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CAS 51022-69-6

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Amcinonide

Description:
Amcinonide is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties in dermatological applications. It is characterized by its ability to reduce inflammation, itching, and redness associated with various skin conditions, such as eczema and psoriasis. Amcinonide functions by inhibiting the release of inflammatory mediators and modulating immune responses. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its chemical structure features a steroid backbone, which is common among corticosteroids, contributing to its efficacy in managing skin disorders. While generally well-tolerated, potential side effects may include skin irritation, atrophy, or systemic effects with prolonged use. As with any corticosteroid, it is important to use Amcinonide under medical supervision to mitigate risks and ensure appropriate application for specific conditions.
Formula:C28H35FO7
InChI:InChI=1/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19?,20?,21-,23+,24-,25-,27-,28+/m0/s1
InChI key:InChIKey=ILKJAFIWWBXGDU-MOGDOJJUSA-N
SMILES:C(COC(C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC4(O2)CCCC4)[H])([C@]5([C@](F)([C@@H](O)C3)[C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H]
Synonyms:
  • (11β,16α)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
  • 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate
  • 19alpha-Fluor-11beta,21-dihydroxy-16alpha,17alpha-(tetramethylen)methylendioxy-1,4-pregnadien-3,20-dion 21-acetat
  • 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
  • 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
  • 2-[(4b'R,5'S,6b'S,9a'R,10a'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate
  • 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone, 21-acetate
  • Amciderm
  • Amcinonid
  • Amcinonide [USAN:INN:BAN:JAN]
  • See more synonyms
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