Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(250 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3869 products of "Cell Cycle/Checkpoint"
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NSC47924
CAS:NSC47924 is a laminin receptor (LR) inhibitor.Formula:C18H17NO2Purity:98%Color and Shape:SolidMolecular weight:279.333'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formula:C9H15N2O14P3Color and Shape:SolidMolecular weight:468.14MDK6204
CAS:MDK6204 is a selective inhibitor of CLK1 and CLK2.Formula:C20H20N6OPurity:98%Color and Shape:SolidMolecular weight:360.41Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Formula:C15H21N5O7SColor and Shape:SolidMolecular weight:415.42Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Color and Shape:SolidMolecular weight:435.86LSN 3213128
CAS:LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.Formula:C17H16FN3O4S2Color and Shape:SolidMolecular weight:409.45R-82913
CAS:R-82913 blocks RNA-polymerase, lowers mouse DOI-head-shakes, halts 13 HIV-1 strains with 0.15µM IC50, beats AZT-TP by 20x; ineffective on HIV-2.Formula:C16H20ClN3SColor and Shape:SolidMolecular weight:321.87UCK2 Inhibitor-1
CAS:UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 µM .Formula:C27H21N3O4SColor and Shape:SolidMolecular weight:483.54RTC14
CAS:RTC14 induces PTC readthrough, restoring dystrophin and aiding muscle function in Duchenne model mice.Formula:C17H18N2O3Color and Shape:SolidMolecular weight:298.34Epiroprim
CAS:Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor with antibacterial activity, inhibiting Staphylococcus and Streptococcus.Formula:C19H23N5O2Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:353.42Myt1-IN-1
CAS:Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].Formula:C16H15ClN4O2Color and Shape:SolidMolecular weight:330.7712(S)-HpETE
CAS:12(S)-HpETE activates human blood leukocyte 5-LOE and mediates induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Color and Shape:SolidMolecular weight:291.71AB-182
CAS:AB-182 is an aziridine derivative with antitumor activity.Formula:C11H22N3O4PColor and Shape:SolidMolecular weight:291.28IRE1α kinase-IN-7
CAS:IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFormula:C28H25F3N6OColor and Shape:SolidMolecular weight:518.53WF-536 Hydrochloride
CAS:WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.Formula:C14H16ClN3OColor and Shape:SolidMolecular weight:277.75Ro 43-5054
CAS:Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.Formula:C24H27N5O7Purity:98%Color and Shape:SolidMolecular weight:497.5β-catenin-IN-3
CAS:β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces theFormula:C19H20Br2N2OSColor and Shape:SolidMolecular weight:484.25ROCK-IN-D1
CAS:ROCK-IN-D1 is an effective and selective inhibitor of ROCK.Formula:C22H27N5O2SPurity:98%Color and Shape:SolidMolecular weight:425.55BA-1049
CAS:BA-1049 is a selective ROCK2 inhibitor.Formula:C16H21N3O2SColor and Shape:SolidMolecular weight:319.42XIE18-6
CAS:XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.Formula:C18H15NO6SPurity:99.712%Color and Shape:SolidMolecular weight:373.38Cdc7-IN-17
CAS:Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Formula:C13H15N5OSColor and Shape:SolidMolecular weight:289.36AZD7762 HCl
CAS:AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.Formula:C17H20ClFN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.88VPC-70619
CAS:VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.Formula:C16H8ClF3N4OColor and Shape:SolidMolecular weight:364.71CI-898 HCl
CAS:CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.Formula:C19H26Cl3N5O3Color and Shape:SolidMolecular weight:478.8Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Color and Shape:SolidMolecular weight:394.51SNX2-1-108
CAS:SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.Formula:C21H16N4Purity:98%Color and Shape:SolidMolecular weight:324.38VRX-0466617
CAS:VRX-0466617 is a novel selective Chk2 inhibitor.Formula:C19H20BrN5O2SColor and Shape:SolidMolecular weight:462.36CDK4/6-IN-14
CAS:CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.Formula:C24H27ClFN7OColor and Shape:SolidMolecular weight:483.97LIMK-IN-14
CAS:LIMK-IN-14 is an effective and selective inhibitor of LIMK.Formula:C22H27N7O3Purity:98%Color and Shape:SolidMolecular weight:437.49CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formula:C16H18N2O7SPurity:99.95%Color and Shape:SolidMolecular weight:382.39CCT245737(S)
CAS:CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.Formula:C16H16F3N7OColor and Shape:SolidMolecular weight:379.34Photoregulin3
CAS:Photoregulin3 is a inhibitor of rod photoreceptor gene expression, potentially though Nr2e3 modulation.Formula:C22H23N3O3Color and Shape:SolidMolecular weight:377.44DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Formula:C17H13ClN2O2Purity:99.78%Color and Shape:SolidMolecular weight:312.75Ref: TM-T11030
1mg109.00€2mg163.00€5mg241.00€10mg354.00€25mg532.00€50mg745.00€100mg1,018.00€500mgTo inquire1mL*10mM (DMSO)235.00€Trimetrexate glucuronate
CAS:Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.Formula:C25H33N5O10Color and Shape:SolidMolecular weight:563.564BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4TCS 2314
CAS:TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59Denopterin
CAS:Denopterin is an antineoplastic agent.Formula:C21H23N7O6Purity:98%Color and Shape:SolidMolecular weight:469.45Crisnatol
CAS:Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Formula:C23H23NO2Color and Shape:SolidMolecular weight:345.43GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82ROCK-IN-4
CAS:ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.Formula:C20H26ClFN4O7SColor and Shape:SolidMolecular weight:520.96CDK-IN-10
CAS:CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.Formula:C18H18N4O2Purity:97.07%Color and Shape:SolidMolecular weight:322.36Atuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43USP28-IN-2
CAS:USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.Formula:C23H20Cl2N2O3SColor and Shape:SolidMolecular weight:475.39SP-471P
CAS:SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.Formula:C33H26BrN5O2Color and Shape:SolidMolecular weight:604.5JH-XIV-68-3
CAS:JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.Formula:C21H17F3N8OColor and Shape:SolidMolecular weight:454.41Akt1&PKA-IN-2
CAS:Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.Formula:C20H17Cl2N3OColor and Shape:SolidMolecular weight:386.27CDK1-IN-1
CAS:CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.Formula:C27H23N5O3Color and Shape:SolidMolecular weight:465.5FLDP-5
CAS:FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.4CDK7-IN-2
CAS:CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.Formula:C26H39N7O3Color and Shape:SolidMolecular weight:497.63CB10-277
CAS:CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.Formula:C9H11N3O2Color and Shape:SolidMolecular weight:193.2Edatrexate
CAS:Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.Formula:C22H25N7O5Color and Shape:SolidMolecular weight:467.48Erythromycin hydrochloride
CAS:Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.Formula:C37H68ClNO13Color and Shape:SolidMolecular weight:770.39HBV-IN-21
CAS:HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Formula:C17H17FN4OS2Color and Shape:SolidMolecular weight:376.47Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Formula:C9H9N5O5Purity:98%Color and Shape:SolidMolecular weight:267.2CDK4/6-IN-7
CAS:CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.Formula:C18H18ClN5O3Color and Shape:SolidMolecular weight:387.821-Acetyl-3-o-toluyl-5-fluorouracil
CAS:1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.Formula:C14H11FN2O4Purity:98%Color and Shape:SolidMolecular weight:290.25CAY10760
CAS:CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.Formula:C28H24ClN3O3Color and Shape:SolidMolecular weight:485.96Rabacfosadine succinate
CAS:Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.Formula:C25H41N8O10PPurity:98%Color and Shape:SolidMolecular weight:644.623DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84TH470
CAS:TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,Formula:C30H31N5O5S2Color and Shape:SolidMolecular weight:605.73Ryuvidine
CAS:Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.Formula:C15H12N2O2SPurity:98.6%Color and Shape:SolidMolecular weight:284.33Netivudine
CAS:Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.Formula:C12H14N2O6Purity:99.78%Color and Shape:SolidMolecular weight:282.25D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formula:C23H36N6SPurity:99.65%Color and Shape:SolidMolecular weight:428.64Ref: TM-T10936
1mg34.00€5mg73.00€10mg119.00€25mg236.00€50mg353.00€100mg517.00€200mg737.00€1mL*10mM (DMSO)80.00€DDRI-18
CAS:DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.Formula:C26H20N6Purity:98%Color and Shape:SolidMolecular weight:416.48Talviraline
CAS:Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFormula:C15H20N2O3S2Purity:99.88%Color and Shape:SolidMolecular weight:340.46DENV-IN-5
CAS:Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.Formula:C23H25ClF2N4OSPurity:99.42%Color and Shape:SolidMolecular weight:478.99Ref: TM-T63143
1mg424.00€5mg964.00€10mg1,288.00€25mg1,890.00€50mg2,322.00€100mg3,060.00€1mL*10mM (DMSO)898.00€ERCC1-XPF-IN-2
CAS:ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).
Formula:C15H13Cl2NO3Purity:98.21%Color and Shape:SolidMolecular weight:326.17Ref: TM-T60904
2mg40.00€5mg60.00€10mg96.00€25mg187.00€50mg311.00€100mg472.00€200mg658.00€500mg1,026.00€CHK1-IN-3
CAS:CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Formula:C20H23N9OPurity:98.78%Color and Shape:SolidMolecular weight:405.46Ref: TM-T10791
1mg168.00€2mg231.00€5mg371.00€10mg558.00€25mg868.00€50mg1,153.00€100mg1,575.00€200mg2,125.00€1mL*10mM (DMSO)423.00€CDK9-IN-10
CAS:CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.Formula:C22H16O5Purity:99.8%Color and Shape:SolidMolecular weight:360.36dCeMM2
CAS:dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Formula:C16H11ClN6OSPurity:99.68%Color and Shape:SolidMolecular weight:370.82Ref: TM-T61477
1mg37.00€5mg79.00€10mg119.00€25mg250.00€50mg426.00€100mg633.00€500mg1,349.00€1mL*10mM (DMSO)110.00€ITX3
CAS:ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Formula:C22H17N3OSPurity:97.28%Color and Shape:SolidMolecular weight:371.45SB-747651A Dihydrochloride
CAS:SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Formula:C16H24Cl2N8OPurity:98.05%Color and Shape:SolidMolecular weight:415.32Ref: TM-T9652
1mg70.00€5mg146.00€10mg207.00€25mg349.00€50mg497.00€100mg675.00€500mgTo inquire1mL*10mM (DMSO)160.00€GS-6620 PM
CAS:GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.Formula:C13H15N5O4Purity:98.52% - 98.7%Color and Shape:SolidMolecular weight:305.29GSK2643943A
CAS:GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.Formula:C17H12FN3Purity:97.09%Color and Shape:SolidMolecular weight:277.3Ref: TM-T11485
1mg39.00€2mg50.00€5mg82.00€10mg120.00€25mg236.00€50mg356.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)90.00€OTUB1/USP8-IN-1
CAS:OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.Formula:C22H16ClFN2O4Purity:98.59%Color and Shape:SoildMolecular weight:426.83SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purity:99.54%Color and Shape:SolidMolecular weight:378.38Ref: TM-T23321
1mg39.00€5mg82.00€10mg123.00€25mg250.00€50mg394.00€100mg618.00€200mg874.00€1mL*10mM (DMSO)69.00€YK-2-69
CAS:YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Formula:C25H27FN8OSPurity:98.61% - 99.64%Color and Shape:SolidMolecular weight:506.6TTP-8307
CAS:TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Formula:C27H21FN4OPurity:98.95%Color and Shape:SolidMolecular weight:436.48Ref: TM-T13221
1mg100.00€5mg236.00€10mg380.00€25mg740.00€50mg1,108.00€100mg1,791.00€200mg2,412.00€1mL*10mM (DMSO)286.00€10-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Formula:C20H19N7O7Purity:99.97%Color and Shape:SolidMolecular weight:469.41CRT0066854 hydrochloride
CAS:CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Formula:C24H27Cl2N5SPurity:99.63%Color and Shape:SolidMolecular weight:488.48Ref: TM-T10888
1mg57.00€5mg122.00€10mg192.00€25mg324.00€50mg459.00€100mg642.00€200mg888.00€1mL*10mM (DMSO)146.00€SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formula:C24H27N5O2Purity:99.14%Color and Shape:SolidMolecular weight:417.5Ref: TM-T73475
1mg111.00€5mg264.00€10mg424.00€25mg838.00€50mg1,035.00€100mg1,396.00€1mL*10mM (DMSO)283.00€Eprociclovir
CAS:Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFormula:C11H15N5O3Purity:98.50% - 99.86%Color and Shape:SolidMolecular weight:265.279-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formula:C17H22N6OPurity:99.82%Color and Shape:SolidMolecular weight:326.4Ref: TM-T23589
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€1mL*10mM (DMSO)607.00€Rho-Kinase-IN-1
CAS:Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formula:C20H24N4SPurity:99.8%Color and Shape:SolidMolecular weight:352.5Ref: TM-T12721
1mg71.00€5mg138.00€10mg205.00€25mg358.00€50mg502.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)105.00€AS 1892802
CAS:AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formula:C20H19N3O2Purity:99.86%Color and Shape:SolidMolecular weight:333.38Ref: TM-T22037
1mg49.00€5mg92.00€10mg166.00€25mg358.00€50mg530.00€100mg758.00€200mg1,044.00€1mL*10mM (DMSO)109.00€6-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.
Formula:C9H11NO5Purity:97.78% - 97.95%Color and Shape:SolidMolecular weight:213.19RP-6685
CAS:RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Formula:C22H14F7N5OPurity:99.65%Color and Shape:SoildMolecular weight:497.37Ref: TM-T60187
1mg84.00€5mg152.00€10mg219.00€25mg358.00€50mg510.00€100mg715.00€1mL*10mM (DMSO)167.00€ProINDY
CAS:ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.Formula:C14H15NO3SPurity:97.19%Color and Shape:SolidMolecular weight:277.34INDY
CAS:INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.Formula:C12H13NO2SPurity:99.26%Color and Shape:SolidMolecular weight:235.3CHD1Li 6.11
CAS:CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.Formula:C21H22BrN5OSPurity:99.04%Color and Shape:SolidMolecular weight:472.4Ref: TM-T63049
1mg92.00€5mg216.00€10mg354.00€25mg597.00€50mg852.00€100mg1,159.00€500mg2,327.00€1mL*10mM (DMSO)227.00€NR2F6 modulator-1
CAS:NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.Formula:C23H17NO5SPurity:98.31%Color and Shape:SolidMolecular weight:419.45Ref: TM-T62204
1mg92.00€5mg188.00€10mg283.00€25mg530.00€50mg742.00€100mg1,035.00€1mL*10mM (DMSO)215.00€Abemaciclib metabolite M20
CAS:Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。Formula:C27H32F2N8OPurity:98.1% - 99.08%Color and Shape:SolidMolecular weight:522.59Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormula:C27H27F2NO6Purity:99.67%Color and Shape:SolidMolecular weight:499.5Ref: TM-TQ0291
1mg44.00€5mg93.00€10mg133.00€25mg268.00€50mg439.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)92.00€SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formula:C15H18Br2N4Purity:99.764% - 99.84%Color and Shape:SolidMolecular weight:414.14Ref: TM-T10744
1mg612.00€5mg1,529.00€10mg1,880.00€25mg2,178.00€50mg2,862.00€100mg3,870.00€1mL*10mM (DMSO)1,835.00€TC-S 7005
CAS:TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Formula:C21H17N3O3Purity:99.516%Color and Shape:SolidMolecular weight:359.38Ref: TM-T17008
1mg57.00€2mg84.00€5mg125.00€10mg188.00€25mg354.00€50mg532.00€100mg712.00€500mgTo inquire1mL*10mM (DMSO)138.00€AzddMeC
CAS:AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFormula:C10H14N6O3Purity:97.14% - 99.62%Color and Shape:SolidMolecular weight:266.26Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formula:C14H11BrN4O3SPurity:97.27%Color and Shape:SolidMolecular weight:395.23Ref: TM-T36933
1mg98.00€2mg133.00€5mg192.00€10mg289.00€25mg485.00€50mg692.00€100mg945.00€500mg1,873.00€
