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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3675 products of "Cell Cycle/Checkpoint"

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  • CDK-IN-2

    CAS:
    <p>CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: &lt;8 nM).</p>
    Formula:C18H19ClFN3O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:363.81
  • NR2F6 modulator-1

    CAS:
    NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.
    Formula:C23H17NO5S
    Purity:98.31%
    Color and Shape:Solid
    Molecular weight:419.45
  • UMK57

    CAS:
    UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,
    Formula:C17H17N3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:295.4
  • ERCC1-XPF-IN-2

    CAS:
    <p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>
    Formula:C15H13Cl2NO3
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:326.17
  • AGX51

    CAS:
    <p>AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.</p>
    Formula:C27H29NO4
    Purity:97.65%
    Color and Shape:Oil
    Molecular weight:431.52
  • hSMG-1 inhibitor 11e

    CAS:
    <p>hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 &lt;0.05 nM) and can be used in studies about cancer treatment.</p>
    Formula:C26H27N7O3S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:517.6
  • CDK4/6/1 Inhibitor

    CAS:
    <p>CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).</p>
    Formula:C28H30F2N6
    Purity:99.26% - 99.72%
    Color and Shape:Solid
    Molecular weight:488.57
  • CHD1Li 6.11

    CAS:
    <p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>
    Formula:C21H22BrN5OS
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:472.4
  • dCeMM2

    CAS:
    dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.
    Formula:C16H11ClN6OS
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:370.82
  • NSC16168

    CAS:
    NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.
    Formula:C17H15NO9S3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:473.5
  • Peldesine

    CAS:
    Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.
    Formula:C12H11N5O
    Purity:99.27% - 99.9%
    Color and Shape:Solid
    Molecular weight:241.25
  • Anticancer agent 73

    CAS:
    Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.
    Formula:C14H15NO4
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:261.27
  • 6RK73

    CAS:
    <p>6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).</p>
    Formula:C13H17N5O2S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:307.37
  • CRT-0105950

    CAS:
    <p>CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>
    Formula:C21H16ClN3OS
    Purity:99.78% - 99.86%
    Color and Shape:Solid
    Molecular weight:393.89
  • Talviraline

    CAS:
    <p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>
    Formula:C15H20N2O3S2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:340.46
  • DS18561882

    CAS:
    DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.
    Formula:C28H31F3N4O6S
    Purity:98.19% - >99.99%
    Color and Shape:Solid
    Molecular weight:608.63
  • CDK9-IN-10

    CAS:
    CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.
    Formula:C22H16O5
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:360.36
  • BML-259

    CAS:
    <p>BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.</p>
    Formula:C14H16N2OS
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:260.35
  • Cytembena

    CAS:
    <p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>
    Formula:C11H8BrNaO4
    Purity:99.35%
    Color and Shape:White Powder
    Molecular weight:307.07
  • RP-6306

    CAS:
    <p>Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.</p>
    Formula:C18H20N4O2
    Purity:98.41% - 99.28%
    Color and Shape:Solid
    Molecular weight:324.38