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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • SNX7
    Targetmol
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    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Formula:C15H14N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:238.28

    Ref: TM-T77613

  • WAY-647802
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    WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:250.25

    Ref: TM-T9971

  • CymitQuimica logo
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    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T78307

  • Remdesivir nucleoside monophosphate
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    Remdesivir nucleoside monophosphate

    CAS:
    <p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>
    Formula:C12H14N5O7P
    Color and Shape:Solid
    Molecular weight:371.24

    Ref: TM-T39334

  • (+)-Glaucarubinone
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    (+)-Glaucarubinone

    <p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>
    Formula:C25H34O10
    Color and Shape:Solid
    Molecular weight:494.537

    Ref: TM-T126136

  • Ac-MRGDH-NH2
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    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727

    Ref: TM-TP3057

  • Pseudorabies virus-IN-1
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    Pseudorabies virus-IN-1

    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947

    Ref: TM-T206101

  • GRGDSP
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    GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Formula:C22H37N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.58

    Ref: TM-TP1421

  • Gly-Arg-Gly-Asp-Ser
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    Gly-Arg-Gly-Asp-Ser

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>
    Formula:C17H30N8O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.47

    Ref: TM-TP1459

  • CymitQuimica logo
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    Antibacterial agent 271

    <p>Antibacterialagent 271 is an antimicrobial compound that significantly inhibits Escherichia coli, with a minimum inhibitory concentration (MIC) of 2.2 μM. It disrupts bacterial membrane integrity, reducing metabolic activity. By binding to DNA grooves, it inhibits replication and induces reactive oxygen species (ROS) accumulation, leading to bacterial death. Antibacterialagent 271 shows considerable potential in combating bacterial infections.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206586

  • TAS-119
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    TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36

    Ref: TM-T34787

  • CymitQuimica logo
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    Farletuzumab

    CAS:
    <p>Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.36 kDa

    Ref: TM-T76720

  • CTP Synthetase-IN-1 Ammonium salt
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    CTP Synthetase-IN-1 Ammonium salt

    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:529.56

    Ref: TM-T72505L

  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
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    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    <p>6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and</p>
    Formula:C11H15N5O4
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T75185

  • (1S,3R,5R)-PIM447 dihydrochloride
    Targetmol
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    (1S,3R,5R)-PIM447 dihydrochloride

    <p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>
    Formula:C24H25Cl2F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:513.38

    Ref: TM-T13425

  • CymitQuimica logo
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    CD532 hydrochloride

    <p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>
    Color and Shape:Solid

    Ref: TM-T36932

  • Clofarabine-5'-diphosphate
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    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64

    Ref: TM-T203181

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    N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Formula:C41H43N3O9
    Color and Shape:Solid
    Molecular weight:721.79

    Ref: TM-T75224

  • Isocytosine
    Targetmol
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    Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C4H5N3O
    Color and Shape:White To Off-White Solid
    Molecular weight:111.1

    Ref: TM-PDK0016

  • CCT241533 dihydrochloride
    Targetmol
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    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41

    Ref: TM-T36704