Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3480 products of "Cell Cycle/Checkpoint"
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Obtustatin
<p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>Formula:C184H284N52O57S8Purity:98%Color and Shape:SolidMolecular weight:4393.07Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formula:C42H50N7O7PColor and Shape:SolidMolecular weight:795.878(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Formula:C23H30N6O3S2Purity:99.42%Color and Shape:SoildMolecular weight:502.65WAY-647802
CAS:<p>WAY-647802 is a CDK inhibitor.</p>Formula:C11H14N4O3Purity:99.53%Color and Shape:SolidMolecular weight:250.25JB300
CAS:<p>JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.</p>Formula:C43H45ClFN7O10SColor and Shape:SolidMolecular weight:906.375Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formula:C12H12O9Color and Shape:SolidMolecular weight:300.22Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.455'-O-DMT-ibu-dC
CAS:<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Formula:C34H37N3O7Color and Shape:SolidMolecular weight:599.67Pseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Formula:C27H23ClF2N4O2Color and Shape:SolidMolecular weight:508.947ONX 0801 trisodium
CAS:<p>ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.</p>Formula:C32H30N5Na3O10Color and Shape:SolidMolecular weight:713.58CD532 hydrochloride
<p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>Color and Shape:Solid5'-O-DMT-N4-Bz-2'-F-dC
CAS:<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Formula:C37H34FN3O7Color and Shape:SolidMolecular weight:651.685'(R)-C-Methyl-5-fluorouridine
<p>5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.</p>Formula:C10H13FN2O6Color and Shape:SolidMolecular weight:276.22Nusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Purity:98.62%Color and Shape:SolidHeliquinomycin
CAS:<p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>Formula:C33H30O17Color and Shape:SolidMolecular weight:698.586Etrolizumab
CAS:<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Purity:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidCytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Formula:C9H16N3O14P3Color and Shape:SolidMolecular weight:483.162'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formula:C10H14N5Na2O8PColor and Shape:SolidMolecular weight:409.202wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Color and Shape:Odour Solid(1S,3R,5R)-PIM447 dihydrochloride
<p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>Formula:C24H25Cl2F3N4OPurity:98%Color and Shape:SolidMolecular weight:513.38
