Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(233 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(128 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
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Found 3935 products of "Cell Cycle/Checkpoint"
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ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Formula:C9H13N3Na3O12P3Color and Shape:SolidMolecular weight:517.1YKL-1-116
CAS:YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.Formula:C34H38N8O3Purity:98%Color and Shape:SolidMolecular weight:606.72PROTAC CDK12/13 Degrader-1
PROTAC CDK12/13 Degrader-1 (7f) selectively degrades CDK12/13 at nanomolar potency, targeting breast cancer.Color and Shape:SolidCDK8-IN-5
CAS:CDK8-IN-5: potent CDK8 inhibitor, IC50=72 nM, boosts IL-10 by 43%, may aid inflammatory bowel disease research.Formula:C26H22N2O4Color and Shape:SolidMolecular weight:426.46Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Formula:C22H29FN3O10PColor and Shape:SolidMolecular weight:545.457ART615
ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).Formula:C21H21F3N4O2Color and Shape:SolidMolecular weight:418.41Elacytarabine
CAS:Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.Formula:C27H45N3O6Purity:97.69%Color and Shape:SolidMolecular weight:507.66HRO761
CAS:HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Formula:C31H31ClF3N9O5Purity:98.74% - 99.62%Color and Shape:SolidMolecular weight:702.08Ref: TM-T72107
1mg57.00€5mg118.00€10mg167.00€25mg280.00€50mg475.00€100mg708.00€1mL*10mM (DMSO)778.00€VCPIP1-IN-1
CAS:VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.Formula:C13H15ClN2O2Purity:99.3%Color and Shape:SolidMolecular weight:266.72Ref: TM-T88664
1mg47.00€5mg92.00€1mL*10mM (DMSO)101.00€10mg145.00€25mg281.00€50mg447.00€100mg715.00€200mg964.00€CTPS1-IN-1
CAS:CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Formula:C21H22N6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:486.57USP15-IN-1
CAS:USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).Formula:C22H23N3O3Purity:99.509% - 99.81%Color and Shape:SolidMolecular weight:377.44GFB-12811
CAS:GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.Formula:C22H23F4N5OPurity:98.88%Color and Shape:SolidMolecular weight:449.44Zelasudil
CAS:Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formula:C22H21F2N7OPurity:99.15%Color and Shape:SolidMolecular weight:437.445Ref: TM-T69665
1mg69.00€5mg147.00€1mL*10mM (DMSO)164.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Formula:C26H32O2Purity:98.65%Color and Shape:SolidMolecular weight:376.53Ref: TM-T23384
1mg93.00€5mg137.00€1mL*10mM (DMSO)150.00€10mg205.00€25mg356.00€50mg587.00€100mg888.00€LY3143921 hydrate
CAS:LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].Formula:C16H14FN5O2Purity:98.43%Color and Shape:SolidMolecular weight:327.31INCB086550
CAS:INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.Formula:C41H39N7O4Purity:98.49%Color and Shape:SolidMolecular weight:693.79Troxacitabine
CAS:Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.Formula:C8H11N3O4Purity:98%Color and Shape:SolidMolecular weight:213.19Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formula:C19H22N2O8Color and Shape:SolidMolecular weight:406.39Formycin A
CAS:Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.24PLK1-IN-6
PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.
Formula:C28H37N9O3Color and Shape:SolidMolecular weight:547.65GSK-3/CDK5/CDK2-IN-1
CAS:GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.433N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
CAS:N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.Formula:C38H35N5O6Color and Shape:SolidMolecular weight:657.727Tanuxiciclib
CAS:Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.Formula:C15H13FN6OColor and Shape:SolidMolecular weight:312.308NSC639828
CAS:NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Formula:C18H13BrClN5O3Color and Shape:SolidMolecular weight:462.695'-O-DMT-N6-ibu-dA
CAS:5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Formula:C35H37N5O6Color and Shape:SolidMolecular weight:623.713BrB-PP1
CAS:3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase, particularly effective against protein kinases with mutations in the ATP-binding pocket, such as the Thr97 mutation within Sty1's ATP-binding pocket.Formula:C16H18BrN5Color and Shape:SolidMolecular weight:360.2595'-DMT-3'-TBDMS-ibu-rG
CAS:5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.Formula:C41H51N5O8SiColor and Shape:SolidMolecular weight:769.96Ethynylcytidine
CAS:Ethynylcytidine is a nucleoside antimetabolite.Formula:C11H13N3O5Purity:98%Color and Shape:SolidMolecular weight:267.242'-Deoxy-2'-fluoro-5-iodouridine
CAS:2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.Formula:C9H10FIN2O5Color and Shape:SolidMolecular weight:372.09MitoE10
CAS:MitoE10 is an effective mitochondrial targeting antioxidant.Formula:C42H55O5PSColor and Shape:SolidMolecular weight:702.92Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formula:C21H21N7OSPurity:99.69%Color and Shape:SolidMolecular weight:419.56-Amino-5-nitropyridin-2-one
CAS:6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.Formula:C5H5N3O3Purity:98%Color and Shape:SolidMolecular weight:155.11Tibremciclib
CAS:Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].
Formula:C28H32F2N8Purity:98%Color and Shape:SolidMolecular weight:518.6PHI-101
CAS:PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.
Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44YK-2168
CAS:YK-2168 is a differentiated selective inhibitor of CDK9.
Formula:C16H18ClN5Color and Shape:SolidMolecular weight:315.80Ref: TM-T200769
Discontinued product
