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CAS 57524-89-7

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Hydrocortisone valerate

Description:
Hydrocortisone valerate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema, dermatitis, and psoriasis. The substance is a derivative of hydrocortisone, modified by the addition of a valerate ester, which enhances its potency and skin penetration. Hydrocortisone valerate exhibits characteristics typical of corticosteroids, such as the ability to reduce inflammation, suppress immune responses, and promote vasoconstriction. It is generally formulated as a topical cream, ointment, or lotion, allowing for localized treatment with minimal systemic absorption. The compound is known for its relatively low side effect profile when used appropriately, although prolonged use can lead to skin atrophy or other local adverse effects. As with all corticosteroids, it is important to follow dosing guidelines to minimize potential risks. Hydrocortisone valerate is classified under the CAS number 57524-89-7, which is used for regulatory and identification purposes in chemical databases.
Formula:C26H38O6
InChI:InChI=1S/C26H38O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h13,18-20,23,27,29H,4-12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1
InChI key:InChIKey=FZCHYNWYXKICIO-FZNHGJLXSA-N
SMILES:O(C(CCCC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])[H]
Synonyms:
  • (11Beta)-11,21-Dihydroxy-3,20-Dioxopregn-4-En-17-Yl Pentanoate
  • (11β)-11,21-Dihydroxy-17-[(1-oxopentyl)oxy]pregn-4-ene-3,20-dione
  • (8Xi,9Xi,10Xi,13Xi,14Xi)-11,21-Dihydroxy-3,20-Dioxopregn-4-En-17-Yl Pentanoate
  • 11β,21-Dihydroxy-17α-valeryloxy-4-pregnene-3,20-dione
  • Cortisol 17-Valerate
  • HydroVal
  • Hydrocortisone 17-Valerate
  • Hydrocortisone pentanoate
  • Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-, (11β)-
  • Westcort
  • Hydrocortisone valerate
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