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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3495 products of "Cell Cycle/Checkpoint"

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  • UNC-2170

    CAS:
    <p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>
    Formula:C14H21BrN2O
    Purity:97.44%
    Color and Shape:Solid
    Molecular weight:313.23
  • Inixaciclib

    CAS:
    <p>Inixaciclib is a potent CDK inhibitor, can be used to research anticancer.</p>
    Formula:C26H30F2N6O
    Color and Shape:Solid
    Molecular weight:480.55
  • L 738167

    CAS:
    <p>L 738167 is a potent antagonist of the long-acting fibrinogen receptor.</p>
    Formula:C25H34N6O6S
    Color and Shape:Solid
    Molecular weight:546.64
  • Pencitabine

    CAS:
    <p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>
    Formula:C15H20F3N3O6
    Color and Shape:Solid
    Molecular weight:395.33
  • SC-52012

    CAS:
    <p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>
    Formula:C25H30N4O6
    Purity:97.20%
    Color and Shape:Solid
    Molecular weight:482.53
  • CDK9-IN-8

    CAS:
    <p>CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).</p>
    Formula:C31H32FN7O3
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:569.63
  • Balapiravir hydrochloride

    CAS:
    <p>Balapiravir HCl, an NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>
    Formula:C21H31ClN6O8
    Color and Shape:Solid
    Molecular weight:530.96
  • c-Myc inhibitor 8

    CAS:
    <p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>
    Formula:C19H12BrClF3NO3S2
    Color and Shape:Solid
    Molecular weight:538.79
  • CCT241533 hydrochloride

    CAS:
    CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
    Formula:C23H28ClFN4O4
    Purity:97.13%
    Color and Shape:Solid
    Molecular weight:478.95
  • FT206

    CAS:
    <p>FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].</p>
    Formula:C25H29N5OS
    Color and Shape:Solid
    Molecular weight:447.6
  • NTRC 0066-0

    CAS:
    <p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>
    Formula:C33H39N7O2
    Purity:98.30%
    Color and Shape:Solid
    Molecular weight:565.71
  • 2'-Deoxypseudoisocytidine

    CAS:
    <p>2'-Deoxypseudoisocytidine is a nucleoside analogue.</p>
    Formula:C9H13N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:227.22
  • Lotrafiban

    CAS:
    <p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>
    Formula:C23H32N4O4
    Color and Shape:Solid
    Molecular weight:428.52
  • CI 972 anhydrous

    CAS:
    <p>CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.</p>
    Formula:C11H12ClN5OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.76
  • ROCK-IN-10

    CAS:
    <p>ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].</p>
    Formula:C25H25N5O3
    Color and Shape:Solid
    Molecular weight:443.507
  • BI-1950

    CAS:
    <p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>
    Formula:C32H26Cl2FN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:646.5
  • DAM-IN-1

    CAS:
    <p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>
    Formula:C16H17NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.31
  • Solitomab

    CAS:
    <p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>
    Color and Shape:Liquid
  • SZ-015268

    CAS:
    <p>SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.</p>
    Formula:C25H38N8O3
    Color and Shape:Solid
    Molecular weight:498.62
  • LX7101 hydrochloride

    CAS:
    <p>LX7101 is a potent inhibitor of both LIM kinase (LIMK) 1 and 2, and Rho-associated kinase 1 (ROCK1) and ROCK2, with IC50 values of 32, 4.3, 69, and 32 nM, respectively. It is selective, demonstrated by its lack of cross-reactivity in a panel of binding assays involving 78 receptors, transporters, and an additional 430 kinases, at a concentration of 10 μM. The topical administration of LX7101 (3 μl of a 1 mg/ml solution) to the eye has been shown to reduce intraocular pressure in a dexamethasone-induced mouse model of glaucoma.</p>
    Formula:C23H29N7O3HCl
    Color and Shape:Solid
    Molecular weight:488