CAS 53-06-5: Cortisone

Description:Cortisone, with the CAS number 53-06-5, is a steroid hormone that belongs to the class of glucocorticoids. It is produced naturally in the adrenal cortex and plays a crucial role in the regulation of metabolism, immune response, and stress response. Cortisone is characterized by its anti-inflammatory and immunosuppressive properties, making it valuable in medical treatments for conditions such as arthritis, allergies, and autoimmune disorders. Chemically, cortisone is a derivative of cortisol, differing primarily in its ketone structure at the C11 position. It has a molecular formula of C21H28O5 and a molecular weight of approximately 360.45 g/mol. Cortisone is typically administered in its acetate form for therapeutic purposes, enhancing its solubility and bioavailability. Its pharmacological effects are mediated through the binding to glucocorticoid receptors, influencing gene expression and cellular activity. While effective in treating various conditions, cortisone can also have side effects, particularly with long-term use, including potential impacts on metabolism, bone density, and immune function.

Formula:C₂₁H₂₈O₅

InChI:InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key:InChIKey=MFYSYFVPBJMHGN-ZPOLXVRWSA-N

SMILES:O=C1C=C2CCC3C(C(=O)CC4(C)C3CCC4(O)C(=O)CO)C2(C)CC1

Synonyms:
(8Xi,9Xi,14Xi)-17,21-Dihydroxypregn-4-Ene-3,11,20-Trione
11-Dehydro-17-hydroxycorticosterone
17,21-Dihydroxypregn-4-Ene-3,11,20-Trione
17-Alpha,21-Dihydroxypregn-4-Ene-3,11,20-Trione
17-Hydroxy-11-dehydrocorticosterone
17α,21-Dihydroxy-4-pregnene-3,11,20-trione
17α,21β-Dihydroxy-4-pregnene-3,11,20-trione
17α-Hydroxy-11-dehydrocorticosterone
Adrenalex
Compound E
See more synonyms
Cortisate
Cortison
Cortisona
Cortivite
Cortogen
Cortone
KE
Kendall's compound E
Nsc 9703
Pregn-4-en-17α,21-diol-3,11,20-trione
Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-
Reichstein's substance Fa
Wintersteiner's compound F
Δ4-Pregnene-17α,21-diol-3,11,20-trione
Δ<sup>4</sup>-Pregnene-17α,21-diol-3,11,20-trione
Cortisone
Compound E (cortisone)

Found 11 products.

Product data	Purity	Price range	Estimated delivery
Cortisone REF: 3B-C1317CAS: 53-06-5	>97.0%(HPLC)	45.00 €	Mon 21 Apr 25
Cortisone REF: TM-T2884CAS: 53-06-5	95.48% - 99.5%	47.00 €~94.00 €	Mon 28 Apr 25
Cortisone-d5 REF: 4Z-C-2787CAS: 53-06-5	- - -	1,554.00 €~12,686.00 €	Tue 29 Apr 25
Hydrocortisone Impurity 64 Disodium Salt REF: 4Z-C-27153CAS: 2687960-86-5 53-06-5	- - -	1,101.00 €~8,997.00 €	Tue 29 Apr 25
Cortisone (Hydrocortisone EP Impurity B) REF: 4Z-C-2730CAS: 53-06-5	- - -	232.00 €~1,672.00 €	Tue 29 Apr 25
GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol REF: 04-A50000094MECAS: 105102-22-5 1177-87-3 124-94-7 13609-67-1 14484-47-0 1524-88-5 2135-17-3 2152-44-5 25122-46-7 25122-57-0 3093-35-4 33564-31-7 356-12-7 378-44-9 3801-06-7 3870-07-3 426-13-1 4419-39-0 50-02-2 50-03-3 50-04-4 50-23-7 50-24-8 51022-69-6 51333-22-3 514-36-3 53-06-5 53-36-1 5534-09-8 5593-20-4 57524-89-7 66734-13-2 67-78-7 73771-04-7 76-25-5 80474-14-2 83-43-2 987-24-6	- - -	To inquire	Tue 29 Apr 25
Cortisone REF: 7W-GP7495CAS: 53-06-5	≥ 98.0%	75.00 €~156.00 €	Mon 05 May 25
Cortisone-D8 (Major) REF: TR-C696502CAS: 53-06-5	- - -	229.00 €~2,287.00 €	Tue 06 May 25
Cortisone REF: 10-F787616CAS: 53-06-5	97%	To inquire	Tue 06 May 25
17a,21-Dihydroxypregn-4-ene-3,11,20-trione REF: 10-F374672CAS: 53-06-5	97.0%	To inquire	Tue 06 May 25
Cortisone REF: 3D-FC20558CAS: 53-06-5	Min. 97 Area-%	143.00 €~2,307.00 €	Wed 07 May 25