
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(95 products)
- CDK(502 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(226 products)
- Kinesin(68 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(68 products)
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Found 3493 products of "Cell Cycle/Checkpoint"
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2′-O-MOE-AMP
CAS:<p>2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>Formula:C13H20N5O8PColor and Shape:SolidMolecular weight:405.30Aurora B inhibitor 1
CAS:<p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.</p>Formula:C25H26ClF2N7O2Purity:98.37%Color and Shape:SolidMolecular weight:529.97Cdc7-IN-18
CAS:<p>Cdc7-IN-18 (1-2) inhibits CDC7 enzyme (IC50: 1.29 nM) and COLO205 cell proliferation (IC50: 53.62 nM).</p>Formula:C19H21N5OSColor and Shape:SolidMolecular weight:367.47Sovesudil hydrochloride
<p>Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.</p>Formula:C23H23ClFN3O3Color and Shape:SolidMolecular weight:443.9CDK2-IN-40
CAS:<p>CDK9-IN-40 is an inhibitor of CDK2 (Cyclin-dependent kinase 2). It effectively inhibits CDK2/Cyclin E1, with an IC50 of ≤ 10 nM.</p>Formula:C16H21N7O2Color and Shape:SolidMolecular weight:343.384Cdc7-IN-19
CAS:<p>Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1].</p>Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.402'-F-AMP
CAS:<p>2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>Formula:C10H13FN5O6PMolecular weight:349.21LNA-UTP
CAS:<p>LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>Formula:C10H15N2O15P3Color and Shape:SolidMolecular weight:496.15DHX9-IN-19
CAS:<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Formula:C20H21ClN4O4S2Color and Shape:SolidMolecular weight:480.988NusB-IN-1
<p>NusB-IN-1 (22r) is an oral bacterial rRNA inhibitor, effective against MRSA and VRSA.</p>Formula:C21H16N2O3Color and Shape:SolidMolecular weight:344.36Polθ-IN-7
CAS:<p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>Formula:C28H35F3N6O2Color and Shape:SolidMolecular weight:544.612BWC0977
CAS:<p>BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.</p>Formula:C22H21FN6O5Color and Shape:SolidMolecular weight:468.44IXA62
CAS:<p>IXA62 is an orally active, selective IRE1/XBP1s agonist (EC50= 0.31 μM) that can reduce Aβ secretion.</p>Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.458CDK2/4-IN-2
CAS:<p>CDK2/4-IN-2 (compound 56) serves as a dual inhibitor for CDK2 and CDK4, exhibiting an IC50 of less than 100 nM. It is applicable in cancer research.</p>Formula:C18H20F3N7O3S2Color and Shape:SolidMolecular weight:503.52MU147
CAS:<p>MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer properties, exhibiting lethal effects on Ehrlich ascites tumor cells both in vivo and in vitro. It disrupts the MRE11 nuclease-dependent double-strand break repair mechanism without impairing ATM activation. Additionally, MU147 damages the degradation of nascent strands at stalled replication forks and selectively affects BRCA2-deficient cells.</p>Formula:C19H13N3O3SColor and Shape:SolidMolecular weight:363.39Dyrk1A/α-synuclein-IN-2
<p>Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM).</p>Formula:C21H16N4O4SColor and Shape:SolidMolecular weight:420.44Plevitrexed
CAS:<p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53Werner syndrome RecQ helicase-IN-2
CAS:<p>Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.</p>Formula:C32H34F3N9O5Purity:99.02%Color and Shape:SolidMolecular weight:681.67Anticancer agent 29
<p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>Formula:C22H15ClFNOColor and Shape:SolidMolecular weight:363.81RAD51-IN-8
<p>RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.</p>Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21α5β1 integrin agonist-1
CAS:<p>α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.</p>Formula:C24H26FN5O9Color and Shape:SolidMolecular weight:547.49p38α inhibitor 9
CAS:<p>p38α inhibitor9 (Compound 2015) is a p38α inhibitor that effectively blocks the enzyme activity of p38α, with an IC50 of less than 20 nM. It inhibits MK2T334 phosphorylation and activates Cdc25b and Cdc25c while inactivating Wee1, leading to mitotic catastrophe, aneuploidy or polyploidy, and DNA damage. Additionally, p38α inhibitor9 can suppress colorectal cancer (CRC) metastasis.</p>Formula:C27H24FN3O3Color and Shape:SolidMolecular weight:457.496TREX1-IN-3
CAS:<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Formula:C24H19ClN6O4Color and Shape:SolidMolecular weight:490.8983'-Deoxy-GTP
CAS:<p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) is an analog of GTP and serves as an RNA chain terminator, effectively inhibiting RNA synthesis. It can inhibit dengue virus DENV NS5 RdRp with an IC50 of 0.02 μM.</p>Formula:C10H16N5O13P3Color and Shape:SolidMolecular weight:507.181GSK_WRN4
CAS:<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formula:C16H20N2O4SPurity:99.95%Color and Shape:SolidMolecular weight:336.41Fradafiban
CAS:<p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>Formula:C20H21N3O4Purity:98%Color and Shape:SolidMolecular weight:367.40HPH-15
CAS:<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formula:C19H31N3S4Color and Shape:SolidMolecular weight:429.738-Oxo-dATP
CAS:<p>8-Oxo-dATP can be hydrolyzed to its monophosphate form by the oxidation of purine nucleoside triphosphate MTH1, preventing erroneous incorporation during DNA replication or transcription.</p>Formula:C10H12Li4N5O13P3Color and Shape:SolidMolecular weight:530.913Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45CDK4-IN-1
CAS:<p>CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50</p>Formula:C22H29ClN8Purity:98%Color and Shape:SolidMolecular weight:440.97Des-ethyl-carafiban
CAS:<p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>Formula:C22H23N5O5Color and Shape:SolidMolecular weight:437.448L-2'-Fd4C
CAS:<p>L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].</p>Formula:C9H10FN3O3Color and Shape:SolidMolecular weight:227.19NSC 641396
CAS:<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Formula:C18H13NO3Color and Shape:SolidMolecular weight:291.301CDK4/6-IN-13
CAS:<p>Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.</p>Formula:C25H29N7OColor and Shape:SolidMolecular weight:443.54Zeltociclib
CAS:<p>Zeltociclib is an inhibitor of cyclin-dependent kinases (CDKs) with anti-tumor properties.</p>Formula:C18H20F3N4O2PColor and Shape:SolidMolecular weight:412.346DL-Alanosine
CAS:<p>DL-Alanosine is an amino acid analog with antitumor activity.</p>Formula:C3H7N3O4Color and Shape:SolidMolecular weight:149.105Haspin-IN-2
CAS:<p>Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).</p>Formula:C12H8N4O3Color and Shape:SolidMolecular weight:256.22SGC-CLK-1
CAS:<p>SGC-CLK-1 is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. It effectively inhibits the growth of melanoma and glioblastoma cells.</p>Formula:C19H15F3N6O2Color and Shape:SolidMolecular weight:416.36LNA-GMP
CAS:<p>LNA-GMP, a nucleotide analogue, is utilized in the synthesis of oligonucleotides.</p>Formula:C11H14N5O8PColor and Shape:SolidMolecular weight:375.23UMPK ligand 1
CAS:<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Formula:C15H22N4O5SColor and Shape:SolidMolecular weight:370.424USP7-IN-10
CAS:<p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>Formula:C26H29ClN4O3SColor and Shape:SolidMolecular weight:513.05Glycyl H-1152 hydrochloride
CAS:<p>Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.</p>Formula:C18H26Cl2N4O3SColor and Shape:SolidMolecular weight:449.396-B345TTQ
CAS:<p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>Formula:C22H20BrNO4Color and Shape:SolidMolecular weight:442.303Galidesivir
CAS:<p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>Formula:C11H15N5O3Purity:96.73% - 99.13%Color and Shape:SolidMolecular weight:265.27GSK3-IN-10
CAS:<p>GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.</p>Formula:C17H18F2N4O3Color and Shape:SolidMolecular weight:364.347TREX1-IN-4
CAS:<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Formula:C24H19ClN6O4Color and Shape:SolidMolecular weight:490.898MU1409
CAS:<p>MU1409 is an MRE11 nuclease inhibitor with an IC50 of 12.1 μM. It also inhibits FEN1 and EXO1, with IC50 values of 24.2 μM and 176.4 μM, respectively. MU1409 impacts cellular DNA repair and prevents the degradation of stalled replication forks in BRCA2-deficient cells, making it a promising candidate for studying BRCA2 mutation-induced cancers.</p>Formula:C20H14BrN3O3SColor and Shape:SolidMolecular weight:456.312LIMK1 inhibitor 2
CAS:<p>LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with an IC50 value of 9 μM.</p>Formula:C10H11N3OSColor and Shape:SolidMolecular weight:221.279WEE1/PKMYT1-IN-1
CAS:<p>WEE1/PKMYT1-IN-1 (compound 75) is an effective and orally bioavailable inhibitor of WEE1 and PKMYT1. It demonstrates antiproliferative activity.</p>Formula:C16H16N4O3Color and Shape:SolidMolecular weight:312.323LNA-GDP
CAS:<p>LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>Formula:C11H15N5O11P2Color and Shape:SolidMolecular weight:455.21CDK4/6-IN-24
CAS:<p>CDK4/6-IN-24 (Compound A) is an inhibitor of CDK4/6 with broad-spectrum antitumor activity. It can effectively inhibit various cancer cells, exhibiting an IC50 in the submicromolar range.</p>Formula:C32H41N7O3Color and Shape:SolidMolecular weight:571.713DYRK1-IN-1
CAS:<p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>Formula:C12H12N6Color and Shape:SolidMolecular weight:240.26MtTMPK-IN-9
<p>MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.</p>Formula:C25H26N6O7Color and Shape:SolidMolecular weight:522.51FR-β ligand 1
CAS:<p>FR-β ligand 1 (III) is a ligand that specifically targets folate receptors, exhibiting antitumor activity, high selectivity, and strong affinity.</p>Formula:C22H25N5O6Color and Shape:SolidMolecular weight:455.46MY05
CAS:<p>MY05 selectively targets c-MYC within cells and disrupts the interaction between MYC and MAX. It binds to intracellular c-MYC, modulating its thermal stability, reducing the transcriptional targets of c-MYC, and exhibiting anticancer activity (TNBC, triple-negative breast cancer).</p>Formula:C19H11ClN4OColor and Shape:SolidMolecular weight:346.772′-F-UDP
CAS:<p>2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>Formula:C9H13FN2O11P2Color and Shape:SolidMolecular weight:406.15TA-316
CAS:<p>Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.</p>Formula:C28H25BrN4O5S2Purity:98%Color and Shape:SolidMolecular weight:641.56PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065Aurora A inhibitor 1
CAS:<p>Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)</p>Formula:C25H28ClF2N5O2Color and Shape:SolidMolecular weight:503.97PD-1/PD-L1-IN-53
CAS:<p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>Formula:C31H37N3O4Color and Shape:SolidMolecular weight:515.64CDK1-IN-7
CAS:<p>CDK1-IN-7 (compound M7) is a potent CDK1 inhibitor. It effectively suppresses the proliferation and migration of HCT116 and Lovo cells, making it a valuable tool for colorectal cancer research.</p>Formula:C23H19ClN4O3Color and Shape:SolidMolecular weight:434.88N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
CAS:<p>N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that resembles the natural nucleotide adenosine in structure. It acts as an activator of ribonucleotide reductase, facilitating the conversion of ribonucleotides into deoxyribonucleotides.</p>Formula:C38H35N5O6Color and Shape:SolidMolecular weight:657.714RNAP-σ interaction inhibitor-1
CAS:<p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>Formula:C19H11Cl3N2O6S2Color and Shape:SolidMolecular weight:533.79MTH1 activator-1
CAS:<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formula:C29H23F3N4O2Color and Shape:SolidMolecular weight:516.514CDK2-IN-30
CAS:<p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>Formula:C18H25N7O3SColor and Shape:SolidMolecular weight:419.50PAIR2
CAS:<p>PAIR2 is a selective IRE1α RNase partial antagonist, blocking its ATP site and preventing KIRA from hindering XBP1 splicing.</p>Formula:C27H26F4N6O3SColor and Shape:SolidMolecular weight:590.59Elacytarabine
CAS:<p>Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.</p>Formula:C27H45N3O6Purity:97.69%Color and Shape:SolidMolecular weight:507.66HRO761
CAS:<p>HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.</p>Formula:C31H31ClF3N9O5Purity:98.74% - 99.62%Color and Shape:SolidMolecular weight:702.08CTPS1-IN-1
CAS:<p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>Formula:C21H22N6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:486.57GFB-12811
CAS:<p>GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.</p>Formula:C22H23F4N5OPurity:98.88%Color and Shape:SolidMolecular weight:449.44SR 11302
CAS:<p>SR 11302 is an inhibitor of activator protein-1 (AP-1).</p>Formula:C26H32O2Purity:98.65%Color and Shape:SolidMolecular weight:376.53LY3143921 hydrate
CAS:<p>LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].</p>Formula:C16H14FN5O2Purity:98.43%Color and Shape:SolidMolecular weight:327.31INCB086550
CAS:<p>INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.</p>Formula:C41H39N7O4Purity:98.49%Color and Shape:SolidMolecular weight:693.79Deoxypseudouridine
CAS:<p>Deoxypseudouridine is a nucleotide analog.</p>Formula:C9H12N2O5Color and Shape:SolidMolecular weight:228.2Bicyclomycin benzoate
CAS:<p>Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.</p>Formula:C19H22N2O8Color and Shape:SolidMolecular weight:406.39Troxacitabine
CAS:<p>Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.</p>Formula:C8H11N3O4Purity:98%Color and Shape:SolidMolecular weight:213.19N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
CAS:<p>N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.</p>Formula:C38H35N5O6Color and Shape:SolidMolecular weight:657.7275'-DMT-3'-TBDMS-ibu-rG
CAS:<p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>Formula:C41H51N5O8SiColor and Shape:SolidMolecular weight:769.96Formycin A
CAS:<p>Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.</p>Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.245'-O-TBDMS-dT
CAS:<p>5’-O-TBDMS-dT is a nucleoside with protective and modification effects.</p>Formula:C16H28N2O5SiColor and Shape:SolidMolecular weight:356.49Tanuxiciclib
CAS:<p>Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.</p>Formula:C15H13FN6OColor and Shape:SolidMolecular weight:312.308NSC639828
CAS:<p>NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.</p>Formula:C18H13BrClN5O3Color and Shape:SolidMolecular weight:462.695'-O-DMT-N6-ibu-dA
CAS:<p>5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.</p>Formula:C35H37N5O6Color and Shape:SolidMolecular weight:623.71Ethynylcytidine
CAS:<p>Ethynylcytidine is a nucleoside antimetabolite.</p>Formula:C11H13N3O5Purity:98%Color and Shape:SolidMolecular weight:267.242'-Deoxy-2'-fluoro-5-iodouridine
CAS:<p>2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.</p>Formula:C9H10FIN2O5Color and Shape:SolidMolecular weight:372.09GSK-3/CDK5/CDK2-IN-1
CAS:<p>GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].</p>Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.433PLK1-IN-6
<p>PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.</p>Formula:C28H37N9O3Color and Shape:SolidMolecular weight:547.65Ribocil-C
CAS:<p>Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.</p>Formula:C21H21N7OSPurity:98%Color and Shape:SolidMolecular weight:419.5MitoE10
CAS:<p>MitoE10 is an effective mitochondrial targeting antioxidant.</p>Formula:C42H55O5PSColor and Shape:SolidMolecular weight:702.926-Amino-5-nitropyridin-2-one
CAS:<p>6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.</p>Formula:C5H5N3O3Purity:98%Color and Shape:SolidMolecular weight:155.11Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Formula:C28H32F2N8Purity:98%Color and Shape:SolidMolecular weight:518.6PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44YK-2168
CAS:<p>YK-2168 is a differentiated selective inhibitor of CDK9.</p>Formula:C16H18ClN5Color and Shape:SolidMolecular weight:315.80Ref: TM-T200769
Discontinued product

