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CAS 53-06-5

:

Cortisone

Description:
Cortisone, with the CAS number 53-06-5, is a steroid hormone that belongs to the class of glucocorticoids. It is produced naturally in the adrenal cortex and plays a crucial role in the regulation of metabolism, immune response, and stress response. Cortisone is characterized by its anti-inflammatory and immunosuppressive properties, making it valuable in medical treatments for conditions such as arthritis, allergies, and autoimmune disorders. Chemically, cortisone is a derivative of cortisol, differing primarily in its ketone structure at the C11 position. It has a molecular formula of C21H28O5 and a molecular weight of approximately 360.45 g/mol. Cortisone is typically administered in its acetate form for therapeutic purposes, enhancing its solubility and bioavailability. Its pharmacological effects are mediated through the binding to glucocorticoid receptors, influencing gene expression and cellular activity. While effective in treating various conditions, cortisone can also have side effects, particularly with long-term use, including potential impacts on metabolism, bone density, and immune function.
Formula:C21H28O5
InChI:InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=MFYSYFVPBJMHGN-ZPOLXVRWSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(C(=O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Synonyms:
  • (8Xi,9Xi,14Xi)-17,21-Dihydroxypregn-4-Ene-3,11,20-Trione
  • 11-Dehydro-17-hydroxycorticosterone
  • 17,21-Dihydroxypregn-4-Ene-3,11,20-Trione
  • 17-Alpha,21-Dihydroxypregn-4-Ene-3,11,20-Trione
  • 17-Hydroxy-11-dehydrocorticosterone
  • 17α,21-Dihydroxy-4-pregnene-3,11,20-trione
  • 17α,21β-Dihydroxy-4-pregnene-3,11,20-trione
  • 17α-Hydroxy-11-dehydrocorticosterone
  • Adrenalex
  • Compound E
  • See more synonyms
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