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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 2121 products of "Angiogenesis"

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  • Vatalanib free base

    CAS:
    Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
    Formula:C20H15ClN4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:346.81
  • PD-089828

    CAS:
    PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).
    Formula:C18H18Cl2N6O
    Purity:97.39%
    Color and Shape:Solid
    Molecular weight:405.28
  • E-4031 dihydrochloride

    CAS:
    E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
    Formula:C21H29Cl2N3O3S
    Purity:99.31% - 99.87%
    Color and Shape:Solid
    Molecular weight:474.44
  • Avitinib

    CAS:
    Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,
    Formula:C26H26FN7O2
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:487.53
  • Tyrphostin B44, (+) enantiomer

    CAS:
    Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)
    Formula:C18H16N2O3
    Purity:97.18%
    Color and Shape:Solid
    Molecular weight:308.33
  • Mubritinib

    CAS:
    Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
    Formula:C25H23F3N4O2
    Purity:98.61% - 99.85%
    Color and Shape:Solid
    Molecular weight:468.47
  • Tyrphostin AG1296

    CAS:
    Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.
    Formula:C16H14N2O2
    Purity:99.94% - >99.99%
    Color and Shape:Solid
    Molecular weight:266.29
  • ZM323881

    CAS:
    ZM323881 is a potent and selective inhibitor of VEGFR2 with an IC 50 of less than 2 nM.
    Formula:C22H18FN3O2
    Color and Shape:Solid
    Molecular weight:375.4
  • Pantoprazole sodium

    CAS:
    Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.
    Formula:C16H14F2N3NaO4S
    Purity:96.92% - 99.81%
    Color and Shape:White To Off-White Solid
    Molecular weight:405.35
  • WS6

    CAS:
    WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
    Formula:C29H31F3N6O3
    Purity:97.65% - 99.95%
    Color and Shape:Solid
    Molecular weight:568.59
  • Quizartinib HCl

    CAS:
    Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.
    Formula:C29H34Cl2N6O4S
    Color and Shape:Solid
    Molecular weight:633.59
  • Tyrphostin A1

    CAS:
    Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .
    Formula:C11H8N2O
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:184.19
  • 7BIO

    CAS:
    <p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>
    Formula:C16H10BrN3O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:356.17
  • NS309

    CAS:
    NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.
    Formula:C8H4Cl2N2O2
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:231.04
  • Olafertinib

    CAS:
    Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.
    Formula:C29H28F2N6O2
    Purity:98.62% - 99.706%
    Color and Shape:Solid
    Molecular weight:530.57
  • Tofacitinib

    CAS:
    Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.
    Formula:C16H20N6O
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:312.37
  • CHIR-124

    CAS:
    CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
    Formula:C23H22ClN5O
    Purity:96.33% - 98.35%
    Color and Shape:Solid
    Molecular weight:419.91
  • Nintedanib esylate

    CAS:
    Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β
    Formula:C31H33N5O4·C2H6O3S
    Purity:99.43% - 99.98%
    Color and Shape:Solid
    Molecular weight:649.76
  • SB-431542

    CAS:
    SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.
    Formula:C22H16N4O3
    Purity:99.035% - >99.99%
    Color and Shape:Solid
    Molecular weight:384.39
  • Afatinib

    CAS:
    <p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>
    Formula:C24H25ClFN5O3
    Purity:98.56% - 99.9%
    Color and Shape:Off-White Solid
    Molecular weight:485.94