Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(253 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3872 products of "Cell Cycle/Checkpoint"
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USP30 inhibitor 11
CAS:USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.Formula:C17H16N6O2SPurity:98.84% - 99.59%Color and Shape:SolidMolecular weight:368.4110-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Formula:C20H19N7O7Purity:99.97%Color and Shape:SolidMolecular weight:469.41Talotrexin ammonium
CAS:Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.
Formula:C27H30N10O6Purity:97.49%Color and Shape:SolidMolecular weight:590.59Ref: TM-T64295
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€COH34
CAS:COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.Formula:C18H15NOSPurity:99.57%Color and Shape:SolidMolecular weight:293.38L82
CAS:L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.Formula:C11H8ClN5O4Purity:98.06% - 98.91%Color and Shape:SolidMolecular weight:309.67Ref: TM-T60753
5mg70.00€10mg103.00€25mg187.00€50mg298.00€100mg472.00€500mg1,026.00€1mL*10mM (DMSO)77.00€AS-0141
CAS:AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。Formula:C21H22F3N5O4Purity:99.97%Color and Shape:SolidMolecular weight:465.43Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formula:C12H11N5OPurity:99.27% - 99.9%Color and Shape:SolidMolecular weight:241.25Ref: TM-T12399
1mg108.00€5mg260.00€10mg416.00€25mg690.00€50mg964.00€100mg1,305.00€500mg2,592.00€1mL*10mM (DMSO)286.00€AS 1892802
CAS:AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formula:C20H19N3O2Purity:99.86%Color and Shape:SolidMolecular weight:333.38Ref: TM-T22037
1mg49.00€5mg92.00€10mg166.00€25mg358.00€50mg530.00€100mg758.00€200mg1,044.00€1mL*10mM (DMSO)109.00€CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formula:C11H8F3N3OPurity:98.48%Color and Shape:SolidMolecular weight:255.2Ref: TM-T10740
1mg87.00€5mg216.00€10mg311.00€25mg525.00€50mg707.00€100mg944.00€1mL*10mM (DMSO)240.00€6RK73
CAS:6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).Formula:C13H17N5O2SPurity:99.91%Color and Shape:SolidMolecular weight:307.37Ref: TM-T10188
1mg144.00€5mg298.00€10mg510.00€25mg825.00€50mg1,130.00€100mg1,510.00€500mg3,060.00€1mL*10mM (DMSO)328.00€SJB3-019A
CAS:SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 timesFormula:C16H8N2O3Purity:99.72%Color and Shape:SolidMolecular weight:276.25Ref: TM-T12926
1mg77.00€2mg101.00€5mg168.00€10mg253.00€25mg416.00€50mg580.00€100mg783.00€200mg1,054.00€Abemaciclib metabolite M20
CAS:Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。Formula:C27H32F2N8OPurity:98.1% - 99.08%Color and Shape:SolidMolecular weight:522.59HA-1004
CAS:HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.Formula:C12H15N5O2SPurity:99.56% - 99.63%Color and Shape:SolidMolecular weight:293.34GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formula:C22H23ClN6O2Purity:99.37%Color and Shape:SolidMolecular weight:438.91Ref: TM-T62518
1mg54.00€5mg114.00€10mg178.00€25mg409.00€50mg708.00€100mg1,153.00€1mL*10mM (DMSO)126.00€EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Formula:C18H14FN5O2SPurity:98.43%Color and Shape:SolidMolecular weight:383.4Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47CMX-521
CAS:CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Formula:C13H17N5O5Purity:99.57%Color and Shape:SolidMolecular weight:323.3AzddMeC
CAS:AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFormula:C10H14N6O3Purity:97.14% - 99.62%Color and Shape:SolidMolecular weight:266.26Antiviral agent 17
CAS:Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.Formula:C11H14N4O4Purity:99.89%Color and Shape:SolidMolecular weight:266.25CDK4/6/1 Inhibitor
CAS:CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).Formula:C28H30F2N6Purity:97.25% - 99.72%Color and Shape:SolidMolecular weight:488.57CQ211
CAS:CQ211 is a potent selective RIOK2 inhibitor, Kd 6.1 nM, effectively inhibits cancer cell line proliferation.Formula:C26H22F3N7O2Purity:97.01% - 98.31%Color and Shape:SolidMolecular weight:521.49INDY
CAS:INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.Formula:C12H13NO2SPurity:99.26%Color and Shape:SolidMolecular weight:235.3Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormula:C27H27F2NO6Purity:99.67%Color and Shape:SolidMolecular weight:499.5Ref: TM-TQ0291
1mg44.00€5mg93.00€10mg133.00€25mg268.00€50mg439.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)92.00€DDRI-18
CAS:DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.Formula:C26H20N6Purity:98%Color and Shape:SolidMolecular weight:416.48BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.84%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€DSS30
CAS:DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.Formula:C16H14ClNO3S2Purity:99.19% - 99.4%Color and Shape:SolidMolecular weight:367.87Cytembena
CAS:Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Formula:C11H8BrNaO4Purity:99.7%Color and Shape:White PowderMolecular weight:307.07Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formula:C14H11BrN4O3SPurity:97.27%Color and Shape:SolidMolecular weight:395.23Ref: TM-T36933
1mg98.00€2mg133.00€5mg192.00€10mg289.00€25mg485.00€50mg692.00€100mg945.00€500mg1,873.00€DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formula:C28H31F3N4O6SPurity:98.19% - >99.99%Color and Shape:SolidMolecular weight:608.63Ref: TM-T11103
1mg109.00€5mg260.00€10mg409.00€25mg737.00€50mg1,198.00€100mg1,611.00€1mL*10mM (DMSO)358.00€Eprociclovir
CAS:Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFormula:C11H15N5O3Purity:98.50% - 99.86%Color and Shape:SolidMolecular weight:265.27GKI-1
CAS:GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.Formula:C15H12ClN3Purity:99.96%Color and Shape:SolidMolecular weight:269.73Ref: TM-T11402
1mg93.00€5mg200.00€10mg299.00€25mg485.00€50mg658.00€100mg892.00€1mL*10mM (DMSO)215.00€SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formula:C15H18Br2N4Purity:99.764% - 99.84%Color and Shape:SolidMolecular weight:414.14Ref: TM-T10744
1mg612.00€5mg1,529.00€10mg1,880.00€25mg2,178.00€50mg2,862.00€100mg3,870.00€1mL*10mM (DMSO)1,835.00€Rho-Kinase-IN-1
CAS:Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formula:C20H24N4SPurity:99.8%Color and Shape:SolidMolecular weight:352.5Ref: TM-T12721
1mg71.00€5mg138.00€10mg205.00€25mg358.00€50mg502.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)105.00€CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formula:C26H25F3N8OPurity:99.99%Color and Shape:SolidMolecular weight:522.52CF-1743
CAS:CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.
Formula:C22H26N2O5Purity:99.6% - 99.79%Color and Shape:SolidMolecular weight:398.45ProINDY
CAS:ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.Formula:C14H15NO3SPurity:97.19%Color and Shape:SolidMolecular weight:277.34ML 315
CAS:ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Formula:C18H13Cl2N3O2Purity:99.08%Color and Shape:SolidMolecular weight:374.22UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formula:C17H17N3SPurity:99.86%Color and Shape:SolidMolecular weight:295.4Haspin-IN-3
CAS:Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
Formula:C16H10N2O3Purity:98.78%Color and Shape:SolidMolecular weight:278.269-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formula:C17H22N6OPurity:99.82%Color and Shape:SolidMolecular weight:326.4Ref: TM-T23589
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€1mL*10mM (DMSO)607.00€SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formula:C24H27N5O2Purity:99.14%Color and Shape:SolidMolecular weight:417.5Ref: TM-T73475
1mg111.00€5mg264.00€10mg424.00€25mg838.00€50mg1,035.00€100mg1,396.00€1mL*10mM (DMSO)283.00€PS423
CAS:PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.Formula:C25H23F3O9Purity:98.81% - 99.26%Color and Shape:SolidMolecular weight:524.44Anticancer agent 73
CAS:Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.Formula:C14H15NO4Purity:99.56%Color and Shape:SolidMolecular weight:261.27ERCC1-XPF-IN-2
CAS:ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).
Formula:C15H13Cl2NO3Purity:98.21%Color and Shape:SolidMolecular weight:326.17Ref: TM-T60904
2mg40.00€5mg60.00€10mg96.00€25mg187.00€50mg311.00€100mg472.00€200mg658.00€500mg1,026.00€DIF-3
CAS:DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Formula:C13H17ClO4Purity:99.57%Color and Shape:SolidMolecular weight:272.72Ref: TM-T60485
1mg96.00€5mg222.00€10mg333.00€25mg557.00€50mg795.00€100mg1,071.00€500mg2,187.00€1mL*10mM (DMSO)205.00€116-9e
CAS:116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.Formula:C31H32N2O5Purity:99.55%Color and Shape:SolidMolecular weight:512.6Ref: TM-T25770
1mg50.00€5mg105.00€10mg170.00€25mg355.00€50mg595.00€100mg862.00€200mg1,153.00€1mL*10mM (DMSO)34.00€hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formula:C21H23FN4OPurity:99.87%Color and Shape:SolidMolecular weight:366.43Ref: TM-T11031
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)266.00€hSMG-1 inhibitor 11e
CAS:hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.Formula:C26H27N7O3SPurity:99.89%Color and Shape:SolidMolecular weight:517.6SJ572403
CAS:SJ572403 inhibits p27 protein, Kd 2.2 mM at D2 subdomain of p27-KID; useful in disordered protein disease research.Formula:C13H17N5O2Purity:99.93%Color and Shape:SolidMolecular weight:275.31Ref: TM-T16889
1mg39.00€5mg86.00€10mg119.00€25mg231.00€50mg371.00€100mg537.00€200mg710.00€1mL*10mM (DMSO)95.00€NSC16168
CAS:NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.Formula:C17H15NO9S3Purity:99.88%Color and Shape:SolidMolecular weight:473.5Ref: TM-T16351
1mg60.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)135.00€(S)-PF-06873600
CAS:(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.Formula:C20H27F2N5O4SPurity:98.59%Color and Shape:SolidMolecular weight:471.52Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formula:C6H11N3O4Purity:99.8%Color and Shape:SolidMolecular weight:189.17YK-2-69
CAS:YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Formula:C25H27FN8OSPurity:98.61% - 99.64%Color and Shape:SolidMolecular weight:506.6PCSK9-IN-10
CAS:PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.Formula:C18H23N5O4Purity:99.06%Color and Shape:SoildMolecular weight:373.41Ref: TM-T72025
2mg39.00€5mg60.00€10mg96.00€25mg170.00€50mg266.00€100mg391.00€200mg555.00€1mL*10mM (DMSO)62.00€Kif15-IN-2
CAS:Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.Formula:C20H20N6O4SPurity:98.17%Color and Shape:SolidMolecular weight:440.48CDK9-IN-19
CAS:CDK9-IN-19: Potent CDK9 inhibitor, anti-cancer, moderate pharmacokinetics, low hERG impact, effective in AML research.Formula:C26H22F2N4O5Color and Shape:SolidMolecular weight:508.47BIO-7662
CAS:BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.Formula:C38H48N6O8SPurity:98%Color and Shape:SolidMolecular weight:748.898-Azahypoxanthine
CAS:8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.Formula:C4H3N5OPurity:99.66%Color and Shape:Light Yellow To Light Beige Fine CrystallineMolecular weight:137.1FT206
CAS:FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].Formula:C25H29N5OSColor and Shape:SolidMolecular weight:447.6TC-I 15
CAS:α2β1 integrin inhibitorFormula:C23H28N4O6S2Purity:98%Color and Shape:SolidMolecular weight:520.62BVDU 5′-Triphosphate
CAS:BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.Formula:C11H16BrN2O14P3Purity:98%Color and Shape:SolidMolecular weight:573.08Riviciclib
CAS:Riviciclib, a CDK inhibitor (CDK9/T1, CDK4/D1, CDK1/B), has IC50s: 20, 63, 79 nM respectively, and fights cisplatin-resistant tumors.Formula:C21H20ClNO5Purity:98%Color and Shape:SolidMolecular weight:401.84CCT251455
CAS:CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.
Formula:C26H26ClN7O2Purity:99.1% - 99.1%Color and Shape:SolidMolecular weight:503.98m-Se3
CAS:m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].Formula:C29H23IN2SePurity:98%Color and Shape:SolidMolecular weight:605.37Trovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formula:C21H19F3N4O6SPurity:99.18%Color and Shape:SolidMolecular weight:512.46Litronesib
CAS:Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Formula:C23H37N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.7GSK2163632A
CAS:GSK2163632A is an insulin-like growth factor 1 receptor inhibitor that acts by binding to a novel region of the GRK active site cleft.Formula:C27H32N8O3SColor and Shape:SolidMolecular weight:548.66ML 315 hydrochloride
CAS:ML 315, a selective dual inhibitor targeting CDK (Cyclin-Dependent Kinase) and DYRK (Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase) with IC50 values of 68 nM and 282 nM, respectively, is utilized in research pertaining to cancer and neurological diseases [1].
Formula:C18H14Cl3N3O2Color and Shape:SolidMolecular weight:410.6825,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS:5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.Formula:C21H26N6O6Color and Shape:SolidMolecular weight:458.47KM05382
CAS:KM05382 inhibits CDK9 and the transcription of GAPDH.Formula:C20H19ClN2O3S2Color and Shape:SolidMolecular weight:434.96Methotrexate-γ-aspartate
CAS:Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.Formula:C24H27N9O8Purity:98%Color and Shape:SolidMolecular weight:569.53Antifolate C1
CAS:Antifolate C1 blocks purine creation, favors uptake via folate receptors/PCFT over RFC.Formula:C19H21N5O6SColor and Shape:SolidMolecular weight:447.465-DACTHF
CAS:5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.Formula:C19H24N6O6Purity:98%Color and Shape:SolidMolecular weight:432.43Diazoketone methotrexate
CAS:Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.Formula:C21H22N10O4Color and Shape:SolidMolecular weight:478.46αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49IIIM-290
CAS:IIIM-290 is an oral CDK inhibitor (IC50s: 90 and 94 nM for CDK2/A and CDK9/T1).Formula:C23H21Cl2NO5Purity:98%Color and Shape:SolidMolecular weight:462.32TAS-114
CAS:TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.Formula:C21H29N3O6SPurity:99.76%Color and Shape:SolidMolecular weight:451.54CCT241533
CAS:CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Formula:C23H27FN4O4Purity:98%Color and Shape:SolidMolecular weight:442.48PVZB1194
CAS:PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFormula:C13H9F4NO2SPurity:98%Color and Shape:SolidMolecular weight:319.28Spirofylline
CAS:Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.Formula:C24H28N6O5Purity:98%Color and Shape:SolidMolecular weight:480.52ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurity:99.67%Color and Shape:SolidMolecular weight:363.23Ref: TM-T13147
1mg175.00€5mg371.00€10mg557.00€25mg887.00€50mg1,198.00€100mg1,611.00€500mg3,232.00€1mL*10mM (DMSO)409.00€TNP-351
CAS:Tnp 351 is a novel antifolate drug being assessed for chemotherapy of lung cancer.Formula:C21H24N6O5Color and Shape:SolidMolecular weight:440.45Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27Phototrexate
CAS:Phototrexate, a photochromic Methotrexate analog, is a UVA-activated, reversible DHFR inhibitor with antifolate properties (IC50: 6 nM cis vs. 34 μM trans).Formula:C20H19N7O5Color and Shape:SolidMolecular weight:437.41Lamifiban
CAS:Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.Formula:C24H28N4O6Purity:98%Color and Shape:SolidMolecular weight:468.5DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg90.00€5mg253.00€10mg379.00€25mg640.00€50mg892.00€100mg1,224.00€1mL*10mM (DMSO)275.00€Sovesudil
CAS:Sovesudil (PHP-201) is a potent ROCK inhibitor with IC50 of 3.7 nM/2.3 nM for ROCK-I/II; lowers IOP without hyperemia.Formula:C23H22FN3O3Color and Shape:SolidMolecular weight:407.445'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
CAS:5'-ODMT cEt N-Bzm5 C Phosphoramidite is a strong modified nucleic acid analog for antisense oligos.Formula:C49H56N5O9PColor and Shape:SolidMolecular weight:889.97PD-L1-IN-2
CAS:PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.Formula:C33H38N4O6Purity:98%Color and Shape:SolidMolecular weight:586.68ROCK-IN-9
CAS:ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.Formula:C20H20FN5O2Purity:98%Color and Shape:SolidMolecular weight:381.4NTRC 0066-0
CAS:NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.Formula:C33H39N7O2Purity:98.30%Color and Shape:SolidMolecular weight:565.71SC-52012
CAS:SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.Formula:C25H30N4O6Purity:97.20%Color and Shape:SolidMolecular weight:482.53WRN inhibitor 1
CAS:WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.Formula:C16H13FN2O4SPurity:98%Color and Shape:SolidMolecular weight:348.35UNC-2170
CAS:UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.Formula:C14H21BrN2OPurity:97.44%Color and Shape:SolidMolecular weight:313.23Ref: TM-T24925
5mg46.00€10mg71.00€25mg138.00€50mg200.00€100mg284.00€200mg391.00€1mL*10mM (DMSO)57.00€TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Formula:C19H29ClN6OPurity:98%Color and Shape:SolidMolecular weight:392.93COH1
CAS:COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].Formula:C11H10N2O3SPurity:98%Color and Shape:SolidMolecular weight:250.27Fosfluridine tidoxil
CAS:Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.Formula:C34H62FN2O10PSColor and Shape:SolidMolecular weight:740.9L-739758
CAS:L-739758 is a glycoprotein IIb/IIIa inhibitor.Formula:C22H26N4O5S3Color and Shape:SolidMolecular weight:522.66DCB-3503
CAS:DCB-3503, a tylophorine analog, may fight cancer and aid immunosuppression by hindering protein synthesis and modulating HSC70 ATPase function.Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47T521
CAS:T521 is a selective inhibitor of the PBD of Plk1 and shows no inhibitory effect on Plk2 and Plk3.Formula:C17H14FNO5S2Purity:99.71%Color and Shape:SolidMolecular weight:395.43
