CAS 50-23-7

Cortisol

Description:

Cortisol, with the CAS number 50-23-7, is a steroid hormone produced by the adrenal cortex in response to stress and low blood glucose levels. It plays a crucial role in various physiological processes, including metabolism, immune response regulation, and the maintenance of homeostasis. Cortisol is classified as a glucocorticoid, which means it influences glucose metabolism and has anti-inflammatory effects. Its chemical formula is C21H30O5, and it has a complex structure characterized by four fused carbon rings typical of steroid compounds. Cortisol is soluble in organic solvents but has limited solubility in water. It is involved in the body's fight-or-flight response, helping to mobilize energy stores and modulate immune function. Dysregulation of cortisol levels can lead to various health issues, including Cushing's syndrome, characterized by excessive cortisol, or Addison's disease, marked by insufficient production. Due to its significant biological effects, cortisol is also used therapeutically in various medical conditions, particularly for its anti-inflammatory and immunosuppressive properties.

Formula: C₂₁H₃₀O₅

InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=JYGXADMDTFJGBT-VWUMJDOOSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]

Synonyms:

• (11Beta)-11,17,21-Trihydroxypregn-4-Ene-3,20-Dione
• (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
• 11,17,21-Trihydroxypregn-4-Ene-3,20-Dione
• 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
• 11,17a,21-Trihydroxy-4-pragnene-3,20-dione
• 11-Beta,17-Alpha,21-Trihydroxypregn-4-Ene-3,20-Dione
• 11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione
• 11β,17,21-Trihydroxypregn-4-ene-3,20-dione
• 11β,17,21-Trihydroxyprogesterone
• 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
• 11β-Hydroxycortisone
• 17-Hydroxycorticosterone
• 17α-Hydroxycorticosterone
• 4-Pregnene-11β,17α,21-triol-3,20-dione
• Acticort
• Ala-Cort
• Alkindi
• Anflam
• Cetacort
• Cobadex
• Cort-Dome
• Cortanal
• Cortef
• Cortenema
• Corticreme
• Cortifan
• Cortiment
• Cortisol
• Cortispray
• Cortonema
• Cortril
• Dermacort
• Dermocortal
• Dermolate
• Dihydrocostisone
• Dioderm
• Domolene-HC
• DuoCort
• Efcorbin
• Efcortelan
• Eldecort
• Evacort
• Ficortril
• Genacort
• HC
• Heb-Cort
• Hidro-Colisona
• Hidrocortisona
• Hycort
• Hycortol
• Hycortole
• Hydracort
• Hydrasson
• Hydro-Adreson
• Hydrocort
• Hydrocortal
• Hydrocorticosterone
• Hydrocortin
• Hydrocortison
• Hydrocortisyl
• Hydrocortone
• Hydroskin
• Hytone
• Incortin-H
• Infacort
• Medicort
• Mildison
• Nutracort
• Optef
• Otosone-F
• Penecort
• Permicort
• Plenadren
• Sanatison
• Scalpicin
• Signef
• Synacort
• Tarcortin
• Texacort
• Timocort
• Topicort
• Traumaide
• Zenoxone
• Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11β)-
• Hydrocortisone Base
• NSC 10483
• Anti-inflammatory hormone
• HYDROCORTISONE MICRONIZED

Hydrocortisone

CAS: 50-23-7

Formula: C₂₁H₃₀O₅

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 362.47

Ref: 3B-H0533

Hydrocortisone, 98%

CAS: 50-23-7

Cortisol, steroid hormone is released in response to stress and a low level of blood glucocorticoids. Its primary functions is to increase blood sugar through gluconeogenesis, suppress the immune system, and aid in fat, protein and carbohydrate metabolism. This Thermo Scientific Chemicals brand prod

Formula: C₂₁H₃₀O₅

Purity: 98%

Color and Shape: Powder, White

Molecular weight: 362.47

Ref: 02-A16292

Cortisol, 1mg/ml in Methanol

CAS: 50-23-7

Color and Shape: Single Solution

Ref: LP-COR-1630-1LM

Hydrocortisone (Cortisol)

CAS: 50-23-7

Color and Shape: Neat

Ref: 61-FOR0185.00

Cortisol

CAS: 50-23-7

Color and Shape: Neat

Ref: LP-COR-1630-10

Hydrocortisone

CAS: 50-23-7

Hydrocortisone

Formula: C₂₁H₃₀O₅

Purity: 99.5%

Color and Shape: White

Molecular weight: 362.20932

Ref: 47-576

HYDROCORTISONE CRS

CAS: 50-23-7

HYDROCORTISONE CRS

Ref: 41-H1300000

HYDROCORTISONE RS

CAS: 50-23-7

HYDROCORTISONE RS

Formula: C₂₁H₃₀O₅

Color and Shape: Powder

Molecular weight: 362.4599

Ref: 41-ICRS0325

HYDROCORTISONE FOR PEAK IDENTIFICATION CRS

CAS: 50-23-7

HYDROCORTISONE FOR PEAK IDENTIFICATION CRS

Formula: C₂₁H₃₀O₅

Color and Shape: Powder

Molecular weight: 362.4599

Ref: 41-Y0001092

Hydrocortisone

CAS: 50-23-7

Hydrocortisone is a synthetic glucocorticoid that aids in metabolism, immunity, and inflammation control.

Formula: C₂₁H₃₀O₅

Purity: 98.4% - 99.95%

Color and Shape: Plates From Alc Or Iso-Propyl Alc Solid

Molecular weight: 362.46

Ref: TM-T1614

Hydrocortisone (Hydrocortisone Acetate EP Impurity A, Cortisol)

CAS: 50-23-7

Formula: C₂₁H₃₀O₅

Molecular weight: 362.47

Ref: 4Z-H-103034

Hydrocortisone

CAS: 50-23-7

Formula: C₂₁H₃₀O₅

Purity: (UV) 98.0 - 102.0 % (dried substance)

Color and Shape: White to almost white crystalline powder

Molecular weight: 362.47

Ref: 7W-GP8860

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Controlled Product

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Color and Shape: Mixture

Ref: 04-A50000094ME

Hydrocortisone (Cortisol)

CAS: 50-23-7

Color and Shape: Neat

Ref: 86-MM0185.00

Hydrocortisone

Controlled Product

CAS: 50-23-7

Formula: C₂₁H₃₀O₅

Color and Shape: Neat

Molecular weight: 362.46

Ref: 04-C14224000

Hydrocortisone RS

CAS: 50-23-7

Color and Shape: White To Off-White Solid Crystalline Powder

Ref: 2K-1120000021

Hydrocortisone(Cortisol)

Controlled Product

CAS: 50-23-7

Impurity HYDROCORTISONE ACETATE EP IMPURITY A
Applications Cortisol, or Hydrocortisone, a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References 1. Vigore, L., et al.: Cancer Biol Ther. 2014 Jun 1;15(6):699-7062. Puurunen, J. et al.: J. Clin. Endocrinol. Metab. 2009 Jun;94(6):1973-8.3. Baltzegar, D. et al.: J Endocrinol. 2013 Nov 28;220(1):61-72.

Formula: C₂₁H₃₀O₅

Color and Shape: Neat

Molecular weight: 362.46

Ref: TR-H714615

Hydrocortisone-2,2,4,6,6,21,21-d7 (d6 Major)(Cortisol)

Controlled Product

CAS: 50-23-7

Formula: C₂₁D₇H₂₃O₅

Color and Shape: Neat

Molecular weight: 369.5

Ref: TR-H714617

Hydrocortisone

Controlled Product

CAS: 50-23-7

Hydrocortisone is a hormone that belongs to the glucocorticoid class. It is used in the treatment of various diseases, such as rheumatoid arthritis, ulcerative colitis, lupus erythematosus, and others. Hydrocortisone has been shown to inhibit cell lysis by decreasing the activity of some enzymes responsible for this process. In addition, hydrocortisone can also bind to specific receptors in the brain and regulate neurotransmitter release. Hydrocortisone has been shown to be effective against infectious diseases such as sepsis and pneumonia. However, it may cause side effects such as weight gain or mood swings when taken for a long period of time.

Formula: C₂₁H₃₀O₅

Purity: Min. 97.0 Area-%

Color and Shape: White Powder

Molecular weight: 362.46 g/mol

Ref: 3D-FH16250

Hydrocortisone pure, 97%

CAS: 50-23-7

Formula: C₂₁H₃₀O

Purity: min. 97%

Color and Shape: White to off-white, Crystalline powder, Clear, Colourless

Molecular weight: 362.47

Ref: SR-13542