CAS 51022-69-6: Amcinonide

Description: Amcinonide is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties in dermatological applications. It is characterized by its ability to reduce inflammation, itching, and redness associated with various skin conditions, such as eczema and psoriasis. Amcinonide functions by inhibiting the release of inflammatory mediators and modulating immune responses. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its chemical structure features a steroid backbone, which is common among corticosteroids, contributing to its efficacy in managing skin disorders. While generally well-tolerated, potential side effects may include skin irritation, atrophy, or systemic effects with prolonged use. As with any corticosteroid, it is important to use Amcinonide under medical supervision to mitigate risks and ensure appropriate application for specific conditions.

Formula: C₂₈H₃₅FO₇

InChI: InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1

InChI key: InChIKey=ILKJAFIWWBXGDU-MOGDOJJUSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC5OC6(OC5(C(=O)COC(=O)C)C4(C)CC(O)C32F)CCCC6)C

Synonyms:

• (11β,16α)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
• 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate
• 19alpha-Fluor-11beta,21-dihydroxy-16alpha,17alpha-(tetramethylen)methylendioxy-1,4-pregnadien-3,20-dion 21-acetat
• 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
• 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
• 2-[(4b'R,5'S,6b'S,9a'R,10a'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
• 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone, 21-acetate
• Amciderm
• Amcinonid
• Amcinonide [USAN:INN:BAN:JAN]
• Amcinonido
• Amcinonido [INN-Spanish]
• Amcinonidum
• Amcinonidum [INN-Latin]
• Cl 34699
• Cyclocort
• Penticort
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-(cyclopentylidenebis(oxy))-9-fluoro-11-hydroxy-, (11beta,16alpha)-
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11β,16α)-
• Spiro[cyclopentane-1,8′-[2H]naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole], pregna-1,4-diene-3,20-dione deriv.
• Triamcinolonacetatcyclopentanonid
• Unii-423W026Ma9
• Visderm
• Amcinonide
• Amcinonide

Amcinonide

CAS: 51022-69-6

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₈H₃₅FO₇
• Color and Shape: White Cream Crystalline Powder
• Molecular weight: 502.23668

Amcinonide

CAS: 51022-69-6

Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid …

• Formula: C₂₈H₃₅FO₇
• Purity: 98.33% - 99.62%
• Color and Shape: Solid
• Molecular weight: 502.57

Amcinonide

CAS: 51022-69-6

• Purity: ≥98%
• Molecular weight: 502.57g/mol

Amcinonide

CAS: 51022-69-6

• Formula: C₂₈H₃₅FO₇
• Purity: >95.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 502.58

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

CAS: 105102-22-5 1177-87-3 124-94-7 13609-67-1 14484-47-0 1524-88-5 2135-17-3 2152-44-5 25122-46-7 25122-57-0 3093-35-4 33564-31-7 356-12-7 378-44-9 3801-06-7 3870-07-3 426-13-1 4419-39-0 50-02-2 50-03-3 50-04-4 50-23-7 50-24-8 51022-69-651333-22-3 514-36-3 53-06-5 53-36-1 5534-09-8 5593-20-4 57524-89-7 66734-13-2 67-78-7 73771-04-7 76-25-5 80474-14-2 83-43-2 987-24-6

• Color and Shape: Mixture

Amcinonide

CAS: 51022-69-6

• Formula: C₂₈H₃₅FO₇
• Color and Shape: Neat
• Molecular weight: 502.57

Amcinonide

CAS: 51022-69-6

• Formula: C₂₈H₃₅FO₇
• Color and Shape: Neat
• Molecular weight: 502.57

Amcinonide

CAS: 51022-69-6

Applications Glucocorticoid. References Woodford, R., et al.: Curr. Ther. Res., 26, 301 (1979),

• Formula: C₂₈H₃₅FO₇
• Color and Shape: Off-White
• Molecular weight: 502.57

Amcinonide-d4

CAS: 51022-69-6

Applications Labelled Amcinonide (A576150). Glucocorticoid. References Woodford, R., et al.: Curr. Ther. Res., 26, 301 …

• Formula: C₂₈H₃₁D₄FO₇
• Color and Shape: Neat
• Molecular weight: 506.6

Amcinonide

CAS: 51022-69-6

Amcinonide is a synthetic corticosteroid that has been found to be biocompatible. It is used …

• Formula: C₂₈H₃₅FO₇
• Purity: Min. 95%
• Molecular weight: 502.57 g/mol