Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(118 products)
- EGFR(582 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2382 products of "Angiogenesis"
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CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.24% - ≥95%Color and Shape:SolidMolecular weight:462.57Ref: TM-T6122
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg231.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)92.00€Atopaxar hydrochloride
CAS:Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.Formula:C29H39ClFN3O5Color and Shape:SolidMolecular weight:564.1Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Formula:C26H28Cl2N6O2SColor and Shape:SolidMolecular weight:559.51SKLB1002
CAS:SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.Formula:C13H12N4O2S2Purity:98.51% - >99.99%Color and Shape:SolidMolecular weight:320.39Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68Ref: TM-T1995
1g592.00€5mg50.00€10mg65.00€50mg107.00€100mg127.00€200mg205.00€500mg447.00€1mL*10mM (DMSO)54.00€Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg49.00€10mg74.00€25mg130.00€50mg200.00€100mg319.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)69.00€VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purity:99.92%Color and Shape:SolidMolecular weight:364.45Ref: TM-T2056
1mg90.00€5mg222.00€10mg333.00€25mg560.00€50mg797.00€100mg1,071.00€1mL*10mM (DMSO)224.00€HA 155
CAS:HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.Formula:C24H19BFNO5SPurity:99.88%Color and Shape:SolidMolecular weight:463.29OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purity:98.52% - >99.99%Color and Shape:SolidMolecular weight:425.46Ref: TM-T14687
1mg56.00€5mg137.00€10mg248.00€25mg389.00€50mg575.00€100mg817.00€1mL*10mM (DMSO)149.00€Ensartinib
CAS:Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).Formula:C26H27Cl2FN6O3Purity:99.92%Color and Shape:SolidMolecular weight:561.44Ensartinib hydrochloride
CAS:Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of knownFormula:C26H29Cl4FN6O3Purity:98.73%Color and Shape:SolidMolecular weight:634.36Ref: TM-T22324
1mg54.00€5mg114.00€10mg177.00€25mg356.00€50mg580.00€100mg888.00€1mL*10mM (DMSO)158.00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purity:97.07% - 99.56%Color and Shape:SolidMolecular weight:414.46Ref: TM-T1849
1mg35.00€2mg50.00€5mg77.00€10mg89.00€25mg158.00€50mg245.00€100mg385.00€200mg592.00€1mL*10mM (DMSO)84.00€TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg34.00€2mg49.00€5mg74.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€500mg1,099.00€1mL*10mM (DMSO)87.00€SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).Formula:C23H25ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:408.92Ref: TM-T4227
1mg50.00€2mg65.00€5mg107.00€10mg170.00€25mg306.00€50mg371.00€100mg553.00€1mL*10mM (DMSO)117.00€KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Formula:C30H37ClN8O4Purity:96.19%Color and Shape:SolidMolecular weight:609.12OICR-9429
CAS:OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.Formula:C29H32F3N5O3Purity:97.07% - 99.93%Color and Shape:SolidMolecular weight:555.59Ref: TM-T6916
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg177.00€50mg295.00€100mg475.00€1mL*10mM (DMSO)92.00€Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73BX-912
CAS:BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.Formula:C20H23BrN8OPurity:98.29% - 99.34%Color and Shape:SolidMolecular weight:471.35Ref: TM-T1837
1mg50.00€2mg71.00€5mg85.00€10mg137.00€25mg281.00€50mg470.00€100mg632.00€1mL*10mM (DMSO)88.00€Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purity:98.66% - 99.99%Color and Shape:SolidMolecular weight:509.34Cpd27
CAS:Cpd27 (TIE-2/VEGFR-2 kinase-IN-2) is a TIE-2 and VEGFR-2 inhibitor that inhibits RIPK1 and can be used to study glaucoma.Formula:C20H13F4N5O2Purity:98.89%Color and Shape:SolidMolecular weight:431.34Bosutinib hydrate
CAS:Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.Formula:C26H31Cl2N5O4Purity:99.87%Color and Shape:SolidMolecular weight:548.46SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurity:97.79%Color and Shape:SolidMolecular weight:413.9Donafenib
CAS:Donafenib(Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3,Formula:C21H13ClD3F3N4O3Purity:99.88%Color and Shape:SolidMolecular weight:467.84Ref: TM-T16909
1mg87.00€5mg178.00€10mg321.00€25mg532.00€50mg770.00€100mg1,035.00€1mL*10mM (DMSO)192.00€GS-829845
CAS:GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-lifeFormula:C17H19N5O2SPurity:99.93%Color and Shape:SolidMolecular weight:357.43Pulsatilla Saponin D (90%)
CAS:Controlled ProductApplications Pulsatilla Saponin D shows antiangiogenic and antitumor activity.
References Sang-Won, H. et al.: Carcinogen., 34, 2156 (2013);Formula:C47H76O17Purity:90%Color and Shape:NeatMolecular weight:913.1Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formula:C22H25FN4O2Purity:97.62%Color and Shape:SolidMolecular weight:396.46Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Osunprotafib
CAS:Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.Cost-effective and quality-assured.Formula:C17H24FN3O4SPurity:97.11% - 99.91%Color and Shape:SolidMolecular weight:385.45Anumigilimab
CAS:Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Purity:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.86 kDaTG 100801
CAS:TG 100801 is a dual inhibitor of VEGFr2 and Src family kinases and is a candidate compound for the treatment of age-related macular degeneration (AMD).Formula:C33H30ClN5O3Purity:99.28% - 99.61%Color and Shape:SolidMolecular weight:580.08Tirabrutinib
CAS:Tirabrutinib, an oral Btk inhibitor (IC50=6.8 nM), crosses the BBB and halts B cell signaling for autoimmune and hematologic studies.
Formula:C25H22N6O3Purity:99.64%Color and Shape:SolidMolecular weight:454.48N-Acryloyl Osimertinib (>85%)
CAS:Applications N-Acryloyl Osimertinib is used in the preparation of pyrimidinyl indole derivative as EGFR inhibitor for targeted therapy of cancer
References Rao, Y., et al.: Faming Zhuanli Shenqing (2016), CN 105777716 A 20160720Formula:C31H35N7O3Purity:>85%Color and Shape:Off White SolidMolecular weight:553.65PDGFR Tyrosine Kinase Inhibitor III
CAS:PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor thatFormula:C27H27N5O4Purity:99.50%Color and Shape:SoildMolecular weight:485.53CCT241161
CAS:CCT241161: oral pan-RAF inhibitor; IC50s: LCK (3 nM), CRAF (6), SRC (10), V600E-BRAF (15), BRAF (30); fights BRAF/NRAS melanomas, anti-proliferative.Formula:C28H27N7O3SPurity:99.76% - 99.77%Color and Shape:SolidMolecular weight:541.62Clopidogrel Related Compound B
CAS:Impurity Clopidogrel Impurity B; Clopidogrel USP B; Clopidogrel USP Related Compound B
Applications Clopidogrel Related Compound B (Clopidogrel Impurity B; Clopidogrel USP B; Clopidogrel USP Related Compound B) is a tetrahydrothienopyridine as inhibitor of angiogenesis.
References Maffrand, J. P., et al.: Eur. J. Med. Chem., 9, 483 (1974), Thebault, J.J., et al.: Clin. Pharmacol. Ther., 18, 485 (1975),Formula:C16H16ClNO2S·ClHColor and Shape:NeatMolecular weight:358.28Gefitinib hydrochloride
CAS:Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.Formula:C22H25Cl2FN4O3Purity:99.8%Color and Shape:SolidMolecular weight:483.36AZ 12799734
CAS:AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours.Formula:C18H18N4O3SPurity:98.23%Color and Shape:SolidMolecular weight:370.43SB-505124 hydrochloride
CAS:SB-505124 hydrochloride (SB505124 hydrochloride) is a TGF-β type I receptor (ALK4, ALK5, ALK7) inhibitor for the study of colorectal cancer.Formula:C20H22ClN3O2Purity:98.71%Color and Shape:SolidMolecular weight:371.86GSK1904529A
CAS:GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Formula:C44H47F2N9O5SPurity:98.2% - 99.76%Color and Shape:SolidMolecular weight:851.96Alpha-Eudesmol
CAS:Applications α-Eudesmol is an isomer of β-Eudesmol (E938600), a sesquiterpenoid known to induce neurite outgrowth. β-Eudesmol exhibits antiangiogenic activity.
References Obara, Y. et al.: J. Pharmacol. Exp . Ther., 30, 803 (2011); Tsuneki, H. et al.: Eur. J. Pharmacol., 512, 105 (2005);Formula:C15H26OColor and Shape:White To Off-WhiteMolecular weight:222.37Seribantumab
CAS:Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting cancer cell proliferation.Purity:>95%Color and Shape:LiquidMolecular weight:143.14 kDaItacnosertib
CAS:Itacnosertib (TP-0184) is an orally available ACRV1 (ALK-2), FLT3 and JAK2 inhibitor that inhibits the growth of tumor cells,antitumor and antileukemic.Formula:C26H28N8OPurity:99.38%Color and Shape:SolidMolecular weight:468.55Ref: TM-T39104
1mg92.00€5mg192.00€10mg313.00€25mg595.00€50mg888.00€100mg1,234.00€200mg1,665.00€1mL*10mM (DMSO)212.00€Glycerol 1-Monobutyrate (Technical Grade)
CAS:Applications Glycerol 1-Monobutyrate functions as a key regulatory molecule in angiogenic process.
References Dobson, D. E., et al.: Cell (Cambridge, MA, U. S.), 61, 223 (1990)Formula:C7H14O4Color and Shape:NeatMolecular weight:162.18Dapolsertib
CAS:Dapolsertib (SEL24-B489) is an orally active and efficient PIM and FLT3-ITD inhibitor, reducing PIM-specific substrate phosphorylation.Formula:C15H18Br2N4O2Purity:99.61%Color and Shape:SolidMolecular weight:446.14FAK activator 1
CAS:ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.Formula:C23H26F3N3O3Purity:99.19%Color and Shape:SoildMolecular weight:449.47Ref: TM-T77665
1mg94.00€5mg217.00€10mg362.00€25mg594.00€50mg952.00€100mg1,506.00€200mg1,969.00€1mL*10mM (DMSO)281.00€Cavutilide
CAS:Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.Formula:C22H26FN3O3Purity:99.82% - 99.85%Color and Shape:SolidMolecular weight:399.458
