Bcr-Abl
Bcr-Abl inhibitors are targeted therapies that inhibit the Bcr-Abl fusion protein, which is formed due to the Philadelphia chromosome translocation and is a driver of chronic myeloid leukemia (CML). This protein also influences angiogenesis, contributing to tumor progression. Bcr-Abl inhibitors are crucial in the treatment of CML and are being explored for their potential in inhibiting angiogenesis in various cancers. At CymitQuimica, we provide high-quality Bcr-Abl inhibitors to support your research in cancer biology, angiogenesis, and targeted therapy.
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Imatinib Mesylate
CAS:220127-57-1
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, …
Formula:
C29H31N7O·CH4SO3
Purity:
100% - 99.97%
Color and Shape:
White Crystalline Powder
Molecular weight:
589.71
Ref: TM-T1621
| 1u | 163.20 € | ||
| 200mg | 59.00 € | ||
| 500mg | 89.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Dasatinib monohydrate
CAS:863127-77-9
Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.
Formula:
C22H28ClN7O3S
Purity:
100% - 99.68%
Color and Shape:
Solid
Molecular weight:
506.03
Ref: TM-T1448L
| 50mg | 39.00 € | ||
| 100mg | 55.00 € | ||
| 200mg | 72.00 € | ||
| 500mg | 104.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
N-Desmethyl imatinib
CAS:404844-02-6
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target …
Formula:
C28H29N7O
Purity:
98.60%
Color and Shape:
Off-White To Pale-Yellow Solid
Molecular weight:
479.58
Ref: TM-T11641
| 1mg | 92.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 319.00 € | ||
| 25mg | 540.00 € | ||
| 50mg | 777.00 € | ||
| 100mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 178.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Nilotinib
CAS:641571-10-0
Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be …
Formula:
C28H22F3N7O
Purity:
99.61% - 99.83%
Color and Shape:
Off-White Solid
Molecular weight:
529.52
Ref: TM-T1524
| 50mg | 42.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 55.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
LXH254
CAS:1800398-38-2
LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM …
Formula:
C25H25F3N4O4
Purity:
98.3% - 99.92%
Color and Shape:
Solid
Molecular weight:
502.49
Ref: TM-T11898
| 1mg | 52.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 690.00 € | ||
| 200mg | 948.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Lyn-IN-1
CAS:887650-05-7
Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and Lyn
Formula:
C30H31F3N8O
Purity:
97% - 99.33%
Color and Shape:
Solid
Molecular weight:
576.62
Ref: TM-T11916
| 1mg | 47.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 560.00 € | ||
| 200mg | 815.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Dasatinib
CAS:302962-49-8
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and …
Formula:
C22H26ClN7O2S
Purity:
99.59% - 99.86%
Color and Shape:
Pale-Yellow Solid
Molecular weight:
488.01
Ref: TM-T1448
| 1g | 137.00 € | ||
| 50mg | 44.00 € | ||
| 100mg | 58.00 € | ||
| 200mg | 69.00 € | ||
| 500mg | 95.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Bosutinib
CAS:380843-75-4
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl …
Formula:
C26H29Cl2N5O3
Purity:
98.98% - 99.9%
Color and Shape:
Yellowish-Orange Or Pink To Brownish Solid Solid Powder
Molecular weight:
530.45
Ref: TM-T0152
| 5mg | 39.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 97.00 € | ||
| 500mg | 225.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
AD57
CAS:1093380-42-7
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM …
Formula:
C22H20F3N7O
Purity:
98.23%
Color and Shape:
Soild
Molecular weight:
455.44
Ref: TM-T22552L
| 1mg | 34.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 695.00 € | ||
| 200mg | 939.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
cSRC/BCR-ABL1-IN-1
cSRC/BCR-ABL1-IN-1 (compound 16a) is a dual-target inhibitor of the cSRC/BCR-ABL1 kinases.
Formula:
C24H27ClN6O4
Color and Shape:
Liquid
Molecular weight:
498.96
Ref: TM-T201022
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BCR-ABL-IN-10
BCR-ABL-IN-10 (compound B4) is a covalent BCR-ABL inhibitor featuring an arylvinylsulfonate (AVS) moiety, demonstrating an …
Formula:
C24H22N4O5S
Color and Shape:
Liquid
Molecular weight:
478.52
Ref: TM-T200894
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
DPH
CAS:484049-04-9
DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular …
Formula:
C18H13FN4O2
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
336.32
Ref: TM-T15164
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BCR-ABL-IN-9
BCR-ABL-IN-9 (Compound B1) is an inhibitor of BCR-ABL that achieves sustained suppression through the formation …
Formula:
C22H20N4O3
Color and Shape:
Liquid
Molecular weight:
388.42
Ref: TM-T200990
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AKE-72
CAS:2566525-18-4
AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing …
Formula:
C30H29F3N6O
Purity:
98.3%
Color and Shape:
Soild
Molecular weight:
546.59
Ref: TM-T80676
| 1mg | 156.00 € | ||
| 5mg | 373.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 842.00 € | ||
| 50mg | 1,130.00 € | ||
| 100mg | 1,549.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
c-ABL-IN-5
C-ABL-IN-5, a selective c-Abl inhibitor, exhibits neuroprotective properties and has favorable characteristics including blood-brain barrier …
Formula:
C19H17F2N3O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
341.35
Ref: TM-T79716
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Imatinib impurities3
CAS:404844-11-7
Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for …
Formula:
C24H20ClN5O
Purity:
97.05%
Color and Shape:
Liquid
Molecular weight:
429.9
Ref: TM-T67847
| 10mg | 43.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 135.00 € | ||
| 200mg | 187.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Bosutinib hydrate
CAS:918639-08-4
Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for …
Formula:
C26H31Cl2N5O4
Purity:
99.87%
Color and Shape:
Liquid
Molecular weight:
548.46
Ref: TM-T63875
| 5mg | 39.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 106.00 € | ||
| 100mg | 159.00 € | ||
| 500mg | 311.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
KW-2449
CAS:1000669-72-6
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora …
Formula:
C20H20N4O
Purity:
98.43% - 99.89%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T2341
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 482.00 € | ||
| 500mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
BGG463
CAS:890129-26-7
BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 …
Formula:
C30H29F3N6O3
Purity:
100% - 95.05%
Color and Shape:
Solid
Molecular weight:
578.58
Ref: TM-T4618
| 1mg | 62.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 154.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Asciminib
CAS:1492952-76-7
Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5-0.8nM).
Formula:
C20H18ClF2N5O3
Purity:
97.93% - 99.45%
Color and Shape:
Solid
Molecular weight:
449.84
Ref: TM-T5177
| 1mg | 63.00 € | ||
| 2mg | 92.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 427.00 € | ||
| 100mg | 630.00 € | ||
| 500mg | 1,320.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
