ethanol and acetone. The substance is often utilized in topical formulations, such as creams and ointments, to treat various skin conditions, including eczema and dermatitis, as well as in injectable forms for systemic effects. Hydrocortisone acetate functions by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands, thereby reducing inflammation and suppressing the immune response. Its pharmacological effects include vasoconstriction, inhibition of leukocyte infiltration, and suppression of cytokine production. While generally well-tolerated, potential side effects may include skin thinning, local irritation, and systemic effects with prolonged use. Proper dosage and administration are crucial to minimize adverse effects and maximize therapeutic benefits.
Formula:C23H32O6
InChI:InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
InChI key:InChIKey=ALEXXDVDDISNDU-JZYPGELDSA-N
SMILES:C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]
Synonyms:
  • (11β)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
  • 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
  • 17-Hydroxycorticosterone 21-acetate
  • 17α-Hydroxycorticosterone acetate
  • 21-Acetate d'hydrocortisone
  • 21-Acetato De Hidrocortisona
  • 21-Acetoxy-11β,17-dihydroxypregn-4-en-3,20-dione
  • 21-Acetoxy-11β,17-dihydroxypregn-4-ene-3,20-dione
  • 21-Acetoxy-11β,17α-dihydroxypregn-4-ene-3,20-dione
  • 4-Pregnene-11β,17,21-triol-3,20-dione 21-acetate
  • See more synonyms
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