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CAS 73771-04-7

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Prednicarbate

Description:
Prednicarbate is a synthetic corticosteroid primarily used in dermatology for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and psoriasis. Prednicarbate functions by inhibiting the release of inflammatory mediators and modulating immune responses. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its chemical structure features a steroid backbone, which is essential for its biological activity. Prednicarbate is known for its relatively low potency compared to other corticosteroids, making it suitable for sensitive skin areas. Additionally, it has a favorable safety profile, with a lower risk of side effects such as skin atrophy when used as directed. As with any corticosteroid, it is important to follow usage guidelines to minimize potential adverse effects and ensure effective treatment outcomes.
Formula:C27H36O8
InChI:InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
InChI key:InChIKey=FNPXMHRZILFCKX-KAJVQRHHSA-N
SMILES:C(COC(CC)=O)(=O)[C@]1(OC(OCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]
Synonyms:
  • (11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • Brd-K46137903
  • Dermatop
  • EsCort
  • Hoe 777
  • Prednicarbat
  • Prednicarbate
  • Prednicarbato
  • Prednisolone 17-(ethyl carbonate) 21-propionate
  • Prednitop
  • See more synonyms
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Found 14 products.
  • PREDNICARBATE FOR PEAK IDENTIFICATION CRS

    CAS:
    <p>PREDNICARBATE FOR PEAK IDENTIFICATION CRS</p>
    Color and Shape:Added Added

    Ref: 41-Y0002231

    15mg
    115.00€
  • PREDNICARBATE FOR SYSTEM SUITABILITY A CRS

    CAS:
    <p>PREDNICARBATE FOR SYSTEM SUITABILITY A CRS</p>
    Formula:C27H36O8
    Color and Shape:Added
    Molecular weight:488.5699

    Ref: 41-Y0001630

    10mg
    115.00€
  • PREDNICARBATE CRS

    CAS:
    <p>PREDNICARBATE CRS</p>
    Formula:C27H36O8
    Color and Shape:Added
    Molecular weight:488.5699

    Ref: 41-P2698000

    110mg
    115.00€
  • Prednicarbate

    CAS:
    <p>Adrenal cortical hormones and their derivatives nesoi</p>
    Formula:C27H36O8
    Color and Shape:White Off-White Powder
    Molecular weight:488.24102
  • Prednicarbate

    CAS:
    <p>Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.</p>
    Formula:C27H36O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:488.57
  • Prednicarbate

    CAS:
    Formula:C27H36O8
    Purity:≥ 98.0%
    Color and Shape:White crystalline powder
    Molecular weight:488.57

    Ref: 7W-GP5901

    ne
    To inquire
  • Prednicarbate

    CAS:
    Formula:C27H36O8
    Color and Shape:White To Off-White Solid
    Molecular weight:488.58

    Ref: 4Z-P-821

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Prednicarbate

    CAS:
    <p>Prednicarbate</p>
    Purity:≥98%
    Molecular weight:488.57g/mol

    Ref: 54-BUP06581

    10mg
    50.00€
    25mg
    77.00€
    50mg
    130.00€
  • Prednicarbate

    Controlled Product
    CAS:
    Formula:C27H36O8
    Color and Shape:Neat
    Molecular weight:488.57

    Ref: 04-C16286450

    100mg
    161.00€
  • Ref: 04-A50000094ME

    1500µl
    To inquire
  • Prednicarbate

    Controlled Product
    CAS:
    Formula:C27H36O8
    Color and Shape:Off-White
    Molecular weight:488.57

    Ref: 86-MM3382.00

    250mg
    305.00€
  • Prednicarbate

    Controlled Product
    CAS:
    <p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>
    Formula:C27H36O8
    Color and Shape:Off-White
    Molecular weight:488.57

    Ref: TR-P703700

    1g
    1,462.00€
    100mg
    263.00€
    250mg
    516.00€
  • Prednicarbate - EP

    Controlled Product
    CAS:
    <p>Prednicarbate is an alopecia areata drug that is a corticosteroid. Prednicarbate is a prodrug, which means it needs to be converted by the liver into prednisolone before it can take effect. Prednicarbate has been shown to reduce the activity of disease-causing cells and to have anti-inflammatory properties. It does this by binding to glucocorticoid receptors on the surface of cells and inhibiting the production of inflammatory substances. Prednicarbate has been shown to have anti-inflammatory effects in animal models for inflammatory skin diseases, such as glomerular filtration rate and receptor binding. Prednicarbate may also suppress epidermal growth factor, leading to less cell proliferation in hair follicles.</p>
    Formula:C27H36O8
    Purity:97.0 To 102.0 Area-%
    Color and Shape:White Powder
    Molecular weight:488.57 g/mol

    Ref: 3D-FP172966

    1g
    1,678.00€
    50mg
    336.00€
    100mg
    489.00€
    250mg
    718.00€
    500mg
    1,090.00€
  • Prednicarbate,USP

    Controlled Product
    CAS:
    <p>Prednicarbate, USP is a drug that belongs to the class of corticosteroids. It has been used to treat alopecia areata as well as inflammatory skin diseases such as psoriasis, atopic dermatitis, and seborrheic dermatitis. Prednicarbate, USP functions by inhibiting the production of prostaglandins in the skin. This action reduces inflammation and protects against damage to the epidermal barrier. Prednicarbate, USP has also been shown to inhibit phospholipase A2 activity in vitro and has a favorable chemical stability profile. The drug is metabolized through glucuronidation in humans and animals. Prednicarbate is highly lipophilic with a high affinity for fatty acids which may lead to its accumulation in adipose tissue. The drug also binds to receptors on inflammatory cells which may contribute to its anti-inflammatory properties.</p>
    Formula:C27H36O8
    Purity:Min. 95%
    Molecular weight:488.57 g/mol

    Ref: 3D-FP179099

    10mg
    303.00€
    25mg
    473.00€
    50mg
    632.00€
    100mg
    931.00€
    250mg
    1,502.00€