CAS 73771-04-7
:Prednicarbate
Description:
Prednicarbate is a synthetic corticosteroid primarily used in dermatology for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and psoriasis. Prednicarbate functions by inhibiting the release of inflammatory mediators and modulating immune responses. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its chemical structure features a steroid backbone, which is essential for its biological activity. Prednicarbate is known for its relatively low potency compared to other corticosteroids, making it suitable for sensitive skin areas. Additionally, it has a favorable safety profile, with a lower risk of side effects such as skin atrophy when used as directed. As with any corticosteroid, it is important to follow usage guidelines to minimize potential adverse effects and ensure effective treatment outcomes.
Formula:C27H36O8
InChI:InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
InChI key:InChIKey=FNPXMHRZILFCKX-KAJVQRHHSA-N
SMILES:C(COC(CC)=O)(=O)[C@]1(OC(OCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]
Synonyms:- (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- Brd-K46137903
- Dermatop
- EsCort
- Hoe 777
- Prednicarbat
- Prednicarbate
- Prednicarbato
- Prednisolone 17-(ethyl carbonate) 21-propionate
- Prednitop
- Regenit
- S 77-0777
- 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propanoate
- (11beta)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propanoate
- 73771-04-7
- See more synonyms
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Found 14 products.
PREDNICARBATE FOR PEAK IDENTIFICATION CRS
CAS:<p>PREDNICARBATE FOR PEAK IDENTIFICATION CRS</p>Color and Shape:Added AddedPREDNICARBATE FOR SYSTEM SUITABILITY A CRS
CAS:<p>PREDNICARBATE FOR SYSTEM SUITABILITY A CRS</p>Formula:C27H36O8Color and Shape:AddedMolecular weight:488.5699PREDNICARBATE CRS
CAS:<p>PREDNICARBATE CRS</p>Formula:C27H36O8Color and Shape:AddedMolecular weight:488.5699Prednicarbate
CAS:<p>Adrenal cortical hormones and their derivatives nesoi</p>Formula:C27H36O8Color and Shape:White Off-White PowderMolecular weight:488.24102Prednicarbate
CAS:<p>Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.</p>Formula:C27H36O8Purity:99.88%Color and Shape:SolidMolecular weight:488.57Prednicarbate
CAS:Formula:C27H36O8Purity:≥ 98.0%Color and Shape:White crystalline powderMolecular weight:488.57GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Controlled Product- 105102-22-5
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- 356-12-7
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- 50-02-2
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- 50-04-4
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- 51022-69-6
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- 514-36-3
- 53-06-5
- 5534-09-8
- 5593-20-4
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- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Color and Shape:MixturePrednicarbate
CAS:Controlled Product<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formula:C27H36O8Color and Shape:Off-WhiteMolecular weight:488.57Prednicarbate - EP
CAS:Controlled Product<p>Prednicarbate is an alopecia areata drug that is a corticosteroid. Prednicarbate is a prodrug, which means it needs to be converted by the liver into prednisolone before it can take effect. Prednicarbate has been shown to reduce the activity of disease-causing cells and to have anti-inflammatory properties. It does this by binding to glucocorticoid receptors on the surface of cells and inhibiting the production of inflammatory substances. Prednicarbate has been shown to have anti-inflammatory effects in animal models for inflammatory skin diseases, such as glomerular filtration rate and receptor binding. Prednicarbate may also suppress epidermal growth factor, leading to less cell proliferation in hair follicles.</p>Formula:C27H36O8Purity:97.0 To 102.0 Area-%Color and Shape:White PowderMolecular weight:488.57 g/molPrednicarbate,USP
CAS:Controlled Product<p>Prednicarbate, USP is a drug that belongs to the class of corticosteroids. It has been used to treat alopecia areata as well as inflammatory skin diseases such as psoriasis, atopic dermatitis, and seborrheic dermatitis. Prednicarbate, USP functions by inhibiting the production of prostaglandins in the skin. This action reduces inflammation and protects against damage to the epidermal barrier. Prednicarbate, USP has also been shown to inhibit phospholipase A2 activity in vitro and has a favorable chemical stability profile. The drug is metabolized through glucuronidation in humans and animals. Prednicarbate is highly lipophilic with a high affinity for fatty acids which may lead to its accumulation in adipose tissue. The drug also binds to receptors on inflammatory cells which may contribute to its anti-inflammatory properties.</p>Formula:C27H36O8Purity:Min. 95%Molecular weight:488.57 g/mol










