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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3493 products of "Cell Cycle/Checkpoint"

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  • Diazoketone methotrexate
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    Diazoketone methotrexate

    CAS:
    <p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>
    Formula:C21H22N10O4
    Color and Shape:Solid
    Molecular weight:478.46

    Ref: TM-T25322

  • PD-L1-IN-2
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    PD-L1-IN-2

    CAS:
    <p>PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.</p>
    Formula:C33H38N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.68

    Ref: TM-T78053

  • PF-6808472
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    PF-6808472

    CAS:
    <p>PF-6808472 is a cell-permeable covalent kinase probe, reacts with conserved lysine residues within the ATP-binding site of kinases.</p>
    Formula:C25H27FN8O3S
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:538.6

    Ref: TM-T33955

  • 8-Azahypoxanthine
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    8-Azahypoxanthine

    CAS:
    <p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>
    Formula:C4H3N5O
    Purity:99.66%
    Color and Shape:Light Yellow To Light Beige Fine Crystalline
    Molecular weight:137.1

    Ref: TM-T20102

  • Methotrexate-γ-aspartate
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    Methotrexate-γ-aspartate

    CAS:
    <p>Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.</p>
    Formula:C24H27N9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:569.53

    Ref: TM-T24457

  • T521
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    T521

    CAS:
    <p>T521 is a selective inhibitor of the PBD of Plk1 and shows no inhibitory effect on Plk2 and Plk3.</p>
    Formula:C17H14FNO5S2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:395.43

    Ref: TM-T28904

  • N-desmethyl Netupitant
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    N-desmethyl Netupitant

    CAS:
    <p>N-desmethyl Netupitant is a metabolite of Netupitant and a potential Substance-P receptor agonist.</p>
    Formula:C29H30F6N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.57

    Ref: TM-T12212

  • Xylocydine
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    Xylocydine

    CAS:
    <p>Xylocydine is a novel Cdk inhibitor that induces apoptosis in HCC, suppresses tumor growth, and is non-toxic to other tissues.</p>
    Formula:C12H14BrN5O5
    Color and Shape:Solid
    Molecular weight:388.17

    Ref: TM-T68875

  • 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
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    5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

    CAS:
    <p>5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].</p>
    Formula:C49H54N7O8P
    Color and Shape:Solid
    Molecular weight:899.97

    Ref: TM-T74702

  • FT206
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    FT206

    CAS:
    <p>FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].</p>
    Formula:C25H29N5OS
    Color and Shape:Solid
    Molecular weight:447.6

    Ref: TM-T36306

  • WRN inhibitor 2
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    WRN inhibitor 2

    CAS:
    <p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>
    Formula:C15H11F3N2O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.38

    Ref: TM-T79178

  • NVS-SM2
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    NVS-SM2

    CAS:
    <p>NVS-SM2 boosts SMN2 splicing, enhances exon 7 inclusion, and raises SMN protein levels orally.</p>
    Formula:C23H30N6O
    Color and Shape:Solid
    Molecular weight:406.52

    Ref: TM-T33764

  • BIO-7662
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    BIO-7662

    CAS:
    BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.
    Formula:C38H48N6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.89

    Ref: TM-T23795

  • ML 315 hydrochloride
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    ML 315 hydrochloride

    CAS:
    <p>ML 315, a selective dual inhibitor targeting CDK (Cyclin-Dependent Kinase) and DYRK (Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase) with IC50 values of 68 nM and 282 nM, respectively, is utilized in research pertaining to cancer and neurological diseases [1].</p>
    Formula:C18H14Cl3N3O2
    Color and Shape:Solid
    Molecular weight:410.682

    Ref: TM-T84712

  • USP7-IN-13
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    USP7-IN-13

    CAS:
    <p>USP7-IN-13 (Compound 101), a USP7 inhibitor, exhibits an IC50 range of 0.2-1 μM and is applicable in researching multiple myeloma [1].</p>
    Formula:C24H28N4O3
    Color and Shape:Solid
    Molecular weight:420.5

    Ref: TM-T84710

  • Senexin C
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    Senexin C

    CAS:
    Senexin C is a CDK8/19 inhibitor with anticancer activity.Senexin C inhibits the growth of MV4-11 leukemia cells.
    Formula:C28H27N5O
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:449.55

    Ref: TM-T62702

  • Inixaciclib
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    Inixaciclib

    CAS:
    <p>Inixaciclib is a potent CDK inhibitor, can be used to research anticancer.</p>
    Formula:C26H30F2N6O
    Color and Shape:Solid
    Molecular weight:480.55

    Ref: TM-T69662

  • 3-Hydroxyxanthone
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    3-Hydroxyxanthone

    CAS:
    <p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>
    Formula:C13H8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:212.2

    Ref: TM-T78548

  • DNA Gyrase-IN-8
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    DNA Gyrase-IN-8

    CAS:
    <p>DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].</p>
    Formula:C19H14BrN5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.25

    Ref: TM-T78712

  • Leucettinib-92
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    Leucettinib-92

    CAS:
    <p>Leucettinib-92 (compound 92) is a kinase inhibitor selective for DYRK/CLK families, displaying IC50 values of 147 nM (CLK1), 39 nM (CLK2), 5.2 nM (CLK4), 0.8 μM</p>
    Formula:C21H22N4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.49

    Ref: TM-T79562