CAS 76-25-5: Triamcinolone acetonide

Description: Triamcinolone acetonide is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in various medical applications. It is characterized by its ability to inhibit the release of inflammatory mediators, making it effective in treating conditions such as allergies, asthma, and skin disorders. The substance appears as a white to off-white crystalline powder and is relatively insoluble in water but soluble in organic solvents like ethanol and acetone. Its chemical structure features a steroid backbone with a 16α-methyl group and a 21-acetate group, which contribute to its potency and duration of action. Triamcinolone acetonide is often administered via topical, intranasal, or injectable routes, depending on the condition being treated. While generally well-tolerated, potential side effects may include local irritation, hormonal imbalances, and systemic effects with prolonged use. As with all corticosteroids, careful consideration of dosage and duration of therapy is essential to minimize adverse effects.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI key: InChIKey=YNDXUCZADRHECN-JNQJZLCISA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC5OC(OC5(C(=O)CO)C4(C)CC(O)C32F)(C)C)C

Synonyms:

• (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• (4aS,4bR,5S,6aS,6bS,9aR)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
• 4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
• 9-Alpha-Fluoro-11-Beta,21-Dihydroxy-16-Alpha,17-Alpha-Isopropylidenedioxypregna-1,4-Diene-3,20-Dione
• 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide
• 9-Fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
• 9-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
• 9-Α-Fluoro-11-Β,21-Dihidroxi-16-Α-17-Α-Isopropilidendioxipregna-1,4-Dieno-3,20-Diona
• 9-Α-Fluoro-11-Β,21-Dihydroxy-16-Α,17-Α-Isopropylidenedioxypregna-1,4-Diene-3,20-Dione
• 9-α-Fluor-11-β,21-dihydroxy-16-α,17-α-isopropylidendioxypregna-1,4-dien-3,20-dion
• 9a-Fluoro-11b,16a,17a,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide
• 9a-Fluoro-16a-hydroxyprednisolone 16a,17a-acetonide
• 9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
• 9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione
• Adcortyl
• Adcortyl A
• Aftach
• Aristicort
• Aristocort A
• Aristocort acetonide
• Aristoderm
• Azmacort
• Berlicort
• Delphicort
• Extracort
• Ftorocort
• I-Vation
• Kenacort 40
• Kenacort 80
• Kenacort A
• Kenacort A 40
• Kenalog
• Kenalog 10
• Kenalog 40
• Ledercort Cream
• Lichtena
• MaQuaid
• Nasacort
• Nsc 21916
• Omcilon A
• Paralen
• Pol'kortolon
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
• Queyanshusong A
• Respicort
• Rheudenolone
• Rineton
• Solodelf
• Tac 3
• Tac 40
• Tamceton
• Tramacin
• Tri-Nasal
• Triacet
• Triakort
• Triam
• Triamcinolone 16,17-acetonide
• Triamcinolone 16α,17α-acetonide
• Triamcinolone Acetonide BP98
• Triamcort-Depot
• Triamhexal
• Triamonide 40
• Trianopollon
• Tricinolon
• Triesence
• Trivaris
• Trymex
• Valon A 10
• Vetalog
• Vetazine
• Volon A
• Volonimat

Triamcinolone Acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Purity: >98.0%(E)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 434.50

Triamcinolone acetonide, 98+%

CAS: 76-25-5

Triamcinolone acetonide suppresses allergic, inflammatory, and immune responses. Intravitreal administration of triamcinolone acetonide is used …

• Formula: C₂₄H₃₁FO₆
• Purity: 98+%
• Molecular weight: 434.50

Triamcinolone acetonide for system suitability CRS

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Molecular weight: 434.4977

Triamcinolone acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Purity: 98.6%
• Color and Shape: White Solid
• Molecular weight: 434.21047

Triamcinolone acetonide CRS

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Crystalline Powder. White. Powder.
• Molecular weight: 434.4977

Triamcinolone Acetonide

CAS: 76-25-5

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White Powder
• Molecular weight: 434.21047

(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 434.4977

Triamcinolone acetonide

CAS: 76-25-5

Triamcinolone acetonide (Azmacort) is a Corticosteroid.

• Formula: C₂₄H₃₁FO₆
• Purity: 99.61% - 99.91%
• Color and Shape: White To Off-White Crystalline Powder
• Molecular weight: 434.5

Triamcinolone Acetonide-d6

CAS: 76-25-5

• Formula: C₂₄H₂₅D₆FO₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 440.54

Triamcinolone Acetonide-d7

CAS: 76-25-5

• Formula: C₂₄H₂₄D₇FO₆
• Color and Shape: Off-White Solid
• Molecular weight: 441.55

Triamcinolone Acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 434.50

Triamcinolone acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Purity: 98.0 - 102.0 % (anhydrous basis)
• Color and Shape: White or almost white crystalline powder
• Molecular weight: 434.50

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

CAS: 105102-22-5 1177-87-3 124-94-7 13609-67-1 14484-47-0 1524-88-5 2135-17-3 2152-44-5 25122-46-7 25122-57-0 3093-35-4 33564-31-7 356-12-7 378-44-9 3801-06-7 3870-07-3 426-13-1 4419-39-0 50-02-2 50-03-3 50-04-4 50-23-7 50-24-8 51022-69-6 51333-22-3 514-36-3 53-06-5 53-36-1 5534-09-8 5593-20-4 57524-89-7 66734-13-2 67-78-7 73771-04-7 76-25-580474-14-2 83-43-2 987-24-6

• Color and Shape: Mixture

Triamcinolone acetonide 100 µg/mL in Methanol

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Single Solution
• Molecular weight: 434.50

Triamcinolone Acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Neat
• Molecular weight: 434.50

Triamcinolone acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Neat
• Molecular weight: 434.50

Triamcinolone Acetonide RS

CAS: 76-25-5

• Color and Shape: White Or Almost White Solid Crystalline Solid

Triamcinolone Acetonide-d7 (major)

CAS: 352431-33-5 76-25-5

Applications Triamcinolone Acetonide-d6 is the labeled analogue of Triamcinolone Acetonide (T767165), a glucocorticoid, antiasthmatic (inhalant); …

• Formula: C₂₄H₂₄D₇FO₆
• Color and Shape: Off-White To Beige
• Molecular weight: 441.54088

Triamcinolone Acetonide

CAS: 76-25-5

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White
• Molecular weight: 434.50

Triamcinolone acetonide

CAS: 76-25-5

Glucocorticoid receptor agonist; anti-inflammatory; immunosuppressant

• Formula: C₂₄H₃₁FO₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 434.5 g/mol