
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(95 products)
- CDK(502 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(226 products)
- Kinesin(68 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(68 products)
Show 10 more subcategories
Found 3493 products of "Cell Cycle/Checkpoint"
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RNA polymerase II-IN-1
CAS:<p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>Formula:C38H53N11O12SPurity:98%Color and Shape:SolidMolecular weight:887.96Bisindolylmaleimide X hydrochloride
CAS:<p>Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).</p>Formula:C26H25ClN4O2Purity:99.23%Color and Shape:SolidMolecular weight:460.96Antifolate C1
CAS:<p>Antifolate C1 blocks purine creation, favors uptake via folate receptors/PCFT over RFC.</p>Formula:C19H21N5O6SColor and Shape:SolidMolecular weight:447.46α7β1 integrin modulator-1
CAS:<p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56AR-13503
CAS:<p>AR-13503, a Netarsudil metabolite, is a ROCK inhibitor, potentially treating glaucoma and lowering eye pressure.</p>Formula:C19H19N3O2Color and Shape:SolidMolecular weight:321.37OXA-06 hydrochloride
CAS:<p>OXA-06 hydrochloride, an ATP-competitive ROCK inhibitor, impedes anchorage-dependent growth and invasion in non-small cell lung cancer cell lines. It effectively inhibits cofilin phosphorylation without inducing apoptosis [1].</p>Formula:C21H20Cl2FN3Color and Shape:SolidMolecular weight:404.31Votoplam
CAS:<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Formula:C21H25N9OPurity:98%Color and Shape:SolidMolecular weight:419.48Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Formula:C28H31ClN6O3Color and Shape:SolidMolecular weight:535.04CDK9-IN-9
CAS:<p>CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).</p>Formula:C22H23F2N5O2SPurity:98%Color and Shape:SolidMolecular weight:459.51SB-743921 free base
CAS:<p>SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).</p>Formula:C31H33ClN2O3Purity:98%Color and Shape:SolidMolecular weight:517.06BVDU 5′-Triphosphate
CAS:<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Formula:C11H16BrN2O14P3Purity:98%Color and Shape:SolidMolecular weight:573.08ASC-69
CAS:<p>ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].</p>Formula:C19H19N7Purity:98%Color and Shape:SolidMolecular weight:345.4m-Se3
CAS:<p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>Formula:C29H23IN2SePurity:98%Color and Shape:SolidMolecular weight:605.37JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formula:C29H38N4O3Purity:98%Color and Shape:SolidMolecular weight:490.64PLK1-IN-4
CAS:<p>PLK1-IN-4: strong PLK1 blocker (<0.508 nM IC50), inhibits cancer cell growth, triggers G2/M arrest and apoptosis.</p>Formula:C24H25F3N6O4SColor and Shape:SolidMolecular weight:550.555-DACTHF
CAS:<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Formula:C19H24N6O6Purity:98%Color and Shape:SolidMolecular weight:432.43αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49PVZB1194
CAS:<p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>Formula:C13H9F4NO2SPurity:98%Color and Shape:SolidMolecular weight:319.28DUB-IN-7
CAS:<p>DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].</p>Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37Synstatin (92-119)
CAS:<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Formula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27
