Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(167 products)
- Bcr-Abl(118 products)
- EGFR(581 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2384 products of "Angiogenesis"
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BO-264
CAS:BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).Formula:C18H19N5O3Purity:98.03% - 99.81%Color and Shape:SolidMolecular weight:353.38Xanthinol Nicotinate
CAS:Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increasedFormula:C13H21N5O4·C6H5NO2Purity:99.91%Color and Shape:White Crystalline PowderMolecular weight:434.45Nintedanib
CAS:Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formula:C31H33N5O4Purity:98% - 99.92%Color and Shape:SolidMolecular weight:539.62Atopaxar hydrochloride
CAS:Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.Formula:C29H39ClFN3O5Color and Shape:SolidMolecular weight:564.1SKLB1002
CAS:SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.Formula:C13H12N4O2S2Purity:98.51% - >99.99%Color and Shape:SolidMolecular weight:320.39VH-298
CAS:VH-298 blocks VHL:HIF-α interaction, stabilizes HIF-α, and triggers hypoxic response differently by inhibiting VHL post-HIF-α PHD hydroxylation.
Formula:C27H33N5O4SPurity:99.17% - >99.99%Color and Shape:SolidMolecular weight:523.65(Z)-SU4312
CAS:(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Formula:C17H16N2OPurity:99.17%Color and Shape:SolidMolecular weight:264.32Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
Formula:C18H21N5SPurity:99.63%Color and Shape:SolidMolecular weight:339.46AST5902 mesylate(2412155-74-7 free base)
CAS:AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.Formula:C28H33F3N8O5SPurity:97.04% - 99.46%Color and Shape:SolidMolecular weight:650.67Ref: TM-T8945L
1mg128.00€5mg253.00€10mg400.00€25mg662.00€50mg888.00€100mg1,243.00€500mg2,502.00€1mL*10mM (DMSO)405.00€Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg49.00€10mg74.00€25mg130.00€50mg200.00€100mg319.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)69.00€Momelotinib HCl
CAS:Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formula:C23H24Cl2N6O2Color and Shape:SolidMolecular weight:487.38CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purity:98%Color and Shape:SolidMolecular weight:428.53OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Ensartinib
CAS:Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).Formula:C26H27Cl2FN6O3Purity:99.92%Color and Shape:SolidMolecular weight:561.44Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purity:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:146.53 kDaRef: TM-T9904
1mg127.00€2mg202.00€5mg376.00€10mg560.00€25mg895.00€50mg1,216.00€100mg1,634.00€200mg2,213.00€RN486
CAS:RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).Formula:C35H35FN6O3Purity:99.38%Color and Shape:SolidMolecular weight:606.69ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formula:C24H27N7OPurity:99.53% - 99.7%Color and Shape:SolidMolecular weight:429.52Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68Ref: TM-T1995
1g592.00€5mg50.00€10mg65.00€50mg107.00€100mg127.00€200mg205.00€500mg447.00€1mL*10mM (DMSO)54.00€Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purity:98.52% - >99.99%Color and Shape:SolidMolecular weight:425.46Ref: TM-T14687
1mg56.00€5mg137.00€10mg248.00€25mg389.00€50mg575.00€100mg817.00€1mL*10mM (DMSO)149.00€PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.92%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg34.00€5mg96.00€10mg141.00€25mg289.00€50mg465.00€100mg662.00€200mg888.00€1mL*10mM (DMSO)118.00€Desmethyl Erlotinib hydrochloride
CAS:Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.Formula:C21H21N3O4·HClPurity:99.49%Color and Shape:SolidMolecular weight:415.87Ref: TM-T6619
1mg56.00€2mg79.00€5mg109.00€10mg178.00€25mg318.00€50mg479.00€100mg682.00€1mL*10mM (DMSO)120.00€SU4984
CAS:SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formula:C20H19N3O2Purity:97.20%Color and Shape:SolidMolecular weight:333.38HG-14-10-04
CAS:HG-14-10-04 is a potent and specific ALK inhibitor.Formula:C29H34ClN7OPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:532.08Ref: TM-T4015
1mg49.00€5mg92.00€10mg152.00€25mg222.00€50mg289.00€100mg409.00€200mg590.00€1mL*10mM (DMSO)111.00€JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35NVP-TAE 226
CAS:NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94Ref: TM-T1918
1mg46.00€2mg59.00€5mg96.00€10mg155.00€25mg250.00€50mg358.00€100mg537.00€1mL*10mM (DMSO)96.00€AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purity:98.02% - 99.94%Color and Shape:SolidMolecular weight:322.36Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formula:C30H33F3N8O4SPurity:99.82%Color and Shape:SolidMolecular weight:658.69Ref: TM-T7861
1mg34.00€5mg84.00€10mg126.00€25mg236.00€50mg371.00€100mg595.00€500mg1,234.00€1mL*10mM (DMSO)132.00€AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purity:99.62%Color and Shape:SolidMolecular weight:496.36Ref: TM-T4249
2mg34.00€5mg46.00€10mg62.00€25mg94.00€50mg167.00€100mg265.00€200mg385.00€1mL*10mM (DMSO)49.00€Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purity:99.4% - 99.72%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2483
1mg35.00€2mg50.00€5mg74.00€10mg120.00€25mg170.00€50mg215.00€100mg334.00€200mg421.00€500mg692.00€1mL*10mM (DMSO)74.00€SSR128129E
CAS:SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.Formula:C18H15N2O4·NaPurity:98.79% - ≥95%Color and Shape:SolidMolecular weight:346.31VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formula:C24H20Cl2FN5O2Purity:98.92% - ≥98%Color and Shape:SolidMolecular weight:500.35PF-431396
CAS:PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Formula:C22H21F3N6O3SPurity:98.83% - 99.82%Color and Shape:SolidMolecular weight:506.5Rigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formula:C21H25NO8SPurity:99.53%Color and Shape:SolidMolecular weight:451.49A-419259
CAS:A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formula:C29H34N6OPurity:99.48%Color and Shape:SolidMolecular weight:482.62MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39Ref: TM-T6886
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg245.00€50mg358.00€100mg537.00€1mL*10mM (DMSO)90.00€FGFR2-IN-3 hydrochloride
CAS:FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formula:C28H25ClFN7O2Color and Shape:SolidMolecular weight:546.0(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.24% - ≥95%Color and Shape:SolidMolecular weight:462.57Ref: TM-T6122
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg231.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)92.00€Syk Inhibitor II dihydrochloride
CAS:Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formula:C14H17Cl2F3N6OPurity:98.53%Color and Shape:SolidMolecular weight:413.22Ref: TM-T4391
1mg130.00€2mg212.00€5mg455.00€10mg647.00€25mg947.00€50mg1,264.00€100mg1,700.00€1mL*10mM (DMSO)455.00€Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurity:99.38% - >99.99%Color and Shape:SolidMolecular weight:447.51CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37BMS817378
CAS:BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).Formula:C24H18ClF2N4O7PPurity:>99.99%Color and Shape:SolidMolecular weight:578.85(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formula:C29H35ClFN7O3Purity:99.64%Color and Shape:SolidMolecular weight:584.08Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07% - 99.62%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg74.00€2mg97.00€5mg165.00€10mg274.00€25mg432.00€50mg692.00€100mg1,121.00€200mg1,539.00€1mL*10mM (DMSO)202.00€PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg44.00€5mg90.00€10mg145.00€25mg268.00€50mg439.00€100mg700.00€200mg954.00€1mL*10mM (DMSO)90.00€Vatalanib succinate
CAS:Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.Formula:C24H21ClN4O4Color and Shape:SolidMolecular weight:464.91CUDC-101
CAS:CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.Formula:C24H26N4O4Purity:95.76% - 99.17%Color and Shape:SolidMolecular weight:434.49GSK2256098
CAS:GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.Formula:C20H23ClN6O2Purity:99.46% - 99.74%Color and Shape:SolidMolecular weight:414.89Ref: TM-T2281
1mg44.00€2mg57.00€5mg84.00€10mg130.00€25mg249.00€50mg424.00€100mg625.00€500mg1,314.00€1mL*10mM (DMSO)84.00€
