Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(100 products)
- CDK(520 products)
- Cell Cycle Arrest(4 products)
- Chk(43 products)
- DYRK(48 products)
- Dynamin(25 products)
- Ferroptosis(218 products)
- HSP(173 products)
- Integrin(248 products)
- Kinesin(75 products)
- LIM Kinase(19 products)
- Microtubule Associated(279 products)
- PKC(107 products)
- PLK(26 products)
- ROCK(68 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(73 products)
Show 10 more subcategories
Found 3655 products of "Cell Cycle/Checkpoint"
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Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formula:C27H27F2NO6Purity:99.16%Color and Shape:SolidMolecular weight:499.5Abemaciclib metabolite M20
CAS:<p>Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。</p>Formula:C27H32F2N8OPurity:98.1% - 99.08%Color and Shape:SolidMolecular weight:522.59Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formula:C22H32N4O4Purity:98.76%Color and Shape:SolidMolecular weight:416.51SB 328437
CAS:<p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>Formula:C21H18N2O5Purity:99.54%Color and Shape:SolidMolecular weight:378.38dCeMM2
CAS:dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Formula:C16H11ClN6OSPurity:99.68%Color and Shape:SolidMolecular weight:370.82ERCC1-XPF-IN-2
CAS:<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formula:C15H13Cl2NO3Purity:98.21%Color and Shape:SolidMolecular weight:326.17CDK-IN-2
CAS:<p>CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).</p>Formula:C18H19ClFN3O2Purity:99.67%Color and Shape:SolidMolecular weight:363.81COH34
CAS:COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.Formula:C18H15NOSPurity:99.57%Color and Shape:SolidMolecular weight:293.38hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formula:C21H23FN4OPurity:99.87%Color and Shape:SolidMolecular weight:366.43hSMG-1 inhibitor 11e
CAS:<p>hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.</p>Formula:C26H27N7O3SPurity:99.89%Color and Shape:SolidMolecular weight:517.6RP-6685
CAS:RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Formula:C22H14F7N5OPurity:99.65%Color and Shape:SoildMolecular weight:497.37PS423
CAS:<p>PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.</p>Formula:C25H23F3O9Purity:98.81% - 99.26%Color and Shape:SolidMolecular weight:524.44Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formula:C14H11BrN4O3SPurity:97.27%Color and Shape:SolidMolecular weight:395.23Netivudine
CAS:<p>Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.</p>Formula:C12H14N2O6Purity:99.78%Color and Shape:SolidMolecular weight:282.25PCSK9-IN-10
CAS:<p>PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.</p>Formula:C18H23N5O4Purity:99.06%Color and Shape:SoildMolecular weight:373.41BioE-1115
CAS:<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Formula:C19H18FN3O2Purity:97.54%Color and Shape:SolidMolecular weight:339.36GS-6620 PM
CAS:<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Formula:C13H15N5O4Purity:98.52% - 98.7%Color and Shape:SolidMolecular weight:305.29TC-S 7005
CAS:TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Formula:C21H17N3O3Purity:99.516%Color and Shape:SolidMolecular weight:359.38AGX51
CAS:<p>AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.</p>Formula:C27H29NO4Purity:97.65%Color and Shape:OilMolecular weight:431.52CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formula:C11H8F3N3OPurity:98.48%Color and Shape:SolidMolecular weight:255.2
