CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3655 products of "Cell Cycle/Checkpoint"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • NSC16168
    Targetmol
    + Info

    NSC16168

    CAS:
    NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.
    Formula:C17H15NO9S3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:473.5

    Ref: TM-T16351

  • PF-6808472
    Targetmol
    + Info

    PF-6808472

    CAS:
    PF-6808472 is a cell-permeable covalent kinase probe, reacts with conserved lysine residues within the ATP-binding site of kinases.
    Formula:C25H27FN8O3S
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:538.6

    Ref: TM-T33955

  • N-desmethyl Netupitant
    Targetmol
    + Info

    N-desmethyl Netupitant

    CAS:
    <p>N-desmethyl Netupitant is a metabolite of Netupitant and a potential Substance-P receptor agonist.</p>
    Formula:C29H30F6N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.57

    Ref: TM-T12212

  • CDK9-IN-9
    Targetmol
    + Info

    CDK9-IN-9

    CAS:
    <p>CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).</p>
    Formula:C22H23F2N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.51

    Ref: TM-T10747

  • 2'-Deoxypseudoisocytidine
    Targetmol
    + Info

    2'-Deoxypseudoisocytidine

    CAS:
    2'-Deoxypseudoisocytidine is a nucleoside analogue.
    Formula:C9H13N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:227.22

    Ref: TM-T10099

  • 5-Iodo-indirubin-3'-monoxime
    Targetmol
    + Info

    5-Iodo-indirubin-3'-monoxime

    CAS:
    5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s
    Formula:C16H10IN3O2
    Color and Shape:Solid
    Molecular weight:403.17

    Ref: TM-T10172

  • USP1-IN-5
    Targetmol
    + Info

    USP1-IN-5

    CAS:
    <p>USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than</p>
    Formula:C27H23F3N8O
    Color and Shape:Solid
    Molecular weight:532.52

    Ref: TM-T79795

  • CDK7-IN-22
    Targetmol
    + Info

    CDK7-IN-22

    CAS:
    CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].
    Formula:C22H25F3N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.47

    Ref: TM-T79169

  • PD-1/PD-L1-IN-33
    Targetmol
    + Info

    PD-1/PD-L1-IN-33

    CAS:
    PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor, effectively impedes the interaction between PD-1 and PD-L1 with an IC50 of 6.3 nM.
    Formula:C26H27N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:425.53

    Ref: TM-T79643

  • DNA gyrase B-IN-3
    Targetmol
    + Info

    DNA gyrase B-IN-3

    CAS:
    DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram
    Formula:C14H9Cl2N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.21

    Ref: TM-T78776

  • RNA polymerase II-IN-1
    Targetmol
    + Info

    RNA polymerase II-IN-1

    CAS:
    <p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>
    Formula:C38H53N11O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:887.96

    Ref: TM-T74630

  • PD-1/PD-L1-IN-34
    Targetmol
    + Info

    PD-1/PD-L1-IN-34

    CAS:
    PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) effectively inhibits the PD-1/PD-L1 interaction (IC 50 = 0.029 μM) and demonstrates selective binding affinity to PD-L1
    Formula:C35H33ClN2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.1

    Ref: TM-T79205

  • Aurora Kinases-IN-4
    Targetmol
    + Info

    Aurora Kinases-IN-4

    CAS:
    <p>Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.</p>
    Formula:C26H28N8O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.55

    Ref: TM-T78753

  • DNA polymerase-IN-3
    Targetmol
    + Info

    DNA polymerase-IN-3

    CAS:
    DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in
    Formula:C13H12O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:232.23

    Ref: TM-T79308

  • PD-1/PD-L1-IN-26
    Targetmol
    + Info

    PD-1/PD-L1-IN-26

    CAS:
    PD-1/PD-L1-IN-26 is a strong inhibitor with IC50 of 0.0380 μM that may boost immune response in cancer by aiding CD4+ T cell entry to tumors.
    Formula:C43H52N4O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:752.89

    Ref: TM-T72668

  • PD-1/PD-L1-IN-27
    Targetmol
    + Info

    PD-1/PD-L1-IN-27

    CAS:
    PD-1/PD-L1-IN-27: potent anti-cancer, IC50 134nM, minimal T cell harm, boosts CD8+ T cells, reduces fatigue.
    Formula:C44H35NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.75

    Ref: TM-T72680

  • Tirofiban HCl
    Targetmol
    + Info

    Tirofiban HCl

    CAS:
    <p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>
    Formula:C22H37ClN2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.06

    Ref: TM-T20552

  • 8-NH2-ATP tetrasodium
    Targetmol
    + Info

    8-NH2-ATP tetrasodium

    CAS:
    <p>8-NH2-ATP tetrasodium, an inactive ATP variant, originates from 8-NH2-Ado tetrasodium, which triggers the apoptosis-associated cleavage of poly (ADP-ribose) polymerase [1] [2].</p>
    Formula:C10H13N6Na4O13P3
    Color and Shape:Solid
    Molecular weight:610.12

    Ref: TM-T84731

  • KY386
    Targetmol
    + Info

    KY386

    CAS:
    <p>KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM.</p>
    Formula:C21H19N5O2S
    Color and Shape:Solid
    Molecular weight:405.47

    Ref: TM-T81967

  • Cdc7-IN-7
    Targetmol
    + Info

    Cdc7-IN-7

    CAS:
    <p>Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.</p>
    Formula:C21H22N4O5
    Purity:98.78%
    Color and Shape:Solid
    Molecular weight:410.42

    Ref: TM-T10729