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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3904 products of "Cell Cycle/Checkpoint"

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  • Sarecycline hydrochloride

    CAS:
    Sarecycline hydrochloride is a narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity.
    Formula:C24H30ClN3O8
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:523.96

    Ref: TM-T21394

    1mg
    137.00€
    5mg
    385.00€
    10mg
    560.00€
    25mg
    872.00€
    50mg
    1,153.00€
    100mg
    1,584.00€
  • N1-Methylxylo-guanosine


    N1-Methylxylo-guanosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.
    Formula:C11H15N5O5
    Color and Shape:Solid
    Molecular weight:297.27

    Ref: TM-T75066

    5mg
    To inquire
    50mg
    To inquire
  • XY028-133

    CAS:

    XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.

    Formula:C53H67N11O7S
    Purity:97.11%
    Color and Shape:Solid
    Molecular weight:1002.23

    Ref: TM-T13361

    1mg
    116.00€
    5mg
    283.00€
    10mg
    494.00€
    25mg
    847.00€
    50mg
    1,491.00€
    100mg
    2,593.00€
  • αVβ8-IN-1

    CAS:
    αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).
    Formula:C25H32ClN5O4
    Color and Shape:Solid
    Molecular weight:502.01

    Ref: TM-T200044

    1mg
    305.00€
    5mg
    713.00€
    10mg
    1,161.00€
    25mg
    2,313.00€
    50mg
    3,115.00€
  • CDK2/PIM1-IN-1


    CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.
    Color and Shape:Odour Solid

    Ref: TM-T206369

    10mg
    To inquire
    50mg
    To inquire
  • FF-10502

    CAS:
    FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.
    Formula:C9H12FN3O3S
    Color and Shape:Solid
    Molecular weight:261.27

    Ref: TM-T39290

    25mg
    1,369.00€
  • RNA splicing modulator 1

    CAS:
    RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].
    Formula:C19H20N6OS
    Color and Shape:Solid
    Molecular weight:380.47

    Ref: TM-T74884

    5mg
    To inquire
    50mg
    To inquire
  • Heliquinomycin

    CAS:
    Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.
    Formula:C33H30O17
    Color and Shape:Solid
    Molecular weight:698.586

    Ref: TM-T36748

    1mg
    1,773.00€
  • R-1479

    CAS:
    R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.
    Formula:C9H12N6O5
    Purity:98.11% - 99.95%
    Color and Shape:Solid
    Molecular weight:284.23

    Ref: TM-TQ0162

    1mg
    104.00€
    5mg
    258.00€
    10mg
    358.00€
    25mg
    595.00€
    50mg
    842.00€
    100mg
    1,134.00€
    200mg
    1,521.00€
    1mL*10mM (DMSO)
    318.00€
  • 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine


    2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective
    Formula:C34H75FN9O12P3
    Color and Shape:Solid
    Molecular weight:913.93

    Ref: TM-T75207

    5mg
    To inquire
    50mg
    To inquire
  • BSJ-04-132


    Selective Cdk4 degrader. Degrades Cdk4 in Molt-4 cells, with no effect on Cdk6 levels. Displays cereblon-dependent degradation.
    Color and Shape:Liquid

    Ref: TM-T35476

    5mg
    260.00€
  • Chrysomycin A

    CAS:
    Chrysomycin A is an antibiotic that can be derived from Streptomyces.
    Formula:C28H28O9
    Color and Shape:Solid
    Molecular weight:508.52

    Ref: TM-T36467

    250µg
    310.00€
  • 2'-(2-Nitrobenzyl)-ATP trisodium


    2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.
    Formula:C17H18N6Na3O15P3
    Color and Shape:Solid
    Molecular weight:707.97361

    Ref: TM-T207170

    10mg
    To inquire
    50mg
    To inquire
  • Torvutatug

    CAS:
    Torvutatug is a human IgG1κ monoclonal antibody that acts against FOLR1.
    Color and Shape:Liquid

    Ref: TM-T9901A-894

    1mg
    To inquire
    5mg
    To inquire
  • N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine


    N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.
    Formula:C22H35N3O10
    Color and Shape:Solid
    Molecular weight:501.53

    Ref: TM-T75233

    5mg
    To inquire
    50mg
    To inquire
  • JB300

    CAS:
    JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.
    Formula:C43H45ClFN7O10S
    Color and Shape:Solid
    Molecular weight:906.375

    Ref: TM-T204223

    10mg
    To inquire
    50mg
    To inquire
  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and
    Formula:C11H15N5O4
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T75185

    25mg
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    50mg
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    100mg
    To inquire
  • 5'-O-TBDMS-dA

    CAS:

    5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.

    Formula:C16H27N5O3Si
    Color and Shape:Solid
    Molecular weight:365.509

    Ref: TM-T37143

    50mg
    49.00€
  • WAY-647802

    CAS:
    WAY-647802 is a CDK inhibitor.
    Formula:C11H14N4O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:250.25

    Ref: TM-T9971

    2mg
    39.00€
    5mg
    58.00€
    10mg
    86.00€
    25mg
    123.00€
    50mg
    183.00€
    100mg
    269.00€
    200mg
    383.00€
  • wrwyar-NH2 TFA


    wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.
    Color and Shape:Odour Solid

    Ref: TM-TP3210

    10mg
    To inquire
    50mg
    To inquire